Scopoletin: A Validated Protector against Cerulein-induced Acute Pancreatitis & Associated Lung Injury by Regulating PPAR- γ "A Multidimensional Approach" [0.03%]
scopoletin：通过调节PPAR-γ来对抗胰管素诱导的急性胰腺炎及联发肺损伤的有效保护者“多维度方法”
Subhashini Brahadeeswaran,Kiran Kumar Chitluri,Leema George et al.
Subhashini Brahadeeswaran et al.
Our previous study established the effectiveness of scopoletin (SC) in protecting mice against acute pancreatitis (AP) induced by cerulein and subsequent pulmonary injury. However, the precise molecular mechanisms underlying SC protective e...
Molecular Investigation of FIKK Kinase Family to Develop PCR-Based Diagnosis of Plasmodium falciparum [0.03%]
FIKK激酶家族的分子研究及PCR诊断方法开发研究《恶性疟原虫》
M Rajendra Prasad,Vishal Trivedi
M Rajendra Prasad
Accurate malaria diagnosis is crucial for effective disease management as different Plasmodium species require specific treatment regimens. Current detection methods have limitations related to sensitivity and specificity. This is mainly du...
Design of a Golden Gate Cloning Plasmid for the Generation of a Chimeric Virus-Like Particle-Based Subunit Vaccine Against Porcine Circovirus Type 2 [0.03%]
用于生成嵌合病毒样颗粒基猪 circovirus 2 亚单位疫苗的黄金门克隆质粒的设计
Ana Del Socorro Hernández-Aviña,Luis Fernando Mendoza-Gómez,Xitlalli D Hernández-Mancillas et al.
Ana Del Socorro Hernández-Aviña et al.
Porcine circovirus type 2 (PCV2) is a pervasive pathogen in the swine industry, leading to a spectrum of disorders known as porcine circovirus associated diseases (PCVAD). The PCV2 Cap protein contains critical antigenic epitopes and is the...
Qiong Yuan,Yuhan Wang,Shan Hu et al.
Qiong Yuan et al.
Diabetic osteoporosis (DOP), a complication associated with diabetes mellitus (DM), is a metabolic bone disorder characterized by a reduction in bone mass per unit volume, impaired bone tissue microarchitecture, heightened bone fragility, a...
Mapping the Potential Genes and Associated Pathways Involved in Long COVID-Associated Brain Fog Using Integrative Bioinformatics and Systems Biology Strategy [0.03%]
基于整合生物信息学和系统生物学策略绘制与长新冠相关的脑雾的潜在基因及关联通路地图
Chiranjib Chakraborty,Manojit Bhattacharya,Abdulrahman Alshammari et al.
Chiranjib Chakraborty et al.
One of the recent emerging global health issues is long COVID. Among long COVID patients, long COVID-associated brain fog is an important area. We noted an immense gap in understanding the genes and associated pathways involved in long COVI...
Triple-Action Therapy: Combining Machine Learning, Docking, and Dynamics to Combat BRCA1-Mutated Breast Cancer [0.03%]
三管齐下的疗法：结合机器学习、对接和动力学对抗BRCA1突变型乳腺癌
Ashiru Aliyu Zainulabidin,Aminu Jibril Sufyan,Muthu Kumar Thirunavukkarasu
Ashiru Aliyu Zainulabidin
Breast cancer dominates women's mortality, and among other factors, mutations in the BRCA1 gene are significant risk factors. Several approaches are followed to treat the BRCA1 affected cancer patients. However, specific BRCA1 inhibitors ar...
Evaluation of Skin Color Supervision Genes in Chickpea Seeds by Multiomics [0.03%]
鹰嘴豆种子肤色监督基因的多组学评价研究
Yanming Ma,Lin Xu,Hongmei Zhuang et al.
Yanming Ma et al.
Seed samples of two types of chickpea (Cicer arietinum Linn.), including variety A (NRCGR-4452) and variety B (local varieties), with different seed colors, were collected every five days for a total of four times during the seed developmen...
A Simple and Cost-Efficient Method for the Production of Recombinant Horseradish Peroxidase in E. coli [0.03%]
一种简单且低成本的在大肠杆菌中生产重组辣根过氧化物酶的方法
Kimia Abraheh,Maryam Esmaeili,Nazanin Shans et al.
Kimia Abraheh et al.
Horseradish peroxidase (HRP) is a chromogenic glycoenzyme widely used in research, diagnostics, and therapeutics. Due to its high demand, various eukaryotic and prokaryotic expression systems have been employed for the production of recombi...
Seithikurippu R Pandi-Perumal,Konda Mani Saravanan,Sayan Paul et al.
Seithikurippu R Pandi-Perumal et al.
Whether it involves human subjects or non-human animals, basic, translational, or clinical sleep research poses significant ethical challenges for researchers and ethical committees alike. Sleep research greatly benefits from using diverse ...
Association Between the Expression of T Helper Type 17 Cell-Related Cytokines and Valve Damage in Rheumatic Heart Disease [0.03%]
风湿性心脏病患者中辅助型T淋巴细胞17相关细胞因子表达与瓣膜损害的关系研究
Caiyun Zhang,Zhenghua Xiao,Dongmei Yang
Caiyun Zhang
The study aimed to clarify the association between Th17 cell-related cytokine expressions and valve damage in rheumatic heart disease (RHD). Twenty RHD patients undergoing mitral valve replacement surgery were selected as the observation gr...