Tailoring Corynebacterium glutamicum for Sustainable Biomanufacturing: From Traditional to Cutting-Edge Technologies [0.03%]
用于可持续生物制造的谷氨酸棒杆菌基因组工程：从传统到前沿技术
Eldin Kurpejović,Berna Sariyar Akbulut,Fatma Gizem Avci
Eldin Kurpejović
As the workhorse of industrial amino acid production, Corynebacterium glutamicum is the focus of this review, which provides a comprehensive overview of available techniques employed to engineer strains with desired traits. The review highl...
Phyto-Assisted Synthesis of Silver Nanoparticles (Ag-NPs) Using Delonix elata Extract: Characterization, Antimicrobial, Antioxidant, Anti-Inflammatory, and Photocatalytic Activities [0.03%]
利用Delonix elata提取物进行银纳米颗粒（Ag-NPs）的植物辅助合成：表征，抗菌，抗氧化，抗炎和光催化活性
Ragavendran Chinnasamy,Arumugam Priyadharsan,Chinnaperumal Kamaraj et al.
Ragavendran Chinnasamy et al.
The aim of present study mainly focuses on the green synthesis of silver nanoparticles (Ag-NPs) utilizing an aqueous extract of Delonix elata, which is an ecologically friendly and sustainable approach. The synthesized Ag-NPs were character...
Integrative Single-Cell and Spatial Transcriptomics Reveal Functional and Spatial Heterogeneity of Atrial and Ventricular Cardiomyocytes in the Heart [0.03%]
整合单细胞和空间转录组学揭示心脏心房和心室心肌细胞的功能和空间异质性
Lizhi Cao,Rui Chang,Xiaoying Wang et al.
Lizhi Cao et al.
Cardiomyocytes, pivotal for heart contractility, are categorized into atrial (aCM) and ventricular (vCM) subtypes, each playing distinct roles in modulating blood flow, electrical signal conduction, pump function, and energy metabolism. Rec...
Crystal Structure of Camel (Camelus dromedarius) Methemoglobin: A High Oxygen Affinity Lowland Species [0.03%]
单峰骆驼(阿拉伯种)亚铁血红素的晶体结构：一个高氧亲和力物种
Balasubramanian Moovarkumudalvan,Sathya Moorthy Ponnuraj,Ramya Ramadoss et al.
Balasubramanian Moovarkumudalvan et al.
Hemoglobin (Hb) is an important oxygen carrying protein inherent in erythrocytes facilitates exchange of oxygen and carbon dioxide from body tissues. Bioengineered synthetic erythrocytes with enhanced Hb proteins have been developed as effi...
Targeted Gene Delivery to MCF-7 Cells via Polyspermine-PEG-Glucose/DNA Nanoparticles: Preparation and Characterization [0.03%]
聚多胺-PEG-葡萄糖/DNA纳米颗粒制备及其介导基因靶向转染MCF-7细胞的研究
Sahar Mohajeri,Aytak Fathi Erdi,Hashem Yaghoubi
Sahar Mohajeri
Cationic polymers are positively charged polymers that have a high ability to electrostatically interact with negatively charged species, including nucleic acids. This property has led to the use of these polymers in various fields, includi...
Cloning and Expression Studies of Osmotin-Like Protein Gene from Solanum nigrum in Escherichia coli [0.03%]
家菊柳渗透素类似蛋白基因的克隆及在大肠杆菌中的表达研究
Muhammad Zafar Saleem,Fatima Arshad,Nauman Ahmad et al.
Muhammad Zafar Saleem et al.
Plants face various biotic and abiotic stresses, necessitating the activation of defense mechanisms, including pathogenesis-related (PR) proteins. Osmotin-like proteins (OLPs), belonging to the PR-5 family, play a crucial role in plant defe...
Synthesis of ZIF-67 Nanoparticles for Camel Whey Protein Delivery: Promising Antioxidant, Anti-inflammatory, Anticancer Effects, and Anti-biofilm Activity [0.03%]
用于骆驼乳清蛋白递送的ZIF-67纳米颗粒合成： promising抗氧化，抗炎，抗癌功效和抑菌活性
D Hamad,Emad H M Hassanein,Shimaa H Salem et al.
D Hamad et al.
Camel whey protein (CWP) offers various health benefits, including immune enhancement, anti-inflammatory, anticancer, and antibacterial properties. It also possesses antioxidant activity. However, its limited efficacy and stability restrict...
Biosynthesis of Silver Nanoparticles Using Endophytic Clonostachys rosea ZMS27 from Medicinal Plant Anemarrhena asphodeloides and its Antagonistic Activity Against Superficial Pathogenic Fungi [0.03%]
内生菌玫瑰青霉ZMS27合成银纳米粒子及其对浅部真菌的拮抗活性研究
Weitao Kong,Jiaqi Li,Zhijiang Chen et al.
Weitao Kong et al.
Superficial fungal infections (SFIs) represent a serious threat to global public health. It is known that silver nanoparticles (AgNPs) are characterized by potent antimicrobial properties. However, the therapeutic potential of biosynthetic ...
Toward the Development of a Biosimilar Variant of Glucarpidase (Carboxypeptidase G2): Secretory Production, Optimization, and Immobilization [0.03%]
促进糖皮质激素类似物（羧肽酶G2）变体的发展：分泌生产，最优化和固定化研究
Fatemeh Moradbeygi,Mohammad Bagher Ghoshoon,Issa Sadeghian et al.
Fatemeh Moradbeygi et al.
Carboxypeptidase G2 (CPG2) detoxifies high-dose methotrexate in cancer or autoimmune therapies. Additionally, CPG2 activates prodrugs at the tumor site in engineered CAR-T cell therapy. Since CPG2 cleaves glutamate from the substrate, it al...
Resolution of a T1-Like Bacteriophage Outbreak by Receptor Engineering [0.03%]
利用受体工程解决T1-like噬菌体爆发事件
Katrina A Black,Julie V Nguyen,Jolene R Ramsey et al.
Katrina A Black et al.
Bacteriophage contaminations pose substantial risks to biomolecular production pipelines, and their resolution is especially difficult when the identity of the offending agent is unknown. We recently experienced an outbreak of Escherichia c...