Gliomas with Downregulation of lncRNA SLC25A21-AS1 Carry a Dismal Prognosis and an Accelerated Progression in Cell Proliferation, Migration and Invasion [0.03%]
长链非编码RNA SLC25A21-AS1低表达的胶质瘤预后不良且细胞增殖、迁移和侵袭加快
Mingtao Zhu,Kunrong Li,Jing Zhang
Mingtao Zhu
Glioma is one type of primary intracranial carcinoma with a relatively poor prognosis. We investigated the level of SLC25A21-AS1 in gliomas and the association with survival and progression in patients with glioma. Specimens of gliomas from...
CCNB1, Negatively Regulated by miR-559, Promotes the Proliferation, Migration, and Invasion of Ovarian Carcinoma Cells [0.03%]
miR-559靶基因CCNB1通过调控卵巢癌细胞增殖、迁移和侵袭促进卵巢癌进展
Xiaowen Yang,Shilin Zhou,Chunyue Yang et al.
Xiaowen Yang et al.
Cyclin B1 (CCNB1) is regarded as an oncogene in multiple tumors. This work aims to investigate the expression, function, and related mechanisms of CCNB1 in ovarian carcinoma (OC). Three microarray datasets (GSE14407, GSE18520, and GSE54388)...
A Novel Chitosanase from Penicillium oxalicum M2 for Chitooligosaccharide Production: Purification, Identification and Characterization [0.03%]
一株解藻黄枝霉M2来源的新型壳聚糖酶的筛选、鉴定及产寡糖性能研究
Shining Cao,Pei Gao,Wenshui Xia et al.
Shining Cao et al.
This study discovered a novel chitosanase from Penicillium oxalicum M2 based on a new screening strategy. An extracellular chitosanase was isolated and purified from the fermentation broth of Penicillium oxalicum M2. A 19.34-fold purificati...
Jian Wang,Haijun Xia,Xiaolei Fan et al.
Jian Wang et al.
To evaluate the bone regeneration capacity of Zn-2Ag-0.04Mg alloy scaffold in vivo. Zn, Zn-2Ag and Zn-2Ag-0.04Mg scaffolds were implanted in the femur of New Zealand rabbits, and the degradation of the scaffolds and the regeneration of the ...
MiR-221-3p Facilitates Thyroid Cancer Cell Proliferation and Inhibit Apoptosis by Targeting FOXP2 Through Hedgehog Pathway [0.03%]
MiR-221-3p通过Hedgehog通路靶向FOXP2促进甲状腺癌细胞增殖并抑制凋亡
Wang Chang,Qing Chang,Haodong Lu et al.
Wang Chang et al.
Thyroid cancer (TC) is most often found in the endocrine system, the incidence of which has been on a continuous increase in recent years. For a better treatment of it, it becomes a pressing matter to further delve into the mechanism of TC ...
Enhanced Recombinant Protein Production of Soluble, Highly Active and Immobilizable PNGase F [0.03%]
一种增强型可溶、高活性和易于固相化的重组PNGase F蛋白表达体系
Noémi Kovács,Róbert Farsang,Márton Szigeti et al.
Noémi Kovács et al.
High resolution analysis of N-glycans can be performed after their endoglycosidase mediated removal from proteins. N-glycosidase F peptide (PNGase F) is one the most frequently used enzyme for this purpose. Because of the significant demand...
Sox9 Promotes Cardiomyocyte Apoptosis After Acute Myocardial Infarction by Promoting miR-223-3p and Inhibiting MEF2C [0.03%]
SOX9通过促进miR-223-3p和抑制MEF2C促进急性心肌梗死后心肌细胞凋亡
Lu Rui,Rui Liu,Huaping Jiang et al.
Lu Rui et al.
Acute myocardial infarction (AMI) is a severe and even fatal cardiovascular disease. The effect of transcription factors on AMI is intensively explored. Our experiment attempts to probe the role of Sox9 in cardiomyocyte apoptosis after AMI....
LncRNA NCK1-AS1 Promotes Malignant Cellular Phenotypes of Laryngeal Squamous Cell Carcinoma via miR-137/NCK1 Axis [0.03%]
长链非编码RNA NCK1-AS1通过miR-137/NCK1轴促进喉鳞状细胞癌的恶性表型
Lanlan Wan,Dongsheng Gu,Xin Jin
Lanlan Wan
Increasing evidence demonstrates that many long noncoding RNAs (lncRNAs) are implicated with the development of laryngeal squamous cell carcinoma (LSCC). As shown by bioinformatics analysis, lncRNA non-catalytic region of tyrosine kinase ad...
Christoph Steurer,Sarah Kerschbaum,Christina Wegrostek et al.
Christoph Steurer et al.
The heat shock response (HSR) pathway is a highly conserved rescue mechanism, which protects the cells from harmful insults disturbing the cellular protein homeostasis via expression of chaperones. Furthermore, it was demonstrated to play c...
Metabolic Engineering of Rice Cells with Vanillin Synthase Gene (VpVAN) to Produce Vanillin [0.03%]
携带香草兰醛合酶基因（VpVAN）的水稻细胞代谢工程用于生产香草兰醛
Sagar S Arya,Binod K Mahto,Meenu S Sengar et al.
Sagar S Arya et al.
Vanillin production by metabolic engineering of proprietary microbial strains has gained impetus due to increasing consumer demand for naturally derived products. Here, we demonstrate the use of rice cell cultures metabolically engineered w...