Unveiling the Bio-corona Fingerprinting of Potential Anticancer Carbon Nanotubes Coupled with D-Amino Acid Oxidase [0.03%]
潜在抗肿瘤碳纳米管结合D型氨基酸氧化酶的生物冠指纹识别
Marta Boreggio,Elena Rosini,Cristian Gambarotti et al.
Marta Boreggio et al.
The oxidation therapy, based on the controlled production of Reactive Oxygen Species directly into the tumor site, was introduced as alternative antitumor approach. For this purpose, d-amino acid oxidase (DAAO) from the yeast Rhodotorula gr...
Expression, Purification, Structural and Functional Characterization of Recombinant Human Parvulin 17 [0.03%]
人重组Parvulin 17的表达、纯化及结构和功能鉴定
Alessandra Monti,Raffaele Ronca,Giuseppe Campiani et al.
Alessandra Monti et al.
Parvulins, peptidyl-prolyl isomerase enzymes (PPIase), catalyze the cis-trans isomerization of prolyl bonds in polypeptides, contributing to folding and function regulation of many proteins. Among Parvulins, Par17, exclusively expressed in ...
CRISPR/Cas9-Mediated Disruption of ZNF543 Gene: An Approach Toward Discovering Its Relation to TRIM28 Gene in Parkinson's Disease [0.03%]
基于CRISPR/Cas9的ZNF543基因敲除及该基因与帕金森病相关TRIM28基因的关系研究
Mohammad Hashemabadi,Hosseinali Sasan,Mojdeh Amandadi et al.
Mohammad Hashemabadi et al.
Genetic studies of familial forms of Parkinson's disease (PD) have shown that the ZNF543 gene is a candidate gene that operates relevant to this disease. However, until now, there is no evidence for ZNF543 gene function in PD, and mechanism...
Silencing a Myzus persicae Macrophage Inhibitory Factor by Plant-Mediated RNAi Induces Enhanced Aphid Mortality Coupled with Boosted RNAi Efficacy in Transgenic Potato Lines [0.03%]
植物介导RNAi沉默Myzus persicae巨噬细胞炎症蛋白诱导马铃薯转基因植株中蚜虫死亡率上升及RNAi效率增强
Shahid Murtaza,Bushra Tabassum,Muhammad Tariq et al.
Shahid Murtaza et al.
Myzus persicae causes considerable losses to crops as a major pest. The damage is direct by feeding and also partly indirect because it vectors plant viruses. The currently available control strategies rely on unsafe and nonecofriendly chem...
MiR-30a-3p Suppresses the Growth and Development of Lung Adenocarcinoma Cells Through Modulating GOLM1/JAK-STAT Signaling [0.03%]
miR-30a-3p通过调控GOLM1/JAK-STAT信号通路抑制肺腺癌细胞的生长和增殖
Dongxiao Ding,Yunqiang Zhang,Xuede Zhang et al.
Dongxiao Ding et al.
A considerable amount of people succumbs to lung adenocarcinoma (LUAD) due to its high incidence and mortality. This study attempted to reveal the impacts of GOLM1 on LUAD. This work analyzed GOLM1 expression in LUAD and normal tissue and s...
A Study on microRNAs Targeting the Genes Overexpressed in Lung Cancer and their Codon Usage Patterns [0.03%]
miRNA靶向肺癌过表达基因及其密码子使用特征的研究
Supriyo Chakraborty,Durbba Nath
Supriyo Chakraborty
As reported by WHO in 2018, there were 2.09 million victims of lung cancer and 1.76 million fatalities worldwide. Tobacco remains the biggest hazard in causing this lethal disease. To execute the computational analysis, the overexpressed lu...
MiR-199a-3p Restrains Foaming and Inflammation by Regulating RUNX1 in Macrophages [0.03%]
microRNA-199a-3p通过调节RUNX1限制巨噬细胞泡沫化和炎症反应
Mingxin Liu,Yiming Cao,Yu Hu et al.
Mingxin Liu et al.
MiR-199a-3p was reported decreased in serum of coronary heart disease patients and human atherosclerotic plaques. This study aims to investigate the roles of miR-199a-3p in atherosclerosis (AS). AS was induced in ApoE-/- mice via high fat d...
Heterologous Expression of LiSEP3 from Oriental Lilium Hybrid 'Sorbonne' Promotes the Flowering of Arabidopsis thaliana L [0.03%]
异源表达东方杂种百合 Sorbonne 的 LiSEP3 基因可促进拟南芥开花
Lei Cao,Dongying Liu,Fan Jiang et al.
Lei Cao et al.
The MADS-box gene family has multiple molecular and biological functions in plants. Here, the LiSEP3 gene of the MADS-box gene family of' 'Sorbonne' was obtained by homologous cloning using the petals of the flowering stage of Lilium Orient...
Kidney-Derived Methylated PAX2 Sequences in the Urine of Healthy Subjects as a Convenient Model for Optimizing Methylation-Based Liquid biopsy [0.03%]
健康人尿液中的肾脏来源的PAX2甲基化序列作为基于甲基化的液体活检优化的便捷模型
Xiang-Cheng Zhou,Qiu-Ping Chen,Jia-Jia Yuan et al.
Xiang-Cheng Zhou et al.
Although urine-based liquid biopsy has received considerable attention, there is a lack of a simple model to optimize assay parameters, including cell-free DNA (cfDNA) extraction, bisulfite modification, and bis-DNA recovery after conversio...
microRNA-148a in Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviates Cardiomyocyte Apoptosis in Atrial Fibrillation by Inhibiting SMOC2 [0.03%]
骨髓间充质干细胞衍生的外泌体中microRNA-148a通过抑制SMOC2缓解房颤中心肌细胞凋亡
Weijuan Zhang,Yilong Man,Zhanghu Chen
Weijuan Zhang
Exosomes-related microRNAs (miRNAs) have been considered to be the significant biomarkers contributing to the development of atrial fibrillation (AF). We observed the implicit mechanism of exosomes-miR-148a derived from bone marrow mesenchy...