Susan R Compton
Susan R Compton
Murine norovirus (MNV) causes subclinical chronic infections in adult immunocompetent mice and is endemic in many mouse colonies. The susceptibility of neonatal mice to MNV infection was investigated. Intestinal homogenates from Swiss Webst...
Deborah M Mook,Kimberly A Benjamin
Deborah M Mook
A breeding colony consisting of 250 different strains of mice was treated with the topical acaricide selamectin for the mouse fur mite Myocoptes musculinus, with no apparent ill effect, suggesting that this drug is safe for use in mice. To ...
The effects of depth of isoflurane anesthesia on the performance of mice in a simple spatial learning task [0.03%]
异氟醚麻醉深度对小鼠空间学习任务表现的影响
Ana M Valentim,Heber C Alves,I Anna S Olsson et al.
Ana M Valentim et al.
Studies on humans and rodents indicate possible long-term cognitive impairment after surgery or general anesthesia. The goal of this study was to evaluate the effect of various anesthetic concentrations on spatial learning in adult mice. Th...
Evaluation of saphenous venipuncture and modified tail-clip blood collection in mice [0.03%]
鼠类股静脉穿刺与改良的尾巴剪切采血法的效果评估
Omorodola I Abatan,Kathleen B Welch,Jean A Nemzek
Omorodola I Abatan
The purpose of this study was to evaluate the effects of 2 methods of blood collection in unanesthetized mice. The saphenous venipuncture method was compared with a modified tail-clip technique that requires minimal restraint. Mice were eva...
Evidence-based animal care: new contributions to our knowledge base and the need for more [0.03%]
基于证据的动物护理：扩大知识体系的新贡献和更多的需求
Linda A Toth,Susan Compton
Linda A Toth
Comparison of technicians' ability to detect clinical signs in rats housed in wire-bottom versus solid-bottom cages with bedding [0.03%]
实验员检测笼底类型及垫料的不同对大鼠临床症状的影响比较
Terry R Van Vleet,James W Rhodes,C Robbie Waites et al.
Terry R Van Vleet et al.
Rodent toxicology studies have historically been performed in wire-bottom cages, but the 1996 Guide for the Care and Use of Laboratory Animals recommends solid-bottom caging with bedding. Some investigators have expressed concern that chang...
Quantification, distribution, and possible source of bacterial biofilm in mouse automated watering systems [0.03%]
小鼠自动化饮水系统中细菌生物被膜的定量、分布及可能来源分析
Thomas R Meier,Carrie J Maute,Joan M Cadillac et al.
Thomas R Meier et al.
The use of automated watering systems for providing drinking water to rodents has become commonplace in the research setting. Little is known regarding bacterial biofilm growth within the water piping attached to the racks (manifolds). The ...
Ammonia and carbon dioxide concentrations in disposable and reusable ventilated mouse cages [0.03%]
一次性通风和可重复使用的小鼠笼中氨气和二氧化碳的浓度
Jerald Silverman,David W Bays,Sheldon F Cooper et al.
Jerald Silverman et al.
This study compares resuable and disposable individually ventilated mouse cages in terms of the formation of intracage CO2 and NH3. Crl:CD-1(ICR) female mice were placed in either disposable or reusable ventilated cages in a positive pressu...
Development and application of a novel environmental preference chamber for assessing responses of laboratory mice to atmospheric ammonia [0.03%]
一种新型环境偏爱情境箱的构建及应用：以测定实验室小鼠对大气氨浓度变化反应为例
Angela R Green,Christopher M Wathes,Theo G M Demmers et al.
Angela R Green et al.
A novel environmental preference chamber (EPC) was developed and used to assess responses of laboratory mice to atmospheric ammonia. The EPC features 1) a test chamber with 4 individually ventilated, mutually accessible compartments; b) aut...
Concentration and emission of airborne contaminants in a laboratory animal facility housing rabbits [0.03%]
兔动物实验室内的气溶胶浓度及排放量分布研究
Tara G Ooms,James E Artwohl,Lorraine M Conroy et al.
Tara G Ooms et al.
Characterization of animal housing conditions can determine the frequency of bedding and cage changes, which are not standardized from facility to facility. Rabbits produce noticeable odors, and their excreta can scald and stain cages. Our ...