Cadmium Exposure and Osteoporosis: A Spatially Contextualized Adverse Outcome Pathway Integrating Epidemiology, Toxicogenomics and Transcriptomics [0.03%]
镉暴露与骨质疏松症：整合流行病学、毒理基因组学和转录组学的具有空间背景意义的不良结果途径分析
Ye Tong,Baicheng Wan,Gaofeng Zeng et al.
Ye Tong et al.
Cadmium is an environmentally relevant metal toxicant associated with impaired bone health, but the mechanistic architecture linking cadmium exposure to osteoporosis remains insufficiently organized. We developed a cadmium-centered, adverse...
Boric Acid Combined with Venetoclax Induces Apoptosis in CLL Cell Lines via Caspase Activation and Oxidative Stress Modulation: In Vitro and In Silico Study [0.03%]
硼酸与维奈克拉克斯诱导慢性淋巴细胞白血病细胞系凋亡的体内和体外研究：通过半胱天冬酶活化和氧化应激调节
Dilek Nur Bestil,Hamdi Uysal
Dilek Nur Bestil
Chronic lymphocytic leukemia (CLL) is characterized by the clonal proliferation of mature B lymphocytes in the blood, bone marrow, and lymph nodes. The development of chemotherapy resistance has increased the need for novel and less toxic t...
Analyzing the Role of Essential Minerals in Neuropsychiatric Health: A Comparative Assessment of Depressed Versus Healthy Individuals [0.03%]
必需矿物质在神经精神健康中的作用分析：抑郁症患者与健康个体的比较评估
Maqbool Ahmed Soomro,Sanaullah Abbasi,Abdul Majid et al.
Maqbool Ahmed Soomro et al.
Background: Emerging evidence suggests a critical link between micronutrient deficiencies and mental health. This study investigated the relationship between serum levels of Magnesium (Mg), Iron (Fe), Zinc (Zn), and Selen...
Associations of Whole Blood Minerals and Trace Elements with Body Composition in Overweight and Obese Patients: A Retrospective Cross-Sectional Study [0.03%]
血清矿物质及微量元素与超重和肥胖患者机体成分关系的横断面研究
Zhiyi Zhou,Jing Chen,Yuanlan Chen et al.
Zhiyi Zhou et al.
Objective: To detect the levels of whole blood minerals and trace elements (calcium, iron, zinc, copper, magnesium) in overweight and obese patients, and explore their associations with body weight, body mass index (BMI) ...
Supranutritional Selenomethionine During Different Trimesters of Gestation in Beef Cows Alters Gene Expression Patterns in Peripheral Blood Mononuclear Cells at Parturition [0.03%]
母牛妊娠期不同孕期内灌服超营养硒甲硫氨酸可改变分娩时外周血单核细胞中的基因表达模式
Gerd Bobe,Joseph J Klopfenstein,T Zane Davis et al.
Gerd Bobe et al.
Selenium (Se) is an essential micronutrient. We have previously shown that supranutritional Se-yeast supplementation improves growth and immune function in Se-replete cattle and sheep despite limited impact on selenoprotein and oxidoreducta...
Terminalia arjuna Bark Nanosuspension Attenuates Fluoride-Induced Cardiotoxicity in Rats by Modulating Oxidative Stress, Inflammation and ACE Expression [0.03%]
Terminalia arjuna树皮纳米悬浮液通过调节氧化应激、炎症和ACE表达来减轻氟诱导的大鼠心毒性
Senthilkumar Keerthana,Palanisamy Sankar,Arivalagan Arivuchelvan et al.
Senthilkumar Keerthana et al.
Fluoride exposure through drinking water is an independent risk factor for cardiovascular disease. Terminalia arjuna is well known for its cardioprotective properties, including positive inotropic effects, hypolipidemic activity and coronar...
Statistical Comparison and Human Health Risk Assessment of Some Toxic and Trace Elements in Trachystemon orientalis (L.) G. Don (Boraginaceae) Grown in Türkiye Using ICP-OES and FAAS with Different Digestion Methods [0.03%]
使用ICP-OES和FAAS及不同消化方法对土耳其Trachystemon orientalis（L。）G. Don（硼学类）中一些有毒和微量元素的统计比较和人类健康风险评估
Aysen Kurt Cucu,Emirhan Ozdemir
Aysen Kurt Cucu
Trachystemon orientalis (L.) G. Don is an edible wild plant widely consumed as food and used in complementary medicine in Türkiye. This study aimed to determine the concentrations of some toxic and trace elements (Fe, Cu, Zn, Pb, Cd, and t...
Metal(loid) Occurrence, Possible Source Patterns, and Screening-Level Human Health Risk in Dried Fish from Thailand [0.03%]
泰国干鱼中金属(类金属)的存在形式、可能的来源模式及对人体健康的风险筛查水平
Pannraphat Takolpuckdee,Wattanee Boonwittaya,Somkid Tangkan
Pannraphat Takolpuckdee
Metal(loid)s are contaminants frequently detected in processed foods. This study investigated contamination of metal(loid)s, including arsenic, cadmium, chromium, copper, manganese, nickel, and zinc, in 8 types of dried fish obtained from m...
From Salt Deposits to the Dinner Table: A Systematic Review of Heavy Metal Contamination in Edible Salt; Sources, Limitations of Conventional Purification, Human Exposure, and Regulatory Gaps [0.03%]
从盐矿到餐桌：食盐中重金属污染的系统性综述；来源、传统净化方法局限性、人类暴露风险及监管空白点
Ali Nikmanesh,Shahram Saburirad,Alimohammad Yavarahmadi et al.
Ali Nikmanesh et al.
Edible salt is an essential component of the human diet and a critical vehicle for iodine fortification, yet it can also serve as a pathway for chronic dietary exposure to toxic heavy metals. Despite decades of research documenting metal co...
Assessment of Elemental Impurities and Associated Health Risks in Common Active Pharmaceutical Ingredients Using ICP-MS [0.03%]
基于ICP-MS的常用药物活性成分中痕量元素评估及其对人体健康的风险性分析
Adnan M Massadeh,Waad E Abu Diak,Yahya R Tahboub et al.
Adnan M Massadeh et al.
This study was intended to assess the concentration of 15 elemental impurities and associated health risks in 38 samples of active pharmaceutical ingredients (APIs) collected from different Jordanian pharmaceutical manufacturers using induc...