Alignment of histological and polarimetric large-scale imaging for brain tissue characterization [0.03%]
基于全脑组织的大规模光学切片与偏振成像的融合技术
Éléa Gros,Omar Rodríguez-Núñez,Stefano Moriconi et al.
Éléa Gros et al.
Significance: Mueller polarimetric imaging shows great promise for differentiating neoplastic from healthy brain tissue during neurosurgery. However, validating algorithmic approaches is limited by the scarcity of substan...
Improving vascular retention of indocyanine green for in vivo two-photon microscopy using liposomal encapsulation [0.03%]
使用脂质体包裹技术改善近红外荧光探针ICG的体内滞留性能用于双光子成像研究
Alankrit Tomar,Noah Stern,Tyrone Porter et al.
Alankrit Tomar et al.
Significance: Two-photon microscopy is widely used for in vivo imaging of vasculature in rodents and requires the labeling of blood plasma with fluorescent dyes such as indocyanine green (ICG). However, a major limitation...
Integrating optical coherence tomography and bioluminescence with predictive modeling for quantitative assessment of methicillin-resistant S. aureus biofilms [0.03%]
光学相干层析成像及生物发光与预测模型结合定量评估耐甲氧西林金黄色葡萄球菌生物被膜
Valentin V Demidov,Olivia P Jackson,Natalia Demidova et al.
Valentin V Demidov et al.
Significance: Methicillin-resistant Staphylococcus aureus (MRSA) biofilm infections present a critical challenge in orthopedic trauma surgery and are notoriously resistant to systemic antibiotic therapy. Noninvasive, quan...
Prediction of the photodynamic therapy effect using digital breast phantoms from patients with breast cancer via Monte Carlo simulations [0.03%]
基于患者数据的数字乳腺模体的蒙特卡洛模拟预测光动力治疗效果研究
Yugo Minegishi,Yasutomo Nomura
Yugo Minegishi
Significance: Photodynamic therapy (PDT) agents activated by near-infrared (NIR) light have demonstrated effectiveness in animal studies. However, clinical trials in humans are lacking due to biocompatibility concerns. We...
Experimental method to assess depth sensing limits of inelastic scattering measurements using spatial-offset Raman spectroscopy imaging [0.03%]
基于空间偏移拉曼成像的非弹性散射测量深度感知限度的实验评估方法
Hugo Tavera,Guillaume Sheehy,Patrick Orsini et al.
Hugo Tavera et al.
Significance: The relationship between spatial offset and tissue sensing depth is not well understood in spatial offset Raman spectroscopy (SORS). Detection of the subsurface biochemical composition could improve clinical...
Asynchronous optical coherence elastography and directional phase gradient analysis [0.03%]
异步光学相干弹性图和方向相位梯度分析
Ginger Schmidt,Ryan McAuley,Brett E Bouma et al.
Ginger Schmidt et al.
Significance: The stiffness and compliance of biological tissues are key properties that often change in the presence of pathology, yet current shear wave elastography approaches using optical coherence tomography (OCT) f...
Mathematical modeling and analysis for tissue curvature correction in near-infrared spectroscopy imaging [0.03%]
近红外光谱成像中组织曲率矫正的数学模型与分析
Himaddri Shakhar Roy,Daniela Leizaola,Charles Policard et al.
Himaddri Shakhar Roy et al.
Significance: Near-infrared spectroscopy (NIRS) imaging modalities are used to provide noncontact measurements of tissue oxygenation in diabetic foot ulcers. However, the curved surface of the diabetic foot introduces ina...
Noninvasive continuous blood pressure prediction using FlexNIRS and machine learning during carotid endarterectomy [0.03%]
基于FlexNIRS和机器学习的颈动脉内膜剥脱术中无创连续血压预测
Zahra Einalou,Mehrdad Dadgostar,Kuan-Cheng Wu et al.
Zahra Einalou et al.
Significance: Continuous blood pressure (BP) monitoring is crucial for maintaining hemodynamic stability and complication prevention. Near-infrared spectroscopy photoplethysmography (NIRS-PPG) offers a noninvasive alterna...
Diffuse optical tomography system for acute traumatic brain injury in the intensive care unit: a prospective study on healthy volunteers [0.03%]
一种用于重症监护病房急性创伤性脑损伤的扩散光学层析系统：一项关于健康志愿者的研究
Mario Forcione,Antonio Maria Chiarelli,David Perpetuini et al.
Mario Forcione et al.
Significance: Invasive neuromonitoring hinders the application of diffuse optical tomography (DOT) to critically ill adults in the intensive care unit (ICU). ...
Intelligent laparoscopic grasper with hybrid neural networks for real-time vascular detection in minimally invasive surgery [0.03%]
基于混合神经网络的智能腹腔镜血管识别钳夹器
Pingping Wang,Yuting Huang,Chang Liu et al.
Pingping Wang et al.
Significance: We address the challenge of inadequate force feedback in laparoscopic surgery, which increases the risk of vessel injury. By integrating fiber Bragg grating (FBG) sensors with a laparoscopic grasper and empl...