Polymer brushes for friction control: Contributions of molecular simulations [0.03%]
用于摩擦控制的聚合物刷：分子模拟的贡献
Mohamed A Abdelbar,James P Ewen,Daniele Dini et al.
Mohamed A Abdelbar et al.
When polymer chains are grafted to solid surfaces at sufficiently high density, they form brushes that can modify the surface properties. In particular, polymer brushes are increasingly being used to reduce friction in water-lubricated syst...
UV- and thermally-active small bi-functional gelator for creating gradient polymer network coatings [0.03%]
具有紫外和热活性的小型双官能凝胶因子用于制造梯度聚合物网络涂层
Pandiyarajan Chinnayan Kannan,Jan Genzer
Pandiyarajan Chinnayan Kannan
We present a versatile one-pot synthesis method for creating surface-anchored orthogonal gradient networks using a small bi-functional gelator, 4-azidosulfonylphenethyltrimethoxysilane (4-ASPTMS). The sulfonyl azide (SAz) group of 4-ASPTMS ...
Phase separation in polymer-based biomimetic structures containing planar membranes [0.03%]
含有平面膜的基于聚合物的生物模拟结构中的相分离
Maryame Bina,Flavien Sciortino,Agata N Mahrir
Maryame Bina
Phase separation in biological membranes is crucial for proper cellular functions, such as signaling and trafficking, as it mediates the interactions of condensates on membrane-bound organelles and transmembrane transport to targeted destin...
Differentiating interactions of antimicrobials with Gram-negative and Gram-positive bacterial cell walls using molecular dynamics simulations [0.03%]
利用分子动力学模拟区分抗生素与革兰氏阴性菌和革兰氏阳性菌细胞壁的相互作用
Rakesh Vaiwala,Pradyumn Sharma,K Ganapathy Ayappa
Rakesh Vaiwala
Developing molecular models to capture the complex physicochemical architecture of the bacterial cell wall and to study the interaction with antibacterial molecules is an important aspect of assessing and developing novel antimicrobial mole...
Modification of nitrile hydratase from Rhodococcus erythropolis CCM2595 by semirational design to enhance its substrate affinity [0.03%]
通过半理性设计修改邱氏红球菌(CCM2595)的腈水解酶以增强其底物亲和力
Li Wang,Baocheng Cui,Keyuan Qiu et al.
Li Wang et al.
Nitrile hydratase (NHase, EC 4.2.1.84) is an excellent biocatalyst that catalyzes the hydration of nitrile substances to their corresponding amides. Given its catalytic specificity and eco-friendliness, NHase has extensive applications in t...
Smart DNA nanogel coated polydopamine nanoparticle with high drug loading for chemo-photothermal therapy of cancer [0.03%]
用于癌症化疗光热治疗的高载药量智能DNA纳米凝胶聚多巴胺涂层纳米粒子
Shiyu Zang,Xunxun Deng,Jiamian Wang et al.
Shiyu Zang et al.
A smart deoxyribose nucleic acid nanogel coated polydopamine nanosphere hybrid was designed for chemo-photothermal therapy of cancer. The nanohybrid showed good colloid stability, narrow size distribution, high drug loading, good biocompati...
Anchoring silver nanoparticles on nanofibers by thermal bonding to construct functional surface [0.03%]
通过热键合将银纳米粒子固定在纳米纤维上以构建功能表面
Bingjie Xu,Langfei Yang,Wei Pan et al.
Bingjie Xu et al.
Generally, the anchoring of inorganic nanoparticles onto the surface of fibers faces the problem of poor stability, which limits the wide application of nanoparticle functionalized fibers. Herein, nanofibers with shell-core structures were ...
Fine-tuned magnetic nanobubbles for magnetic hyperthermia treatment of glioma cells [0.03%]
磁热治疗胶质瘤细胞的精细调谐磁性纳米气泡
Bin Li,Yuexia Han,Yang Liu et al.
Bin Li et al.
Magnetic nanoparticle (MNP) induced magnetic hyperthermia has been demonstrated as a promising technique for the treatment of brain tumor. However, lower heating efficiency resulting from low intratumoral accumulation of magnetic nanomateri...
Shape-dependent gold nanoparticle interactions with a model cell membrane [0.03%]
形状依赖的金纳米粒子与细胞膜模型的相互作用
Thaddeus W Golbek,Bryan J Harper,Stacey L Harper et al.
Thaddeus W Golbek et al.
Customizable gold nanoparticle platforms are motivating innovations in drug discovery with massive therapeutic potential due to their biocompatibility, stability, and imaging capabilities. Further development requires the understanding of h...
Composition controls soft hydrogel surface layer dimensions and contact mechanics [0.03%]
组成控制软水凝胶表面层的尺寸和接触力学特性
Christopher L Johnson,Alison C Dunn
Christopher L Johnson
Hydrogels are soft hydrated polymer networks that are widely used in research and industry due to their favorable properties and similarity to biological tissues. However, it has long been difficult to create a hydrogel emulating the hetero...