Peptidylprolyl Isomerase a Regulates DNA Damage Repair and Serves as a Prognostic Biomarker in Lung Adenocarcinoma [0.03%]
脯氨酰异构酶A调节DNA损伤修复并可作为肺腺癌预后生物标志物
Li Zou,Bixin Ren,Ying Wan et al.
Li Zou et al.
Background: This study investigated the role of peptidylprolyl isomerase A (PPIA) in lung adenocarcinoma (LUAD) using bioinformatics approaches and experimental validation. ...
Cnicin Attenuates Aluminium Chloride-Induced Neurodegeneration Through Antioxidant and Anti-Inflammatory Mechanisms [0.03%]
氯化铝诱导的神经退行性病变大鼠模型中CNTT通过抗氧化和抗炎机制发挥保护作用
Li Yu,Wardah A Alhoqail,Suresh Mickymaray et al.
Li Yu et al.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited disease-modifying therapies. Aluminium chloride (AlCl3)-induced neurotoxicity mimics key pathological features of AD, including...
Dose Reconstruction After a WD‒XRF Spectrometer Accident Using Minute-Rate TLD Measurements [0.03%]
基于微量热 luminescence 剂测量的WD-XRF 谱仪事故后个人受照剂量估算研究
Yiying Gao,Haoyu Wang,Ling He et al.
Yiying Gao et al.
Accurate dose estimation following radiation accidents remains challenging, particularly when personal dosimeter data are unavailable. This study presents a practical post-accident dose reconstruction approach based on minute-rate thermolum...
Integrating Network Pharmacology and Experimental Validation Reveals EGFR/PI3K/Akt Axis Mediates Ibrutinib-Induced Cardiotoxicity [0.03%]
基于网络药理学和实验验证的整合研究发现EGFR/PI3K/Akt信号轴介导伊布替尼诱导的心脏毒性
Yingxia Guan,Jiaqi Mei,Yuanqiao He et al.
Yingxia Guan et al.
Purpose: This study aims to systematically explore the molecular mechanism underlying ibrutinib-induced cardiotoxicity. Methods: Networ...
Mechanistic Insights Into Dose-Dependent Alleviation of Colorectal Cancer Through Artemisinin-Loaded Mesoporous Silica Nanoparticles in 1,2-Dimethylhydrazine-Induced Albino Wistar Rats [0.03%]
负载青蒿素的介孔硅纳米颗粒通过剂量依赖性缓解1,2-二甲基肼诱导的雪貂Wistar大鼠结直肠癌的机制研究
Fatima Zahid,Umair Ilyas,Sara Zahid et al.
Fatima Zahid et al.
Background: The current study investigates the suitability of encapsulating the Artemisinin-plant-originated lipophilic drug molecule into polyethylene glycol-coated mesoporous silica nanoparticles in a suitable dose regi...
Impact of a Short-Term High-Fat Diet on Lifespan and Tumorigenesis After Early-Life Exposure to Radiation [0.03%]
生命早期暴露于放射线后短期高脂肪饮食对寿命和致瘤性的影响
Yi Shang,Takamitsu Morioka,Yoshiko Amasaki et al.
Yi Shang et al.
Introduction: Children are highly susceptible to radiation's carcinogenic effects. Lifestyle, in particular, diet-induced obesity (DIO) is closely linked to cancer risk factors. Most prior studies, however, have concentra...
Hormesis as a Geometric Necessity of Bounded Adaptive Systems: Quantitative Predictions From First Principles [0.03%]
剂量反应曲线S形转换的几何必要性：有限适应系统 hormesis 的定量预测及第一原则公式推导
Daniel John Murray
Daniel John Murray
Objectives: To determine whether hormesis can be derived from the geometry of bounded adaptive biological endpoints, and whether the derivation yields quantitative predictions independent of curve fitting. ...
Friend or Foe: Dietary Restriction and Its Protective Effects on Responses to Ionizing Radiation [0.03%]
敌友难辨：饮食限制的放射防护效应及其作用机制
Yi Shang,Takanori Katsube,Nathupakorn Dechsupa et al.
Yi Shang et al.
Dietary restriction (DR) has been extensively investigated for its capacity to extend lifespan and mitigate age-associated pathologies. In the context of ionizing radiation (IR), DR-implemented through caloric reduction, selective nutrient ...
Retraction: Flucytosine and Amphotericin B Coadministration Induces Dose-Related Renal Injury [0.03%]
撤稿：氟胞嘧啶与两性霉素B合用导致剂量相关的肾损伤
[This retracts the article DOI: 10.1177/1559325817703461.]. © The Author(s) 2026.
miRNA-Targeted Herbal Compounds Against Gastric Precancerous Evolution in Chronic Atrophic Gastritis [0.03%]
胃黏膜萎缩性胃炎胃癌前病变的微卫星靶向中药研究
Chenlin Wang,Nan Zhang,Xiaoge Wang et al.
Chenlin Wang et al.
Gastric cancer (GC) ranks third globally in cancer mortality. It develops via a well-defined pathological sequence: normal gastric mucosa progresses sequentially to superficial gastritis, chronic atrophic gastritis (CAG), intestinal metapla...