An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics [0.03%]
微小核糖核酸与大流行性病毒性疾病：预测和防控大流行的下一个前沿领域
Niloofar Farsiu,Javad Charostad,Fatemeh Khodadadpour Mahani et al.
Niloofar Farsiu et al.
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression and play important roles in host-virus interactions. Increasing evidence indicates that viral infections can alter host miRNA expression profiles, influencing viral ...
Tissue-specific and sex-dependent microbiome structure in east African cattle ticks (Amblyomma gemma and Rhipicephalus pulchellus) and their bovine hosts [0.03%]
东非牛蜱（Amblyomma gemma 和Rhipicephalus pulchellus）及其反刍动物宿主的组织特异性和性别依赖性微生物群结构
Dennis Getange,Samson Mukaratirwa,Rua Khogali et al.
Dennis Getange et al.
Ticks and their vertebrate hosts share intimate ecological interactions that shape microbial community composition, with implications for tick fitness and pathogen transmission. However, the extent and specificity of tick-host microbial int...
Mapping of Streptococcus pneumoniae sequence types associated with multidrug resistance and capsular switching: A systematic review [0.03%]
用于多重耐药和荚膜转换的肺炎链球菌序列型分布图的系统评价
Samuel A Akwetey,Akosua B Karikari,Onyasaniba K Ntim et al.
Samuel A Akwetey et al.
Background: Streptococcus pneumoniae is a significant bacterial pathogen responsible for invasive and non-invasive infections. One of its most concerning traits is capsular switching, which can lead to multidrug resistanc...
Early-life acquisition of antimicrobial resistance genes and strain-level genomic concordance across maternal-infant compartments [0.03%]
母婴各部分之间的抗微生物药物耐药基因的早期获得及菌株水平的一致性分析
Jean Marc Mardirossian,Bahia Abdallah,Gavin M Douglas et al.
Jean Marc Mardirossian et al.
Background: Early-life microbial colonization and antimicrobial resistance gene (ARG) acquisition may influence long-term health outcomes. High-resolution genomic studies assessing strain-level concordance and resistome o...
Re-emergence of a highly pathogenic avian influenza H5N1 virus of clade 2.3.4.4b in poultry in France [0.03%]
法国家禽中高致病性禽流感H5N1(2.3.4.4b分支)病毒的再次出现
François-Xavier Briand,Claire Martenot,Pascale Massin et al.
François-Xavier Briand et al.
Two epidemic waves of the same HPAI H5N1 virus, three months apart, were observed in poultry farms in southwestern France in 2022-2023. The high genetic similarity of the viruses observed between the two waves suggests a re-emergence of the...
High frequency of the HLA-G*01:05N null allele in Beninese populations and its potential impact on reduced soluble HLA-G expression [0.03%]
贝宁人群中HLA-G*01：05N无功能等位基因的高频率及其对可溶性HLA-G表达降低的影响
Djelili Biaou,Marianne Lecat,Nayane S B Silva et al.
Djelili Biaou et al.
Human Leucocyte Antigen G (HLA), a non-classical HLA class Ib molecule, is involved in feto-maternal immune tolerance. Among HLA-G alleles, HLA-G*01:05N is defined by a cytosine deletion (ΔC) at exon 3, which causes a premature stop codon ...
Genomic and morphological analysis of human clinical Burkholderia pseudomallei isolates from New Caledonia (2021-2022) [0.03%]
2021至2022年新喀里多尼亚临床分离的鲍曼不动杆菌基因组和形态分析
Bernice Klotoe,Fabien Vorimore,Mégane Gasqué et al.
Bernice Klotoe et al.
Melioidosis is an infectious disease caused by the bacterium Burkholderia pseudomallei that is prevalent in New Caledonia. This study aimed to characterize recent human cases, evaluate the genomic diversity of circulating strains, and devel...
Genetic diversity, recombination, and codon-level selection of feline calicivirus ORF2 in Hokkaido (Japan) [0.03%]
日本北海道的杯状病毒ORF2基因遗传多样性、同源重组及密码子选择分析
Hiep Dinh Nguyen,Hitoshi Takemae,Shohei Yasui et al.
Hiep Dinh Nguyen et al.
To date, the genetic characteristics of feline caliciviruses (FCVs) in Hokkaido (Japan) have not been investigated. Here, 28 FCVs obtained in 2022-2023 from the Hidaka and Tokachi Districts were phylogenetically analyzed. Recombination brea...
Phylogenetic structure and clinical implications of carbapenemase-aerobactin (iuc) convergence in respiratory Klebsiella pneumoniae from a tertiary hospital in China, 2017-2023 [0.03%]
中国一家三级医院2017-2023年呼吸系统产碳青霉烯酶肺炎克雷伯菌的谱系结构及其临床意义：兼论产气杆菌素（iuc基因簇）与碳青霉烯耐药之间的关系
Han Zhou,Zhenchao Wu,Ping Yang et al.
Han Zhou et al.
Objectives: To characterise the phylogenetic structure and clinical implications of carbapenemase-aerobactin (iuc) convergence among respiratory Klebsiella pneumoniae isolates. ...
Evolutionary conservation and lineage-specific virulence repurposing of the core housekeeping gene ushA in Enterobacteriaceae [0.03%]
肠杆菌科的核心管家基因ushA在进化上被保护，并且其致病性在谱系中被重新利用
Benhao Han,Dongqing Xu,Jian Yang
Benhao Han
Objectives: This study aimed to characterize the genome-wide distribution, evolutionary trajectory, functional conservation of ushA across the Enterobacteriaceae family, and its phylogenomic association with the type III ...