Targeting Endoplasmic Reticulum Stress by Natural and Chemical Compounds Ameliorates Cisplatin-Induced Nephrotoxicity: A Review [0.03%]
天然和化学化合物靶向内质网应激改善顺铂引起的肾毒性：综述
Habibeh Mashayekhi-Sardoo,Ramin Rezaee,Fatemeh Yarmohammadi et al.
Habibeh Mashayekhi-Sardoo et al.
Cisplatin is a chemotherapeutic that dose-dependently causes renal complications such as decreased kidney function and acute kidney injury. The endoplasmic reticulum (ER) is responsible for calcium homeostasis and protein folding and plays ...
Follow-up Biomonitoring Study of Metal Exposure in Apprentice Welders in Montreal, Quebec, During Gas Metal Arc Welding (GMAW) [0.03%]
蒙特利尔魁北克期间气体金属电弧焊接（GMAW）的学徒焊工金属接触的后续生物监测研究
Jairo Buitrago-Cortes,Philippe Sarazin,Denis Dieme et al.
Jairo Buitrago-Cortes et al.
Welding activities are known to expose workers to metal fumes, but few studies have focused on assessing the internal exposure of apprentices in learning environments. This study aimed at determining internal doses of metals in apprentices ...
Tannic Acid Suppresses Ferroptosis Induced by Iron Salophene Complex in Kidney Cells and Prevents Iron Overload-Induced Liver and Kidney Dysfunction in Rats [0.03%]
绿原酸通过抑制铁沙ophone复合物诱导的肾细胞铁死亡防止铁过载致肝肾损伤
Indra Putra Taufani,Sri Tasminatun,Sabtanti Harimurti et al.
Indra Putra Taufani et al.
Iron toxicity intricately links with ferroptosis, a unique form of cell death, and is significantly influenced by lipid peroxidation. Despite its critical role in various diseases and drug development, the association between iron toxicity ...
Heavy Metal Biomonitoring in Cultured Rainbow Trout of the Black Sea and Risk Estimations on Its Consumption [0.03%]
黑海养殖虹鳟鱼的重金属生物监测及其食用风险评估
Levent Bat,Elif Arıcı,Ayşah Öztekin
Levent Bat
In recent years, the growing importance of fish species obtained through aquaculture, coupled with a decline in wild-caught fish, has raised concerns about the potential accumulation of pollutants in these fish. This work aimed to analyze t...
Agronomic Biofortification of Plants with Iodine and Selenium: A Potential Solution for Iodine and Selenium Deficiencies [0.03%]
植物富集碘和硒的农艺强化研究——缺碘和硒问题的一种潜在解决方案
Yesim Oztekin,Zehra Buyuktuncer
Yesim Oztekin
Iodine and selenium deficiencies are widespread both in developed countries and developing countries. The soil is the fundamental source of iodine and selenium for plants, and iodine and/or selenium-depleted soil restrains the cultivation o...
The ROS Mediates MCUb in Mitochondria-Regulated Apoptosis of TM4 Cells Induced by Titanium Dioxide Nanoparticles [0.03%]
ROS介导线粒体MCUb参与TiO2纳米粒子诱导TM4细胞凋亡中的作用机制研究
Chenhao Sun,Qianqian Wang,Pengfei Li et al.
Chenhao Sun et al.
Titanium dioxide nanoparticles (TiO2 NPs) can cause mitochondrial apoptosis of TM4 cells associated with reactive oxygen species (ROS) accumulation and Ca2+ overload, but the relations among these processes remain unclear. This study aimed ...
Distinct In Vitro Differentiation Protocols Differentially Affect Cytotoxicity Induced by Heavy Metals in Human Neuroblastoma SH-SY5Y Cells [0.03%]
不同的体外分化方案对重金属诱导的人神经母细胞瘤SH-SY5Y细胞毒性的影响不同
Jannatul Ferdous,Kiyotada Naitou,Mitsuya Shiraishi
Jannatul Ferdous
The SH-SY5Y cell line is widely used in neurotoxicity studies. However, the effects of inducing cell differentiation on the cytotoxic effects of heavy metals are unclear. Therefore, we investigated the effects of mercuric chloride (HgCl2), ...
Nutritional Impacts of Dietary Selenium, Iodine and their Interaction on Egg Performance, and Antioxidant Profile in Laying Longyuan Duck Breeders [0.03%]
饲粮硒、碘及其互作对岭南种蛋鸭产蛋性能及抗氧化机能的影响
Md Touhiduzzaman Sarker,Xiuguo Shang,Wei Chen et al.
Md Touhiduzzaman Sarker et al.
The present study aimed to optimize the combined effect of dietary selenium (SE) and iodine (ID) on the productive and reproductive performance and antioxidant capacity of Longyuan breeding ducks. A total of 288 Longyan duck breeders aged 2...
The Effect of Cuproptosis-Related Proteins on Macrophage Polarization in Mesothelioma is Revealed by scRNA-seq [0.03%]
单细胞RNA测序揭示库普西斯相关蛋白对间皮瘤巨噬细胞极化的影响
Jia-Xin Xu,Li-Jing Ma,Li-Ying Tu et al.
Jia-Xin Xu et al.
High invasiveness mesothelioma is a malignant tumor of the peritoneum or pleura. The effect of cuproptosis on mesothelioma (MESO) is still unknown, though. The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) datasets were u...
Yudong Wang,Qiushi Yan,Yang Shi et al.
Yudong Wang et al.
Copper is an essential trace element in animals and humans. However, excessive intake of copper can cause copper ions to accumulate in tissues and organs of animals, leading to copper toxicity. Copper ions induce apoptosis and autophagy thr...