Total Sanghuangporus vaninii Extract Ameliorates Cisplatin-Induced Glioma Cell Death by Regulating Ferroptosis and Inflammation [0.03%]
total桑黄酸性多糖通过调控铁死亡和炎症改善顺铂诱导的胶质瘤细胞凋亡
Yankai Xu,Jiesi Zhou,Xiaobin Zhou et al.
Yankai Xu et al.
Objectives: Ferroptosis is a distinct form of programmed cell death characterized by iron (Fe)-dependent oxidative stress and the accumulation of intracellular reactive oxygen species. Cisplatin (CPT), a chemotherapeutic ...
Causal Association Between Gut Microbiota, Plasma Metabolites, and Prostate Cancer: Two-Step Mendelian Randomization Study [0.03%]
基于两步孟德尔随机化研究的肠道微生物群、血浆代谢物与前列腺癌的因果关联
Junxiong Li,Jian Hou,Haolin Liu et al.
Junxiong Li et al.
Objectives: The specific role of metabolites in mediating the relationship between gut microbiota (GM) and prostate cancer (PCa) remains unclear. In this study, we utilized Mendelian randomization (MR) analyses to investi...
DMSO Protects Against Radiation-Induced Ovarian Injury by Preserving Mitochondrial Function and Alleviating DNA Damage [0.03%]
二甲基亚砜通过保存线粒体功能和减轻DNA损伤来预防放射引起的卵巢损伤
Jie Zhou,Renjun Peng,Zhongmin Chen et al.
Jie Zhou et al.
Background and purpose: Radiation-induced ovarian injury (RIOI) compromises the clinical utility of pelvic radiotherapy and reduces fertility in young female patients. Dimethyl sulfoxide (DMSO) exhibits antioxidant proper...
A Modern Odyssey of Prevention: Integrating Nutrition and Lifestyle in Radiation Mitigation- A Narrative Review [0.03%]
现代预防的奥德赛：辐射防护中营养和生活方式的整合-综述性文章
Polash Chandra Karmakar,Tusher- Al-Arafat,Cuihua Liu et al.
Polash Chandra Karmakar et al.
Ionizing radiation, though indispensable in medicine, energy, and space exploration, imposes complex biological stresses that disrupt redox homeostasis, inflammation control, and genomic integrity, ultimately contributing to fibrosis, immun...
Does Radioactivity From Nuclear Power Plants Raise the Risk of Cancer? Harvard School of Public Health: Yes. Biology: No [0.03%]
核泄漏致癌？ 哈佛大学说“是”，生物学说“不是”
Gregory Meyerson,Bill Sacks,James S Welsh
Gregory Meyerson
Efficacy and Safety of Fibroblast Activation Protein Targeted Radioligand Therapy for Advanced Solid Tumour: A Systematic Review and Meta-Analysis [0.03%]
靶向纤维激活蛋白的放射配体治疗晚期实体肿瘤疗效和安全性的系统评价和 meta 分析
Xiaoli Zhang,Jianpeng Cao,Xue Jiang et al.
Xiaoli Zhang et al.
Objective: Fibroblast activation protein (FAP) is a promising cancer theranostic target. While FAP-based diagnostics have proven highly accurate, the efficacy and safety of FAP-targeted radioligand therapy (FAP-RLT) for a...
The Effects of Tibetan Medicine Renqing Changjue Extracts on Cyclophosphamide-Induced Immunosuppression in a Mouse Model [0.03%]
藏药日宁常菊提取物对环磷酰胺所致免疫抑制小鼠的影响
Zhao Jiang,Xiumei Kong,Xiaoying Zhang et al.
Zhao Jiang et al.
Objectives: Renqing Changjue (RQCJ) is a form of Tibetan medicine recognized for its immunomodulatory effects. However, the underlying mechanisms through which it exerts these effects remain to be elucidated. ...
Daphnetin Ameliorates Pathological Damage in NK-92 Cells Induced by High-Glucose and High-free Fatty Acids [0.03%]
大花黄芩素通过减轻NK-92细胞高糖及游离脂肪酸诱导的病理损伤发挥胰岛保护作用
Xiaodong Zhong,Yijun Nie,Ningrui Wang et al.
Xiaodong Zhong et al.
Objectives: The present study aimed to characterize the protective role of daphnetin in attenuating HGHF-induced pathological injury in human NK-92 cells. ...
Mechanisms, Clinical Phenotype and Potential Risk Prediction for Cardiovascular Toxicity Induced by Tyrosine Kinase Inhibitors In Chronic Myeloid Leukemia [0.03%]
酪氨酸激酶抑制剂诱导的慢性髓性白血病心血管毒性的机制、临床表型及潜在风险预测模型
Hui Zheng,Chentong Huang,Zhanna Zhang et al.
Hui Zheng et al.
Tyrosine kinase inhibitors (TKIs) form the cornerstone of targeted therapy for chronic myeloid leukemia (CML), significantly improving patient prognosis. However, long-term use of TKIs, particularly second-generation (e.g., nilotinib) and t...
Optimal Dose of Lorundrostat in Uncontrolled Hypertension: A Dose Response Meta-Analysis [0.03%]
未控制高血压患者洛苏特罗的最佳剂量：剂量反应 meta 分析
Omar Abdullah Gill,Miguel Leonardo Salcedo Monterrubio,Ayeman Rashid et al.
Omar Abdullah Gill et al.
Background: Lorundrostat, an aldosterone synthase inhibitor, shows promise for hypertension management, though optimal dosing strategies remain poorly defined. ...