Global distribution of Xpert CT/NG assay Neisseria gonorrhoeae escape variants indicates sporadic emergence with limited clonality between 2016 and 2025 [0.03%]
2016年至2025年期间全球Xpert CT/NG测定耐药淋球菌分布状况表明该病属于偶发性疾病且不同地区间存在有限的克隆关系
Daniel Golparian,Maria Luiza Bazzo,Pamela Cristina Gaspar et al.
Daniel Golparian et al.
Screening of 54,837 gonococcal genomes identified 12 new variants lacking one (n = 9) or both (n = 3) of the Xpert CT/NG assay's gonococcal targets. In total, 17 diagnostic-escape variants occurred across five countries and multiple genomic...
Antibiotic consumption patterns in acute care hospitals: an integrated analysis using regression modelling combining data from two surveillance systems, Germany, 2022 [0.03%]
德国2022年急性护理医院抗生素消耗模式的综合分析：结合两个监测系统数据的回归模型分析
Karin Gröschner,Winfried V Kern,Tim Eckmanns et al.
Karin Gröschner et al.
BACKGROUNDTo enhance antibiotic stewardship and effectively address antimicrobial resistance (AMR), better understanding of subnational antibiotic consumption patterns is essential.AIMWe aimed to assess antibiotic consumption in Germany usi...
Effectiveness of long-acting monoclonal antibodies against laboratory-confirmed RSV in children aged < 24 months and hospitalised for severe acute respiratory infection, European pilot study, 2024 to 2025 [0.03%]
欧洲试点研究：长效单克隆抗体对2024至2025年因严重急性呼吸道感染住院的24个月以下儿童实验室确诊RSV的有效性
Camelia Savulescu,Iris Ganser,Nathalie Nicolay et al.
Camelia Savulescu et al.
We measured effectiveness of nirsevimab against laboratory-confirmed respiratory syncytial virus (RSV) infection in a test-negative case-control study among children aged < 24 months hospitalised for severe acute respiratory infection in th...
The rise of Candidozyma auris in Czechia: three clades, prosthetic joint infection and fluconazole resistance development, 2022 to 2024 [0.03%]
Czechia的耳念珠菌(Candidozyma auris)的崛起：三个谱系、人工关节感染和氟康唑耐药性发展，2022年至2024年
Bram Spruijtenburg,Jacques F Meis,Norman van Rhijn et al.
Bram Spruijtenburg et al.
BACKGROUNDCandidozyma auris has emerged globally as a major threat to public health due to its outbreak causing capacity and antifungal resistance. Outbreaks have proven difficult to control despite enhanced infection prevention measures. T...
Preliminary report: The most considerable outbreak of Legionnaires' disease in France in the last two decades, Albertville, September 2025 [0.03%]
法国阿尔贝维尔 legionnaires 病大暴发初步报告
Emmanuelle Vaissière,Audrey Merlet,Muriel Deher et al.
Emmanuelle Vaissière et al.
In September 2025, 50 laboratory-confirmed cases of Legionnaires' disease (LD) were identified in Albertville, in south-eastern France. Initially, 23 patients were only clinically diagnosed and only confirmed later due to limited sensitivit...
Emergence of vancomycin-resistant Enterococcus faecium vanA ST612 with reduced daptomycin susceptibility, Switzerland, 2018 to 2024 [0.03%]
2018至2024年瑞士出现具有达托霉素敏感性降低的万古霉素耐药肠球菌血清型ST612毒力 strains
Danielle Vuichard-Gysin,Andrea C Büchler,Dominique S Blanc et al.
Danielle Vuichard-Gysin et al.
We describe the emergence of vancomycin-resistant Enterococcus faecium (VREfm) vanA ST612 in Switzerland from 2018 to 2024 that resulted in a national outbreak investigation. This clone has predisposing genetic alterations associated with r...
Higher valency vaccines' impact on antimicrobial resistance rates in Streptococcus pneumoniae causing invasive disease: a retrospective analysis based on national reference laboratory data, Belgium, 2018 to 2023 [0.03%]
基于国家参考实验室数据的回顾性分析：2018年至2023年比利时侵袭性肺炎链球菌所致抗菌药物耐药率的变化及高价次疫苗的影响
Helene Vermeulen,Lize Cuypers,Boudewijn Catry et al.
Helene Vermeulen et al.
BACKGROUNDFifteen- and 20-valent pneumococcal conjugate vaccines (PCVs) offer broader protection against invasive pneumococcal disease (IPD) than PCV13. Adopting these vaccines may result in decreasing IPD incidence, antibiotic use and anti...
Design and implementation of blood donor sample bioarchives to enhance preparedness for emerging and pandemic pathogens in England [0.03%]
英格兰血液捐赠者样本生物档案的设计与实施，以增强应对新兴和大流行病原体的准备状态
Shannah Secret,Peter Simmonds,Janie Olver et al.
Shannah Secret et al.
New and emerging infections with blood-borne pathogens pose an ongoing threat to the safety of blood transfusions and transplants. Bioarchives of stored blood donor samples represent a valuable pathogen screening resource for both ensuring ...
Post-authorisation experience and reported adverse events following use of a virus-like particle chikungunya vaccine, United States and Germany, up to August 2025 [0.03%]
美国和德国寨卡病毒样颗粒疫苗上市后使用经验及疑似预防接种异常反应监测（2017年8月-2025年8月）
Benedetto Simone,Florian Lienert
Benedetto Simone
Older adults are at increased risk of severe chikungunya. Some countries advise against vaccinating ≥ 60 or ≥ 65-year-olds with the licenced live-attenuated vaccine (CHIKV LA, IXCHIQ), following severe adverse event (SAE) reports. A virus...
Outbreak of invasive meningococcal disease caused by a meningococcus serogroup B expressing a rare porA genosubtype (19-54, 15), Spain, March to April 2024 [0.03%]
2024年3月至4月西班牙发生罕见porA基因亚型（19-54，15）的脑膜炎球菌血清群B引起的侵袭性脑膜炎双球菌病暴发
Raquel Abad,Carmen Navarro,Cristina García-Amil et al.
Raquel Abad et al.
In Spain during March-April 2024, an outbreak of invasive meningococcal disease (IMD) occurred in four young adults, exhibiting high case fatality with two deaths. Cases 1 and 4 were confirmed by isolation of Neisseria meningitidis from blo...