3D-printing technologies and biomaterial innovations for bone tissue engineering: current status and future perspectives [0.03%]
用于骨组织工程的3D打印技术及生物材料创新：现状与未来展望
Shimaa Husien,Isra H Ali,Wael Mamdouh
Shimaa Husien
Bone fractures and osteoporosis-related defects continue to pose major global health and socioeconomic burdens, necessitating the development of advanced regenerative approaches. This review presents a comprehensive overview of bone anatomy...
Enhancement of wound healing through chitosan/gelatin/polyvinyl alcohol-based nanocomposites containing chrysin-loaded cerium oxide nanoparticles: a synergistic approach to tissue regeneration [0.03%]
载黄酮的二氧化铈纳米颗粒增强刺痛伤口愈合：基于壳聚糖/明胶/聚乙烯醇基纳米复合材料的组织再生协同策略
Marziyeh Shirvani-FilAbadi,Somayeh Reiisi,Sadegh Shirian
Marziyeh Shirvani-FilAbadi
Chronic and infected wounds remain a significant clinical challenge, requiring advanced therapeutic strategies to accelerate repair and improve outcomes. This study developed a chitosan/gelatin/polyvinyl alcohol (CS/GEL/PVA) nanocomposite i...
Formulation and evaluation of azithromycin loaded chitosan nanoparticles for its antibiofilm activity [0.03%]
用于其抗菌膜活性的阿奇霉素负载壳聚糖纳米颗粒的配方和评估
Chandana R,Ashvini H M
Chandana R
The present study focused on the formulation and evaluation of azithromycin-loaded chitosan nanoparticles (AZM-CSNPs) to enhance antimicrobial and antibiofilm efficacy. The nanoparticles were prepared by ionic gelation of chitosan with TPP,...
Evaluation of PLGA nanoparticle-based conjugate vaccines incorporating lipopolysaccharide and alginate for inducing immunity against P. aeruginosa: a rabbit model study [0.03%]
评估基于PLGA纳米颗粒的结合疫苗（结合脂多糖和海藻酸盐）诱发兔模型免疫系统对抗铜绿假单胞菌的免疫反应研究
Mohammad Hossein Mosannani,Masoud Maleki,Mojtaba Salouti et al.
Mohammad Hossein Mosannani et al.
A common Gram-negative bacterium, Pseudomonas aeruginosa poses a special risk to people with compromised immune systems, including those receiving chemotherapy, organ transplant recipients, and people with cystic fibrosis. The purpose of th...
Poly(lactic acid)/poly(arginine) nanoparticles loaded with resveratrol: antioxidant potential and biocompatibility [0.03%]
聚乳酸/聚精氨酸纳颗粒负载白藜芦醇：抗氧化活性及生物相容性
Daianne Leandro Padroni de Souza,Lívia Rodrigues de Menezes
Daianne Leandro Padroni de Souza
Resveratrol is a polyphenol with potent antioxidant activity; however, its application in topical formulations is limited by low aqueous solubility and poor stability. Polymeric nanoparticles represent an attractive strategy to overcome the...
Photo-crosslinked hyaluronic acid-based hydrogels for in vitro drug delivery [0.03%]
用于体外药物递送的光交联透明质酸基水凝胶
Jingke Zhang,Fengjiao Zhang,Sufeng Zhang et al.
Jingke Zhang et al.
Green and biocompatible formulation of arbutin encapsulated alginate nanoparticle: improved cytotoxicity against melanoma cancer and potent inhibition of melanin biosynthesis and L-DOPA auto-oxidation [0.03%]
一种绿色且生物相容性的熊果苷藻酸盐纳米颗粒制剂：改善的抗癌活性和抑制黑色素合成及L-多巴自动氧化作用
Mahmoud Omidi,Nikoo Ghasabeh Siahkal-Mahaleh,Seyyed Mobin Rahimnia et al.
Mahmoud Omidi et al.
The elevated melanin production within the skin results in a distressing pigmentation disorder called melanoma. This underscores the importance of developing effective therapeutic approaches, such as nano-delivery systems. The primary objec...
Advancements in chitosan-based hydrogel synthesis using ionizing radiation for medical purposes: opportunities and challenges [0.03%]
基于离子辐射的医用壳聚糖水凝胶合成研究进展：机遇与挑战
Muhammad Asim Raza,Sung Soo Han
Muhammad Asim Raza
Biocompatible hydrogels are crucial for biomedical applications, driving significant advancements in their fabrication through the use of ionizing radiation technology. This technology offers a promising eco-friendly alternative to conventi...
Bindi Ying,Meng Chen,Yanping Sun et al.
Bindi Ying et al.
Chronic wound infections in diabetes present significant clinical challenges due to their complex pathological microenvironment. Intelligent hydrogel dressings, with their three-dimensional network structure and high designability of functi...
Developing chitosan nanocomposite with silver nanoparticle, sesame oil, and Verbena officinalis extract for wound dressing: in vivo and in vitro evaluation [0.03%]
一种用于伤口敷料的壳聚糖纳米复合材料的开发：载有银纳米颗粒，芝麻油和Verbena Officinalis提取物的纳米复合材料的体内和体外评价
Negar Naghshineh,Kambiz Tahvildari,Akbar Esmaeili et al.
Negar Naghshineh et al.
This study develops two types of chitosan-based composite sponge containing silver nanoparticles and either verbena officinalis extract or sesame oil. An optimal solution of silver nanoparticles and chitosan was obtained from the antibacter...