ASGR1 inhibitors, inflammation, and heart failure: A Mendelian randomization analysis [0.03%]
ASGR1抑制剂、炎症与心力衰竭：孟德尔随机化分析
Xingsheng Ye,Miaomiao Yang,Yinghao Hong et al.
Xingsheng Ye et al.
This study investigates the causal relationship between Asialoglycoprotein receptor 1 (ASGR1) inhibitors, inflammation, and heart failure (HF). Leveraging data from the Global Lipids Genetics Consortium (2021) and the UK Biobank, we identif...
Quantum Insights Into Fatty Acids, Antioxidant Mechanisms, and Molecular Docking Studies in Anacamptis papilionacea [0.03%]
用于研究_anacamptis_papilionacea_脂肪酸、抗氧化机制和分子对接的量子见解
Taşkın Basılı,Erdi Can Aytar,Mayker Lazaro Dantas Miranda et al.
Taşkın Basılı et al.
This study examines the antioxidant activities, fatty acid composition, cytotoxicity predictions, and endocrine-disrupting potential of metabolites from orchid methanolic-flower extracts. In silico analyses, including molecular docking, NCI...
Anthropometric indicators of obesity as screening tools for low high-density lipoprotein cholesterol in older adults: A cross-sectional study [0.03%]
老年人肥胖的人体测量指标作为低高密度脂蛋白胆固醇筛查工具的诊断价值：横断面研究
Yuri Silva de Souza,Lucas Dos Santos,Débora Jesus da Silva et al.
Yuri Silva de Souza et al.
Low levels of high-density lipoprotein cholesterol (HDL-C) increase the risk of cardiovascular events and mortality in older individuals. Developing cost-effective screening tools for identifying this condition in large populations is essen...
Efficacy and safety of low-dose atorvastatin plus ezetimibe for primary hypercholesterolemia: A randomized, double-blind, multicenter phase 3 trial [0.03%]
低剂量阿托伐他汀联合依折麦布治疗高胆固醇血症的多中心随机双盲Ⅲ期临床试验：有效性和安全性
Tae Oh Kim,Kyounghoon Lee,Jin-Man Cho et al.
Tae Oh Kim et al.
Studies have suggested that low-dose statin monotherapy may be insufficient for target LDL-C levels. In this randomized, double-blind, multicenter phase 3 trial, we evaluated the efficacy of combined ezetimibe and low-dose atorvastatin in 2...
Exogenous oxidized phytosterol may modulate linoleic acid metabolism through upregulation of fatty acid desaturase in rats [0.03%]
外源氧化植物甾醇通过上调脂肪酸脱氢酶调节大鼠亚油酸代谢
Tomonari Koyama,Kyoichi Osada
Tomonari Koyama
Previous in vitro studies have indicated that oxidized phytosterol (OPS) exhibits some toxicity; however, the harmful effects of OPS on fatty acid metabolism are not completely understood yet. Therefore, this study examined the effects of e...
Lipid and lipoprotein particle profiles in patients with type 2 diabetes mellitus: A comparative study between highlanders and lowlanders [0.03%]
2型糖尿病患者的脂质和脂蛋白颗粒谱特征：高原居民与低海拔地区居民比较研究
Chenghui Zhang,Rong Du,Suyuan Wang et al.
Chenghui Zhang et al.
The lipid profiles of highlanders and lowlanders differ. However, studies of the lipid profiles of patients with type 2 diabetes mellitus (T2DM) living at high altitudes are limited. This study aimed to compare lipid profiles and lipoprotei...
Lysophosphatidylcholine, rich in n-3 polyunsaturated fatty acids, inhibits leukotriene production by mouse mast cells [0.03%]
富含n-3多不饱和脂肪酸的溶血磷脂酰胆碱可抑制小鼠肥大细胞白三烯生成
Mikako Takasugi,Hirofumi Arai,Koki Sugimoto et al.
Mikako Takasugi et al.
In fishery industries, large amounts of byproducts are discarded during processing; therefore, their use as a source of n-3 polyunsaturated fatty acids (PUFAs) is beneficial. In this study, we evaluated the potential anti-allergic effect of...
Nonlinear association between plasma elaidic acid level and sleep complaints in US adults: NHANES 2009-2010 [0.03%]
等臂酸血浆水平与美国成年人睡眠障碍的非线性关系：2009-2010年国民健康和营养检查调查数据
Xin-Ying Liu,Kai Yao
Xin-Ying Liu
Poor sleep is linked to an increased risk of metabolic, cardiovascular, psychiatric, and neurodegenerative diseases, highlighting its emergence as a public health concern. Previous studies demonstrated the harmful effects of trans fatty aci...
Effects of a high-fat diet on gut microbiota and possible implications for bone health in male Wistar rats [0.03%]
高脂饮食对雄性大鼠胃肠道微生物群的影响及其对骨骼健康的可能影响
Fernanda Guedes Rodrigues,Milene Subtil Ormanji,Renata Meca et al.
Fernanda Guedes Rodrigues et al.
Diet plays an important role in the composition of gut microbiota. Emerging research suggests that bone homeostasis can also be influenced by the gut microbiota. The aim of this study was to assess possible alterations in gut microbiota in ...
Meta-regression of the relationship between dietary 18C n-3 concentration and enrichment of n-3 fatty acids in liver and breast muscle of broiler chickens [0.03%]
日粮中n-3系列18C脂肪酸浓度与肉鸡肝脏及胸肌中n-3系列脂肪酸富集量的元回归分析
Usman Ali,Ahmed El-Zenary,Kevin J Harvatine
Usman Ali
The long-chain n-3 fatty acids (FA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have human health benefits, and many experiments have investigated the ability of plant n-3 sources to enrich n-3 FA in broiler meat. A meta-regr...