Considerations for the use of targeted fluorescence contrast agents to detect circulating cancer cell populations with diffuse in vivo flow cytometry [0.03%]
靶向荧光对比剂检测活体内循环癌细胞群体的分散流式细胞术考虑因素
Joshua S Pace,Grace Matheson,Gauri Malankar et al.
Joshua S Pace et al.
Significance: Metastasis is a leading cause of cancer-related deaths. Disseminated circulating tumor cells (CTCs) through the bloodstream seed metastatic tumors at distant sites. Most methods for enumerating CTCs in human...
Erratum: Assessment of skin fibrosis in a murine model of systemic sclerosis with multifunctional optical coherence tomography (Erratum) [0.03%]
光学相干断层扫描在系统性硬化病的皮肤纤维化评估中的应用价值研究（刊误）
Harshdeep Singh Chawla,Yanping Chen,Minghua Wu et al.
Harshdeep Singh Chawla et al.
[This corrects the article DOI: 10.1117/1.JBO.30.3.036007.]. © 2026 The Authors.
Published Erratum
Journal of biomedical optics. 2026 Jan;31(1):019801. DOI:10.1117/1.JBO.31.1.019801 2026
Fraser T Watt,Efthymios Maneas,Desta Chan et al.
Fraser T Watt et al.
Significance: Freehand optical ultrasound (OpUS) is an emerging imaging modality that utilizes arrays of fiber-optic, photoacoustical ultrasound sources, and a single fiber-optic detector to perform pulse-echo ultrasound ...
Mona Shahsavari,Martine Kuiper,Mendel Engelaer et al.
Mona Shahsavari et al.
Significance: Intralipid® is widely used as a tissue-mimicking phantom due to its optical similarity to biological tissues, i.e., high scattering and low absorption of light. Accurate modeling of the optical behavior of ...
Artificial-intelligence-driven segmentation and analysis of microbial cells [0.03%]
基于人工智的微生物细胞分割和分析技术
Shuang Zhang,Carleton Coffin,Karyn L Rogers et al.
Shuang Zhang et al.
Significance: Understanding microbial growth and morphology at the single-cell level is essential for studying microbial physiology, providing valuable insights for research and biotechnology. However, existing workflows ...
Two-step regression analysis approach to assess burn wound severity using spatial frequency domain imaging [0.03%]
基于空间频率域成像的烧伤伤口严重程度评估的两步回归分析方法
Thinh Phan,Christopher A Campbell,Gordon T Kennedy et al.
Thinh Phan et al.
Significance: Prompt care is essential for burn wound recovery. Spatial frequency domain imaging (SFDI) has previously shown promise in predicting healing outcomes across burn severity grades. This study builds on that by...
Phasor-based FLIM analysis of NAD(P)H and FAD autofluorescence for label-free bacterial classification [0.03%]
基于相位的FLIM分析NAD(P) H和FAD自发荧光以实现无标签细菌分类
Piet Dyrøy,Julius Heitz,Hauke Studier et al.
Piet Dyrøy et al.
Significance: Bacterial contamination poses significant risks, particularly in medical settings, where timely identification is crucial for effective treatment. Traditional diagnostic methods often fail to provide rapid r...
Collagen microarchitecture from polarized light imaging: a biomechanics perspective [0.03%]
基于偏振光成像的胶原微结构：一种生物力学视角
Miriam Bohlmann Kunz,Po-Yi Lee,Gaël Latour et al.
Miriam Bohlmann Kunz et al.
Significance: Collagen, the main load-bearing component in tissue, is present in all animals and forms a variety of networks from the fibrils, fibers, bundles, and lamellae into which it self-assembles. The collagen micro...
Longitudinal three-photon imaging for tracking amyloid plaques and vascular degeneration in a mouse model of Alzheimer's disease [0.03%]
用于阿尔茨海默病小鼠模型淀粉样蛋白斑块和血管退行性病变纵向三光子成像的追踪研究
Eline Stas,Mengke Yang,Simon Schultz et al.
Eline Stas et al.
Significance: Vascular abnormalities may contribute to amyloid-beta accumulation and neurotoxicity in Alzheimer's disease (AD). Monitoring vascular degeneration as AD progresses is essential. Three-photon fluorescence mic...
Improved imaging interfaces on a co-registered ultrasound and optical microscopy multiscale system [0.03%]
一种共注册的超声和光学显微多尺度系统的改进成像接口
Jonathan Hale,Nathan Cudworth,Renata Farrell et al.
Jonathan Hale et al.
Significance: Integrating ultrasound (US) with multiphoton microscopy (MPM) enables comprehensive tissue characterization by combining contrast mechanisms across spatial scales. However, prior implementations suffer from ...