Adenosine Concentration Determination for in Vitro Tumor Microenvironment Simulation [0.03%]
体外肿瘤微环境模拟的腺苷浓度测定
Chun Chen,Chuanpeng Yang,Shuning Hu et al.
Chun Chen et al.
Objectives: We aimed to investigate the concentration of adenosine (ADO) in the tumor microenvironment (TME), focusing on its potential to modulate tumor cells and natural killer (NK) cells, thereby facilitating tumor imm...
Mesua ferrea L. extract Attenuates Angiogenesis Through HIF-1α and WNT Mediated Blockage of VEGF/Angiopoietin Axis [0.03%]
MESUA FERREA L. 提取物通过HIF-1α和WNT介导的VEGF/血管生成素轴阻滞来抑制血管生成
Fengwei Zhang,Mohamed Farouk Elsadek,Shafqat Rasul Chaudhry et al.
Fengwei Zhang et al.
Objectives: The current study investigated angiogenesis-arresting attributes of Mesua ferrea oleo-gum resin extract and its underlying molecular mechanisms. ...
Combined Effects of Metformin, Quercetin, and Fractionated Gamma Irradiation on MiR-107-Mediated Brain Injury in HFD/STZ-Induced Diabetic Rats [0.03%]
二甲双胍、芸香素和分段γ射线辐照对高脂饮食(STZ小鼠糖尿病脑损伤的联合效应及MiR-107介导机制研究
Omayma A R Abozaid,Fatma S M Moawed,Hanaa F B Gabr et al.
Omayma A R Abozaid et al.
Objectives: MiR-107 upregulation represents a key target among the multiple pathways associated with T2DM. Given that drug combinations offer significant therapeutic potential, this study investigated the antidiabetic, antioxidant, and anti...
Ginsenoside Rk1 Enhances Chemosensitivity of Gastric Cancer Through Activating the AMPK/mTOR Pathway [0.03%]
人参皂苷Rk1通过激活AMPK/mTOR途径增强胃癌的化学敏感性
Yaqin Huang,Jian Wu,Li Zheng et al.
Yaqin Huang et al.
Objectives: Ginseng and its extracts have shown promising therapeutic effects on gastric cancer (GC). We aimed to investigate the functions and potential mechanisms of Ginsenoside Rk1 (Rk1) on GC. ...
Adaptive Response: A Scoping Review of Its Implications in Medicine, Space Exploration, and Beyond [0.03%]
适应性反应：对其在医学、太空探索等领域的潜在影响进行综述研究
Abolfazl Kanani,Julianna Krasowska,Krzysztof W Fornalski et al.
Abolfazl Kanani et al.
Objectives: Radiation Adaptive Response (AR) is a biological phenomenon in which exposure to low-dose radiation (LDR) enhances an organism's ability to withstand subsequent higher doses. This scoping review explores AR ac...
Utilizing of Seaweed for Eco-friendly Synthesis of Nickel Cobalt Nanoparticles and Assessment of its Cytotoxic Effects on Human Liver and Colon Cancer Cells [0.03%]
利用海藻进行绿色合成镍钴纳米颗粒并评估其对人类肝癌和结肠癌细胞的细胞毒性效应
Eman A Alanazy,Daoud Ali,Mohammed H A Almarzoug et al.
Eman A Alanazy et al.
In this study we used biosynthesis methods to create bimetallic nickel cobalt nanoparticles (Ni-Co NPs) utilizing seaweed. Before exposure to target cells, the characterization of Ni-Co NPs is done by UV-Vis spectrophotometry, EDX, SEM, TEM...
A Breakthrough on Modeling Cancer Prevention and Elimination by Low Radiation Doses [0.03%]
低剂量辐射预防和消除癌症的建模研究取得突破性进展
Bobby R Scott
Bobby R Scott
Background: Previously the author was unable to develop a formal mathematical characterization of his probability-based hormetic relative risk (HRR) model for cancer prevention/elimination by absorbed doses (D) of ionizin...
Magnetic Resonance Imaging and Computed Tomography May Carry Similar (but Very Low) Risks of Carcinogenesis [0.03%]
磁共振和计算机断层扫描可能具有类似的(但非常低的)致癌风险
Yuta Shibamoto
Yuta Shibamoto
In comparing magnetic resonance imaging (MRI) and computed tomography (CT), it is often stated thata significant advantage of MRI is its lack of ionizing radiation, which may contribute to carcinogenesis. This article questions whether this...
NEDD4-Mediated Endothelial-Mesenchymal Transition Participates in Radiation-Induced Lung Injury Through the ATM Signaling Pathway [0.03%]
NEDD4介导的内皮间质转化通过ATM信号通路参与放射性肺损伤
Yang Feng,Lirong Zhang,Youbin Zhang et al.
Yang Feng et al.
Objective: To elucidate the role of NEDD4 in ionizing radiation (IR)-induced endothelial-mesenchymal transition (EndMT) and its molecular mechanism in radiation-induced lung injury (RILI), given the unclear regulatory pat...
The Effect of Linarin on Relevant Inflammatory Markers in Ovalbumin-Induced Asthma Rat Models [0.03%]
黄酮醇苷Linarin对 ovalbumin诱导的大鼠哮喘模型相关炎症因子的影响研究
Kaihui Shen,Xiaohan Mei,Yawang Shao et al.
Kaihui Shen et al.
Objective: In the current work, we investigated and assessed the ability of the bioactive flavone linarin (LIN) to prevent asthma in the ovalbumin (OVA)-induced rat model. ...