Salivary Circadian Gene Expression as a Molecular Indicator of Early Cognitive Impairment in Shift Workers: A Cross-Sectional Study of 300 Adults [0.03%]
轮班工人昼夜节律基因表达作为早期认知障碍分子标志物的横断面研究：300名成年人的研究结果
Adam Karim,Youssef Rayan,Ziad Amir et al.
Adam Karim et al.
This cross-sectional study explored the potential utility of salivary circadian gene expression as a non-invasive biomarker for early cognitive impairment in shift workers. Three hundred participants aged 25 to 55 were categorized into cogn...
Therapeutic Potential of products derived from Pluchea lanceolata for Alzheimer's Disease Treatment [0.03%]
来源于Pluchea lanceolata的阿尔茨海默病治疗药物的药理潜力
Asad Syed,Abdallah M Elgorban,Ali H Bahkali et al.
Asad Syed et al.
AD is a neurodegenerative disorder and is associated with the presence of amyloid-β plaques and neurofibrillary tangles leading to net loss of neurons, which demonstrates an urgent unmet need to develop new human health therapies based on ...
Integrin CD11b Alleviates Cerebral Ischemia/Reperfusion Injury via a Mechanism Involving Microglia/Macrophage Polarization [0.03%]
整合素CD11b通过介导小胶质细胞/巨噬细胞极化改善脑缺血再灌注损伤
Gui-Nan Jiang,Qiu-Yue Lin,Xiang-Bo An et al.
Gui-Nan Jiang et al.
The polarization of microglia/macrophages is crucial for maintaining the neuroinflammatory response during cerebral ischemia/reperfusion (I/R) injury. Integrin CD11b is implicated in the processes of neuroinflammation, immune regulation, an...
Cognitive and Behavioral Effects of Chronic Tartrazine Use in vivo: An Assessment Within and Above the Acceptable Daily Intake [0.03%]
体内慢性食用天然色素 tartrazine 的认知和行为效应评价：每日食用量在规定范围内及超出规定范围的评估
André Fellipe Freitas Rodrigues,Maisa Vitória Santos Sales,Gabriela Haro de Melo et al.
André Fellipe Freitas Rodrigues et al.
The use of dyes is a common practice in several industrial sectors to increase the attractiveness of the merchandise. Tartrazine is a synthetic yellow dye used in various food products; it contains an azo bond in its composition. The presen...
Correction: Urolithin A Enhances Tight Junction Protein Expression in Endothelial Cells Cultured In Vitro via Pink1-Parkin-Mediated Mitophagy in Irradiated Astrocytes [0.03%]
校正：尿石素A通过Pink1-Parkin介导的线粒体自噬增强体外培养的内皮细胞中紧密连接蛋白的表达（辐照星形胶质细胞中的作用）
Gengxin Lu,Junyu Wu,Zhihui Zheng et al.
Gengxin Lu et al.
Antiepileptic and Neuroprotective Biochemical Actions of Sabinene Prevent the Development of Pentylenetetrazol-Induced Seizures and Neuropsychiatric Comorbidities in Mice [0.03%]
α-细辛醚通过抗癫痫和神经保护作用预防戊四唑诱导的惊厥和神经精神共病小鼠模型发病
Grant Alumona,Benneth Ben-Azu,Daniel T Esuku et al.
Grant Alumona et al.
Epilepsy is a long-term neurological disorder that leads to disability with neuropsychiatric comorbidities. Studies have shown that neurochemical imbalances involved in the disease are linked to heightened oxidative and inflammatory pathway...
Serum Metabolomic Profiling in Possible Early-Stage Multiple Sclerosis: A Targeted 1H-NMR Comparison of OCB Type 1 and Type 2 Patterns [0.03%]
基于OCB类型1和类型2模式的1H-NMR针对早期多发性硬化症患者的血清代谢组学分析
Pınar Şengül,Ahmet Tarık Baykal,Mustafa Serteser
Pınar Şengül
Oligoclonal band (OCB) analysis in cerebrospinal fluid (CSF) remains a cornerstone for the early diagnosis of multiple sclerosis (MS), with recent criteria highlighting the κ-free light chain (κ-FLC) index as a sensitive marker of intrath...
Exploring Ciliary Mechanisms in the Causation of Hydrocephalus in Humans-Similarities and Differences from Animal Models [0.03%]
人类脑积水的鞭毛机制研究——与动物模型的异同点探索
Tina Nørgaard Munch,Paula L Hedley,Kim Gjerum Nielsen et al.
Tina Nørgaard Munch et al.
Hydrocephalus is a condition defined by excessive cerebrospinal fluid (CSF) relative to the brain volume. Congenital and infantile forms of hydrocephalus are both genetically and physiologically heterogenous. Among the candidate genes impli...
Ketogenic Diet Mitigates Age-Related Cognitive Decline and Neuroinflammation in Rats, While Antibiotics Exacerbate Brain Health Risks [0.03%]
生酮饮食可缓解大鼠的认知衰退和神经炎症，而抗生素会加重大脑健康风险
Oya Sayin,Rabia Ilgin,Erhan Caner Akkaya et al.
Oya Sayin et al.
The ketogenic diet (KD), a high-fat, low-carbohydrate regimen, has been shown to exert neuroprotective effects in various neurological models. This study explored how KD-alone or combined with antibiotic-induced gut microbiota depletion-aff...
Loss of COL20A1 in Schwann Cells Alters Regeneration of the Neuromuscular Junction and Locomotor Activity in Mice [0.03%]
胶质细胞COL20A1丢失影响小鼠神经肌肉突触的再生和运动能力
Robert Louis Hastings,William Boyce,Devin Juros et al.
Robert Louis Hastings et al.
Collagen type XX alpha 1 (COL20A1) was recently found to be highly concentrated in perisynaptic Schwann cells (PSCs), the synaptic glia of the neuromuscular junction (NMJ), suggesting that COL20A1 plays important roles in PSCs and at the NM...