Human osteoblast derived biochemical cues and microsurface topography modulate osteogenesis in vitro and in vivo [0.03%]
人骨细胞来源的生物化学信号和微表面形貌调节体内外成骨过程
Deepa Mishra,Anne Bernhardt,Michael Gelinsky et al.
Deepa Mishra et al.
Indirect co-culture, wherein two distinct cell types are cultivated within the same medium without direct contact, remains a relatively underexplored approach in biomaterials science for simulating physiological cell-cell interactions on ma...
Nilimesh Das,Tanmoy Khan,Soumya Chaudhury et al.
Nilimesh Das et al.
The efficiency of enzymatic proteolysis is often attributed to the properties of the enzyme itself, with the substrate typically viewed as a passive participant. In this study, we demonstrate that the conformational state of the substrate c...
Surface functionalization of polycaprolactone-based biomaterials: Good practice and pitfalls [0.03%]
聚己内酯基生物材料的表面功能化：良好实践与陷阱
Alexandra L Mutch,María Natividad Gómez-Cerezo,Lisbeth Grøndahl
Alexandra L Mutch
Poly(ɛ-caprolactone) (PCL) remains widely studied in biomaterials science and biomedical engineering due to its versatility and applicability in regenerating a range of tissues including bone, cartilage, neural, and cardiovascular. Due to ...
Effects of vacuum exposure on sample stability for mass spectrometry analysis [0.03%]
样品真空暴露对其质量稳定性的影响分析
Matija Lagator,Siyu Liu,C Logan Mackay et al.
Matija Lagator et al.
Mass spectrometry (MS) often requires vacuum conditions, which, while beneficial for analysis, can unpredictably alter sensitive samples. This study investigates the impact of prolonged vacuum exposure on the consistency and reliability of ...
Neha Paddillaya,Akshar Rao,Anshul Shrivastava et al.
Neha Paddillaya et al.
Mechanical properties of the extracellular matrix (ECM) modulate cell-substrate interactions and influence cellular behaviors such as contractility, migration, and proliferation. Although the effects of substrate stiffness on mechanobiology...
Jianling Mo,Haolu Shi,Kefeng Ren et al.
Jianling Mo et al.
Bioactive herbal extracts have garnered significant attention due to their multitarget regulation and low toxicity, yet their clinical applications are limited by poor solubility, low bioavailability, and insufficient targeting. This review...
Ángel Guillén-Cervantes,Francisco Hernández-Rosas,Blas Schettino-Salomón et al.
Ángel Guillén-Cervantes et al.
For this study, zeolite powder served as a substrate for inoculating Metarhizium robertsii to demonstrate the biocompatibility between the entomopathogenic fungus and the zeolite mineral, as the initial step in developing a biological contr...
Analytical methods to study the complex dynamics of biofilm-biomaterial interfaces [0.03%]
分析方法研究生物膜-生物材料界面的复杂动力学现象
Yunxing Li,Dipankar Koley
Yunxing Li
Biofilm-biomaterial interfaces have an important role in biofilm development and pose a critical challenge in healthcare, contributing to device failures and chronic infections that affect patient outcomes and healthcare economics. This rev...
Tryptophan-stabilized gold-manganese oxide nanocomposites for enhanced superoxide dismutase activity [0.03%]
色氨酸稳定的金-氧化锰纳米复合材料用于增强超氧化物歧化酶活性
Kanika Bharti,Kalyan K Sadhu
Kanika Bharti
Syntheses of gold-manganese oxide nanocomposites were attempted by a redox-mediated growth method under varying mild reaction conditions with amino acid as a stabilization agent; finally, the nanocomposites were applied for superoxide dismu...
Competitive adsorption and functional activity of fibrinogen on polyurethane biomaterials surfaces [0.03%]
纤维蛋白原在聚氨酯生物材料表面的竞争吸附及其功能活性
Li-Chong Xu,Christopher A Siedlecki
Li-Chong Xu
An immunological atomic force microscopy technique was used to recognize fibrinogen adsorption and functional activity on polyurethane biomaterial surfaces in the presence of other proteins. The amount of fibrinogen adsorbed on surfaces as ...