Single-distance, phase-only frequency-domain NIRS for vascular oxygenation and tissue metabolism: a Monte Carlo simulation study [0.03%]
单距离、相位-only频率域NIRS用于血管氧合和组织代谢的研究：蒙特卡洛模拟研究
Muaaz Faiyazuddin,Haiyang Tang,Yiqing Hu et al.
Muaaz Faiyazuddin et al.
Significance: Frequency-domain near-infrared spectroscopy (FD-NIRS) currently enables absolute hemoglobin quantification but requires multidistance measurements of both amplitude attenuation and phase shifts. Notably, exi...
Multimodal microscope for optical coherence microscopy, tomography, vibrometry, and two-photon microscopy in the living mouse cochlea [0.03%]
用于活体小鼠耳蜗光学共焦显微镜、层析成像、振动测量和双光子显微镜的多模态显微镜
Clayton B Walker,Michael J Serafino,Patricia M Quiñones et al.
Clayton B Walker et al.
Significance: Our understanding of mechanotransduction in mammalian inner ears remains incomplete, in part due to imaging limitations: current systems cannot simultaneously provide high-resolution images needed for subcel...
Multiplane 2.5D microscopy for high-throughput high-resolution tissue imaging [0.03%]
一种用于高通量组织高分辨率成像的多平面二维半显微镜技术
Le-Mei Wang,Dhruvam Pandey,Wencai Zhang et al.
Le-Mei Wang et al.
Significance: Fast, high-throughput fluorescence imaging is essential for numerous biomedical applications, particularly in high-resolution volumetric tissue analysis. ...
Digital holographic microscopy for rapid bacteria segmentation and counting in microfluidic cartridges: basic considerations and limitations for diagnostic application [0.03%]
数字全息显微镜在微流体装置中快速细菌分割和计数的基本考虑与限制：诊断应用的局限性分析
Hussein Kamel,Julian Schmid,Moaaz Rauf Nizami et al.
Hussein Kamel et al.
Significance: Digital holographic microscopy (DHM) has proven effective for particle segmentation within a given volume, making it well-suited for rapid monitoring of bacterial growth in microfluidic cartridges-such as in...
Impact of sample handling protocols on soft tissue attenuation coefficient and morphology [0.03%]
样本处理方法对软组织衰减系数和形态的影响
Freja Hoeier,Gavrielle R Untracht,Amanda Oester Andersen et al.
Freja Hoeier et al.
Significance: The use of tissue attenuation coefficients as biomarkers for disease detection is rising. However, especially for ex vivo studies, sample handling methods can notably impact tissue optical attenuation proper...
Ultrathin lensed fiber-based manual scanning optical coherence tomography needle probe for the detection of the interproximal caries [0.03%]
用于检测邻面龋齿的超薄透镜光纤手动扫描光学相干层析成像针探头
Tong Wu,Yu Zhao,Jie He et al.
Tong Wu et al.
Significance: Interproximal caries detection is critical for effective dental treatment. We report an ultrathin lensed fiber-based manual scanning optical coherence tomography (OCT) needle probe to enables the direct imag...
Optical coherence elastography detects increased corneal stiffness in nonhuman primates with experimental glaucoma [0.03%]
光学相干弹性成像检测实验性青光眼非人灵长类动物眼中角膜僵硬度增加的现象
Amandeep Singh,Achuth Nair,Zhihui She et al.
Amandeep Singh et al.
Significance: Glaucoma is a leading cause of irreversible blindness, characterized by progressive optic nerve damage. Early detection of glaucoma is key to effective intervention, but an incomplete clinical understanding ...
Segmental airway adenocarcinoma-simulating phantom for endoscopic near-infrared optical coherence tomography [0.03%]
一段式气道腺癌内窥镜近红外光学相干层析仿形模体
Eric Brace,Alicia Fung,Adrian Tanskanen et al.
Eric Brace et al.
Significance: There is an unmet need for readily accessible imaging targets to verify whether devices can discriminate lesions from healthy tissue and identify sub-surface vasculature in the small airways. ...
Blood component analysis using mid-infrared photoacoustic spectroscopy based on ultrasound detection: glucose analysis trial [0.03%]
基于超声检测的中红外光电光谱法在血液成分分析中的应用：血糖检测试验
Kiiko Aiba,Saiko Kino,Yuji Matsuura
Kiiko Aiba
Significance: Noninvasive monitoring of blood components is important in daily health management. Conventional optical techniques such as attenuated total reflection (ATR) have limited penetration depth and sensitivity. P...
Anjelyka T Fasci,Maria A T Hoffman,Andrea L Smith et al.
Anjelyka T Fasci et al.
Significance: Understanding thermal effects on tissue optical properties is fundamental for optimizing laser-based medical interventions. We address the critical knowledge gap of temperature-dependent changes in porcine d...