Atomic Bomb Survivors Life-Span Study: Insufficient Statistical Power to Select Radiation Carcinogenesis Model [0.03%]
原爆受害者的寿命研究：无法选择辐射致癌模型的统计力度不足
Yehoshua Socol,Ludwik Dobrzyński
Yehoshua Socol
The atomic bomb survivors life-span study (LSS) is often claimed to support the linear no-threshold hypothesis (LNTH) of radiation carcinogenesis. This paper shows that this claim is baseless. The LSS data are equally or better described by...
Are Risks From Medical Imaging Still too Small to Be Observed or Nonexistent? [0.03%]
医学影像的风险仍然微乎其微到无法被观察或不存在吗？
Brant A Ulsh
Brant A Ulsh
Several radiation-related professional societies have concluded that carcinogenic risks associated with doses below 50-100 mSv are either too small to be detected, or are nonexistent. This is especially important in the context of doses fro...
Zhouli Liu,Wei Chen,Xingyuan He et al.
Zhouli Liu et al.
The hormetic responses of Lonicera japonica Thunb. to cadmium (Cd) stress were investigated in a hydroponic experiment. The present results showed that root length and total biomass dry weight increased in comparison with the control at low...
Adaption By Low Dose Radiation Exposure: A Look at Scope and Limitations for Radioprotection [0.03%]
低剂量辐射照射引起的放射防护适应性研究范围和限制展望
Ron E J Mitchel
Ron E J Mitchel
The procedures and dose limitations used for radiation protection in the nuclear industry are founded on the assumption that risk is directly proportional to dose, without a threshold. Based on this idea that any dose, no matter how small, ...
P Negri-Cesi
P Negri-Cesi
Brain development is an organized, but constantly adaptive, process in which genetic and epigenetic signals allow neurons to differentiate, to migrate, and to develop correct connections. Gender specific prenatal sex hormone milieu particip...
"You Can't Always Get What You Want" - Linearity as the Golden Ratio of Toxicology [0.03%]
“不足取所欲”——毒理学中的剂量效应关系宛如黄金分割
Aalt Bast,Jaap C Hanekamp
Aalt Bast
Referring to the Golden Ratio (i.e. expressed in the Fibonacci sequence) in nature and art, we conclude that toxicology knows its own Golden Ration, namely linearity. The latter seems imposed on pharmaco-toxicological processes that in fact...
From ischemic conditioning to 'hyperconditioning': clinical phenomenon and basic science opportunity [0.03%]
从缺血预适应到“过度预适应”：临床现象与基础研究机遇
Peter Whittaker,Karin Przyklenk
Peter Whittaker
Thousands of articles have been published on the topic of ischemic conditioning. Nevertheless, relatively little attention has been given to assessment of conditioning's dose-response characteristics. Specifically, the consequences of multi...
Pre-conditioning with low-level laser (light) therapy: light before the storm [0.03%]
低水平激光疗法的预处理：风暴前的光
Tanupriya Agrawal,Gaurav K Gupta,Vikrant Rai et al.
Tanupriya Agrawal et al.
Pre-conditioning by ischemia, hyperthermia, hypothermia, hyperbaric oxygen (and numerous other modalities) is a rapidly growing area of investigation that is used in pathological conditions where tissue damage may be expected. The damage ca...
Mark P Mattson
Mark P Mattson
Humans and their predecessors evolved in environments where they were challenged intermittently with: 1) food scarcity; 2) the need for aerobic fitness to catch/kill prey and avoid or repel attackers; and 3) exposure to biological toxins pr...
Post-conditioning and reperfusion injury in the treatment of stroke [0.03%]
缺血性卒中的后CONDITIONING和再灌注损伤
Roger Simon
Roger Simon
Endogenous mechanisms of protection against ischemia can be demonstrated in brain and other organs. The induction of such protection is via a response to sub lethal stress which induces "preconditioning". The preconditioned organ is then "t...