Neurobiology of egg-laying behavior in Drosophila: neural control of the female reproductive system [0.03%]
神经元生物学：控制果蝇雌性生殖系统的产卵行为
Mehrnaz Afkhami
Mehrnaz Afkhami
Egg-laying is one of the key aspects of female reproductive behavior in insects. Egg-laying has been studied since the dawn of Drosophila melanogaster as a model organism. The female's internal state, hormones, and external factors, such as...
Memoir of the early years of the CSHL summer Drosophila neurobiology course: 1984-1985 [0.03%]
一个早期的冷泉港果蝇神经生物学暑期班回忆：1984-1985年
Ralph J Greenspan
Ralph J Greenspan
Oncogenic roles of long non-coding RNAs in essential glioblastoma signaling pathways [0.03%]
长非编码RNA在胶质母细胞瘤重要信号通路中的致癌作用
Mina Lashkarboloki,Amin Jahanbakhshi,Seyed Javad Mowla et al.
Mina Lashkarboloki et al.
Glioblastoma multiforme (GBM) is an aggressive and diffuse type of glioma with the lowest survival rate in patients. The recent failure of multiple treatments suggests that targeting several targets at once may be a different strategy to ov...
Mamiko Ozaki
Mamiko Ozaki
Barry Ganetzky
Barry Ganetzky
Carbamazepine responsive episodic dystonia and hallucination due to pyruvate dehydrogenase E2 (DLAT) gene mutation [0.03%]
丙酮酸脱氢酶E2（DLAT）基因突变所致的卡马西平反应性发作性肌张力不全和幻觉
Jasmine Policherla,Fatema J Serajee,Salman Rashid et al.
Jasmine Policherla et al.
Pyruvate Dehydrogenase (PDH) E2 deficiency due to Dihydrolipoamide acetyltransferase (DLAT) mutations is a very rare condition with only nine reported cases to date. We describe a 15-year-old girl with mild intellectual disability, paroxysm...
SORDD: mutation frequency and phenotype in predominantly axonal Charcot-Marie-Tooth disease of undefined genetic cause [0.03%]
特发性脱髓鞘型卡梅神经病的突变频率和表型分析
Annabelle Arlt,Esra Akova-Öztürk,Anja Schirmacher et al.
Annabelle Arlt et al.
Pathogenic, biallelic variants in SORD were identified in 2020 as a novel cause for autosomal-recessive Charcot-Marie-Tooth disease (CMT) type 2, an inherited neuropathy. SORD codes for the enzyme sorbitol dehydrogenase. Loss of this enzyme...
Martin G Burg
Martin G Burg
Exploring the evidence for mitochondrial dysfunction and genetic abnormalities in the etiopathogenesis of tropical ataxic neuropathy [0.03%]
探索线粒体功能障碍和遗传异常在热带性共济失调神经病发病机制中的证据
Shivani Sharma,Anita Mahadevan,Gayathri Narayanappa et al.
Shivani Sharma et al.
Tropical ataxic neuropathy (TAN) is characterised by ataxic polyneuropathy, degeneration of the posterior columns and pyramidal tracts, optic atrophy, and sensorineural hearing loss. It has been attributed to nutritional/toxic etiologies, b...
Personal essay of a rookie's journey with Bill Pak and his legacy: tales and perspectives on PI-PLC, NorpA and cyclophilin, NinaA - William L. Pak, PhD., 1932-2023: in memoriam [0.03%]
忆与比尔·pak博士共事的岁月：PI-PLC、NorpA和环孢菌素蛋白酶体肽酶的研究——追思威廉·L·pak博士（1932-2023）
Paulo A Ferreira
Paulo A Ferreira
The neurogenetics and vision community recently mourned William L. Pak, PhD, whose pioneering work spearheaded the genetic, electrophysiological, and molecular bases of biological processes underpinning vision. This essay provides a histori...