Effect of chain length of imidazolium ionic liquids on the l-phenylalanine induced phospholipid vesicle membranes: Fluorescence lifetime imaging microscopy study [0.03%]
咪唑离子液体碳链长度对苯丙氨酸诱导的磷脂囊泡膜的影响：荧光寿命成像显微镜研究
Nanigopal Bera,Sandip Mondal,Arijit Maity et al.
Nanigopal Bera et al.
Phenylketonuria, a congenital metabolic defect, has been identified as a consequence of the formation of toxic l-phenylalanine fibrillar self-assembly under millimolar concentration in blood. Here, we have studied the influence of l-phenyla...
İshak Afşin Kariper,Nilgün Okşak,Dilek Bahar
İshak Afşin Kariper
Exosomes are one of the extracellular vesicles that are secreted by almost all cell types and body fluids. Because they are nanosized (30-200 nm), they can be used as natural nanovesicles. Exosomes have recently been preferred for their low...
Insight into the role of the chemical nature and length of the loop nucleobases in the folding of G-quadruplex by the antimalarial drugs at the DNA interface [0.03%]
抗疟药物在DNA界面上的作用机制研究：碱基的化学性质和长度对G-四链体折叠的影响
Asim Bisoi,Prashant Chandra Singh
Asim Bisoi
G-quadruplexes (G4) have been proposed as an alternative target for cancer therapy, as the folding of DNA sequences into stabilized G4 in the cancer microenvironment affects key biological functions. The antimalarial drugs, hydroxychloroqui...
Molecular mechanisms underlying the effects of urea and the structural dynamics of bovine serum albumin [0.03%]
尿素作用效应的分子机制及牛血清白蛋白结构动力学研究
Yanis R Espinosa,C Manuel Carlevaro,C Gastón Ferrara
Yanis R Espinosa
The disruption of protein structures by denaturants such as urea is well-documented, although the underlying molecular mechanisms are not yet fully understood. In this study, we employed molecular dynamics simulations to examine the effects...
Enhanced collagenogenesis on three-dimensionally printed titanium surfaces by human gingival fibroblasts: An in vitro study [0.03%]
人牙龈纤维细胞的三维打印钛表面上增强型胶原生成：体外研究
Vitor de Toledo Stuani,Isabela Sanches Pompeo da Silva,Gustavo Gonçalves do Prado Manfredi et al.
Vitor de Toledo Stuani et al.
The lack of cementum in peri-implant tissues leads to a deficiency in anchorage points for gingival collagen fibers. This arrangement is linked to reduced protective capabilities compared to teeth. Therefore, there is a pressing need to dev...
Bacterial motility in aqueous micro-environment with natural soil particles [0.03%]
含天然土壤颗粒水基微环境中的细菌运动性研究
Diksha Shrestha,Kishan Mahmud,Sam Mortenson et al.
Diksha Shrestha et al.
Bacterial motility is essential for navigating heterogeneous environments like soil, where it plays a key role in nutrient cycling, bioremediation, and overall soil health. Despite its importance, the interplay between bacterial motility an...
Time-of-flight secondary ion mass spectrometry investigation of the influence of ambient air exposure on the migration of brain lipids in a matrix commonly used in matrix assisted laser desorption ionization mass spectrometry imaging [0.03%]
飞行二次离子质谱法研究环境空气暴露对基质中脑脂质迁移影响的调查（该基质常用于矩阵辅助激光解吸电离质谱成像）
Thorsten Adolphs,Michael Bäumer,Richard E Peterson et al.
Thorsten Adolphs et al.
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) and time-of-flight secondary ion mass spectrometry (ToF-SIMS) imaging are established techniques for the imaging of biological samples. MALDI-MSI uses organic...
Integrative analysis of single-cell and bulk transcriptomics reveals necroptosis signatures and immune landscape in hepatoblastoma [0.03%]
单细胞和批量转录组集成分析揭示了肝母细胞瘤中的坏死性凋亡特征和免疫图谱
Weizhou Qiao,Yue Liu,Qinglong Kong et al.
Weizhou Qiao et al.
Hepatoblastoma (HB) is a rare and aggressive pediatric liver tumor with complex etiology. Although necroptosis has been implicated in various cancers, its role in HB remains unclear. This study aimed to investigate the involvement of necrop...
Spatial mapping of the conformational and mechanical properties of bacterial surface biopolymers [0.03%]
细菌表面生物高分子构象和力学性质的空间图谱
Asma Eskhan,Somayeh Ramezanian,Samuel Uzoechi et al.
Asma Eskhan et al.
Forces acting between an atomic force microscopy silicon nitride cantilever and the bacterial surface biopolymers of Escherichia coli or Pseudomonas putida were spatially probed in water. The interactions were fitted to a model of steric re...
Surface potential modulates fibronectin adsorption and molecular interaction on graphene-based materials [0.03%]
石墨烯材料表面电位调控纤连蛋白吸附及相互作用研究
Rohit,Rachayita Bharadwaj,Chandrashish Roy et al.
Rohit et al.
Protein interactions on graphene-based materials (GBMs) are predominantly governed by interphase surface properties such as surface chemistry and roughness; however, the critical role of surface potential (SP) in modulating these interactio...