AAV Capsid Modification and Its Influence on Viral Protein Stoichiometry and Packaging Fitness: Current Understandings and Future Direction [0.03%]
腺相关病毒衣壳改造及其对病毒蛋白组成和包装特性影响的当前研究进展与未来方向
Dennis Makafui Dogbey,Stefan Barth
Dennis Makafui Dogbey
The field of gene therapy has witnessed significant advancements in the utilization of Adeno-associated virus (AAV) owing to its inherent biological advantages. Targeted AAV vectors are generated through genetic or chemical modification of ...
Effect of Elevated Temperature on Compressive Strength of MICCP and EICCP Biocemented Mortar [0.03%]
高温对MICCP和EICCP生物固化砂浆抗压强度的影响研究
Rishabh Junwale,Snigdha P Bhutange,Madhuwanti Latkar
Rishabh Junwale
Recently biocementation has got attention of many researchers worldwide as one of the most potent techniques for sustainable construction. Several studies have been carried out worldwide on biocementation by urea hydrolysis. Biocementation ...
Research Trends and Development Dynamics of qPCR-based Biomarkers: A Comprehensive Bibliometric Analysis [0.03%]
基于qPCR的生物标志物的研究趋势和发展动力学：全面文献计量分析
Li Liu,Ben-Rong Mu,Ya Zhou et al.
Li Liu et al.
Quantitative polymerase chain reaction (qPCR) is a vital molecular technique for biomarker detection; however, its clinical application is impeded by the scarcity of robust biomarkers and the inherent limitations of the technology. This stu...
M2 Microglia-Derived Exosomal miR-144-5p Attenuates White Matter Injury in Preterm Infants by Regulating the PTEN/AKT Pathway Through KLF12 [0.03%]
人源微胶质细胞来源的外泌体miR-144-5p通过KLF12调控PTEN/AKT信号通路减轻早产儿白质损伤
Zhaokui Zhu,Meng Meng,Sisi Mo et al.
Zhaokui Zhu et al.
Perinatal white matter injury (WMI), which is prevalent in premature infants, involves M2 microglia affecting oligodendrocyte precursor cells (OPCs) through exosomes, promoting OPC growth and reducing WMI. The molecular mechanism of WMI rem...
Exploring the Effects of Opioid-Related Drugs on the Clinical Outcome of Prostate Cancer Patients Via Integrated Bioinformatics Analysis [0.03%]
基于前列腺癌的整合生物信息学分析 opioid 类药物对前列腺癌预后的影响研究
Yunxuan Zhang,Yuenan Liu,Kailei Chen et al.
Yunxuan Zhang et al.
Opioids are the primary regimens for perioperative analgesia with controversial effects on oncological survival. The underlying mechanism remains unexplored. This study developed survival-related gene co-expression networks based on RNA-seq...
Exploration of the Biological Function of Ferroptosis in Bone Nonunion: An Analysis of Bioinformatics Combined Mendelian Randomization [0.03%]
铁死亡在骨不连中的生物学功能探索：生物信息学联合孟德尔随机化分析
Jun Yu,Kai Feng,Ming Yang et al.
Jun Yu et al.
To deeply investigate the mechanism of ferroptosis-related genes in the process of bone nonunion based on the GEO database. And using Mendelian randomization to explore the causal association of 15 trace elements with the occurrence of bone...
Nucleolin a Central Player in Host Virus Interactions and its Role in Viral Progeny Production [0.03%]
核糖体蛋白核仁结合蛋白在宿主病毒相互作用及其促进子代病毒产生中的作用机制研究
Ahsan Naveed,Rumaisa Umer,Ayzal Fatemah et al.
Ahsan Naveed et al.
Nucleolin (NCL) is a prevalent and widely distributed nucleolar protein in cells. While primarily located in the nucleolus, NCL is also found within the nucleoplasm, cytoplasm, and even on the cell surface. NCL's unique nature arises from i...
A Rapid PCR-LAMP Assay for the Early Detection of Lasiodiplodia theobromae from Basal Stem Rot-Infected Passion Fruit Plants [0.03%]
一种快速检测基部茎腐病感染的 passion fruit植物中Lasiodiplodia theobromae的方法
Ying Liu,Usman Rasheed,Bin Shan et al.
Ying Liu et al.
Lasiodiplodia theobromae is an emerging threat and the main pathogenic fungi associated with basal stem rot of passion fruit in Guangxi Zhuang Autonomous Region, China. Current pathogen identification protocols are labor-intensive and time-...
Panax Notoginseng Saponins Inhibit Apoptosis and Alleviate Renal Ischemia-Reperfusion Injury Through the ROCK2/NF-κB Pathway [0.03%]
三七总皂苷通过ROCK2/NF-κB信号通路抑制肾缺血再灌注损伤中肾脏细胞的凋亡作用研究
Liu Xin,Ning Kanghao,Li Jiacheng et al.
Liu Xin et al.
Renal ischemia-reperfusion injury (RIRI) is a primary cause of acute kidney injury (AKI), frequently resulting in high mortality rates and progression to chronic kidney disease (CKD). This study aimed to investigate the therapeutic potentia...
Biological Effects of Calceolarioside A as a Natural Compound: Anti-Ovarian Cancer, Anti-Tyrosinase, and Anti-HMG-CoA Reductase Potentials with Molecular Docking and Dynamics Simulation Studies [0.03%]
一种天然化合物假叶菊苷A的生物效应：抗卵巢癌、抗酪氨酸酶及抗HMG-CoA还原酶潜力的分子对接和动力学模拟研究
Liqin Chen,Dan Han,ChunYan Gu et al.
Liqin Chen et al.
One kind of hydroxycinnamic acid is calceolarioside A. Plantago coronopus, Cassinopsis madagascariensis, and other organisms for whom data are available are known to have this naturally occurring compound. IC50 values of Calceolarioside A f...