Association of Serum Lithium Levels with Insulin Resistance in Type-2 Diabetes Patients [0.03%]
锂化血清锂水平与2型糖尿病患者的胰岛素抵抗的关系
Pramod Kumar,Rasna Gupta,Manoj Yadav et al.
Pramod Kumar et al.
Insulin resistance arises from impaired insulin signaling, leading to reduced glucose uptake and the progression of type 2 diabetes mellitus. Experimental evidence indicates that lithium modulates insulin signaling pathways; however, its ro...
Combined Effects and Potential Mechanisms of Multiple Metals Exposure on Coronary Artery Disease in the US Population: An Integrated Epidemiological and Network Toxicology Study [0.03%]
美国人群冠心病的多金属暴露综合效应及潜在机制：整合流行病学与网络毒理学研究
Chaoyi Bian,Chuanting Wen,Kangkang Zhong et al.
Chaoyi Bian et al.
Coronary artery disease (CAD) emerged as a major global health burden, but the relationship between multiple metals exposure and CAD and its toxicological mechanism were not fully understood. We analyzed the data from the National Health an...
Role of H3K18 Acetylation in Cadmium-Associated Modulation of the Nrf2-Keap1/NF-κB Axis and Liver Fibrosis Progression [0.03%]
H3K18乙酰化在镉相关联的Nrf2-Keap1/NF-κB轴及肝纤维病进程调节中的作用
Yilin Liu,Yanling Zhou,Xiaole Liang et al.
Yilin Liu et al.
This study explores how chronic cadmium exposure induces H3K18 acetylation in hepatocytes, regulating the Nrf2-Keap1/NF-κB signaling pathway and promoting liver fibrosis. A CdCl₂-induced mouse model of liver fibrosis and hepatocyte injury...
Selenium Nanoparticles Inhibited H2O2-Induced Endothelial Cell Dysfunction by Alleviating Oxidative Stress [0.03%]
硒纳米颗粒通过减轻氧化应激抑制过氧化氢诱导的内皮细胞功能障碍
Na Li,Shengze Xiao,Wanru Yang et al.
Na Li et al.
Endothelial dysfunction is one of the important pathological bases of atherosclerosis, and cardiovascular diseases caused by atherosclerosis are the first major cause of human death. Our previous studies indicated that selenium nanoparticle...
Prenatal Cerium Exposure and Neural Tube Defect Risk: A Case-control Study in Shanxi, China [0.03%]
中国山西神经管缺陷的胚胎毒病因调查——铈元素的病例对照研究
Jing Wei,Fuyuan Yin,Zuqun Jin et al.
Jing Wei et al.
Neural tube defects (NTDs) exhibit a multifaceted etiology. Limited research has assessed the association between exposure to metallic and non-metallic elements and the incidence of NTDs at the elementomic level. Our study included 40 women...
Yang Ran,Ammara Khan,Xiaoyun Shen
Yang Ran
Molybdenum (Mo) is an essential trace element, but excessive exposure may exert toxic effects in ruminants. The pancreas plays a central role in post-ruminal digestion, yet the effects of high Mo exposure on pancreatic digestive function an...
Addition of Selenium to Silver Nanoparticles: An Approach to Enhance Their Antimicrobial and Biological Properties - Systematic Review [0.03%]
硒加入银纳米颗粒以增强其抗菌和生物学性能-系统综述
João Marcos Carvalho-Silva,Andréa Cândido Dos Reis
João Marcos Carvalho-Silva
The aim was to address the question, "Can the addition of selenium nanoparticles (SeNPs) to silver nanoparticles (AgNPs) enhance their antimicrobial and biological properties?" This systematic review followed the Preferred Reporting Items f...
Glutathione/Selenite Interaction Products as Potent Vascular Smooth Muscle Tone Modulators with Antihypertensive Effects in Spontaneously Hypertensive Rats [0.03%]
谷胱甘肽/亚硒酸盐作用产物作为潜在的血管平滑肌张力调节剂及 SHR 模型中的降压剂
Lenka Tomasova,Peter Balis,Marian Grman et al.
Lenka Tomasova et al.
Selenium is an essential trace element important for human health and its deficiency is typically compensated through dietary supplementation, including selenite (SeO32-). In biological systems, SeO32- undergoes multistep reduction, generat...
Developmental Toxicity of Lead and Copper in Chick Embryos: Morphometric and Histological Assessment of In Ovo Exposure [0.03%]
基于鸡胚胎的铅和铜的发育毒性效应及体内暴露剂量反应关系研究
Aima Iram Batool,Noor Fatima,Muhammad Fayyaz Ur Rehman et al.
Aima Iram Batool et al.
Heavy metals are widely recognized as potent teratogenic agents capable of inducing congenital malformations by disrupting normal embryonic development. The present study investigated the teratogenic potential of lead (Pb) and copper (Cu) o...
Risk of Zinc Deficiency from Urinary Zinc Loss Induced by Antihypertensive Drugs: A Narrative Review [0.03%]
降压药诱导的尿锌丢失导致锌缺乏的风险：一篇叙事综述
Zahra Bahadoran,Farhad Hosseinpanah
Zahra Bahadoran
Antihypertensive medications exhibit heterogeneous effects on zinc homeostasis, with potential clinical implications for patients at risk of zinc deficiency (ZnD). This review summarizes the effects of antihypertensive medications on zinc h...