Dietary Lard at 25% Fat Energy Level Enhances Adipose Tissue Browning and Gut Microbiota Remodeling in Mice Relative to Soybean Oil [0.03%]
与大豆油相比，膳食猪油以25％的脂肪能量比例增强小鼠的体脂褐变和肠道菌群重塑
Fangrui Guo,Liu Xu,Xiangyan Liu et al.
Fangrui Guo et al.
To examine the disparities in adipose tissue browning between diets rich in lard and soybean oil under low and recommended caloric intake conditions. In this study, sixty 8-week-old male C57BL/6J mice were randomly divided into four groups ...
Changes in Plasma Sphingolipid Metabolites Following Roux-En-Y Gastric Bypass in Women With Obesity and Type 2 Diabetes: A Pilot Metabolomic Cohort Study [0.03%]
代谢组队列研究：女性肥胖合并2型糖尿病患者胃旁路术前后血浆鞘脂代谢物的变化规律
Gabriela de Oliveira Lemos,Raquel Susana Torrinhas,Natasha Mendonça Machado et al.
Gabriela de Oliveira Lemos et al.
Although sphingolipids are key players in lipotoxicity and metabolic diseases, their response to bariatric surgery and their relation to metabolic improvement remain unclear. This pilot study investigated plasma sphingolipid remodeling afte...
Ginger (Zingiber officinale) and Black Pepper (Piper nigrum) Fixed Oil Sustain Hepatic and Renal Function: Insight From a Metabolic Disorder Rat Model [0.03%]
固定油 Ginger (Zingiber officinale)和黑胡椒 (Piper nigrum)维持肝功能和肾功能：代谢障碍大鼠模型的启示
Manasa Hassan Yashwanthkumar,Megha Manmohan Raj,Sai Kumar Somashekher et al.
Manasa Hassan Yashwanthkumar et al.
We report hepatic and renal parameters affected by fixed oil from ginger (Zingiber officinale) and black pepper (Piper nigrum) in male Wistar rats. Dyslipidaemia (hyperlipidemia) and diabetes were induced by feeding 35% saturated fat for 30...
Long-Chain Fatty Acid Beta-Oxidation Defects: A Case Series and Literature Review [0.03%]
长链脂肪酸β氧化缺陷：病例系列及文献综述
Juan Politei,Andrés Berardo,Esteban Calabrese et al.
Juan Politei et al.
Fatty acid beta-oxidation defects (FAOD) are a subgroup of lipid myopathies with heterogeneous presentations. Clinical presentation may manifest as muscular weakness, cramps, postexercise myalgias, and episodic rhabdomyolysis in children or...
Association Between the TyG Index and Liver Fat Content Measured by Quantitative CT in Individuals With T2DM: A Cross-Sectional Study [0.03%]
基于定量CT的非酒精性脂肪肝与TyG指数的相关性研究——横断面研究
Jie Zhang,Yan Ye,Xiangwei Li et al.
Jie Zhang et al.
The triglyceride glucose (TyG) index is increasingly recognized as a simple yet reliable surrogate marker of insulin resistance. This study aimed to explore the relationship between the TyG index and liver fat content (LFC) quantified via q...
ACSL1 Contributes to Metabolic-Associated Fatty Liver Disease by Mediating Arachidonic Acid Metabolism [0.03%]
ACSL1通过介导花生四烯酸代谢参与代谢相关脂肪性肝病
Meiao Tan,Zunming Zhou,Chong Peng et al.
Meiao Tan et al.
The precise involvement of ACSL1 in metabolic-associated fatty liver disease (MAFLD) pathogenesis remains unclear. To this end, we analyzed the effects of long-chain acyl-CoA synthase (ACSL1) on MAFLD. Analysis of GEO datasets showed that A...
Valproic Acid Exacerbates Lipid Accumulation in High-Fat Hepatocytes Induced by Oleic Acid: Insights From Lipidomic Analysis [0.03%]
脂质组学分析提示丙戊酸钠可加重棕桐酸诱导的肝细胞脂肪蓄积
Shansen Xu,Xianglei Ma,Lingli Huang et al.
Shansen Xu et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) and valproic acid (VPA)-induced hepatotoxicity both involve dysregulated lipid metabolism. However, the specific effects of VPA on lipid metabolism in the context of MASLD rem...
Sterol Metabolism in Ovariectomized Rats: Potential Roles of Campesterol and 4β-Hydroxycholesterol in Osteoporosis [0.03%]
卵巢切除大鼠的甾醇代谢：菜油甾醇和4β-羟基胆固醇在骨质疏松症中的潜在作用
Wenzhao He,Sayuri Eguchi,Sen Wang et al.
Wenzhao He et al.
Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue. Lipid metabolism disorders may contribute to osteoporosis in postmenopausal women. Phytosterols and oxysterols (OC) are involved in lipid me...
Effect of Dietary Oils on the Accumulation of Conjugated and Other Polyunsaturated Fatty Acids in Zebrafish Tissues [0.03%]
饲料油脂对斑马鱼组织共轭脂肪酸及其他多不饱和脂肪酸积累的影响
Apolline Goudmaeker,Anaïs De Simone,Éric Mignolet et al.
Apolline Goudmaeker et al.
Dietary polyunsaturated fatty acids (PUFA), including conjugated linolenic acids, are increasingly investigated for their potential health benefits. Zebrafish have emerged as a promising in vivo model for studying the metabolism and effects...
Cashew Nut Oil Improves Lipid Metabolism and Fat Liver Deposition in High-Fat Diet-Fed C57BL/6J Mice [0.03%]
花生酱改善高脂饮食喂养的C57BL/6J小鼠血脂代谢及脂肪肝沉积
Marcella Duarte Villas Mishima,Andressa Ladeira Bernardes,Carlos Alexandre Pinheiro et al.
Marcella Duarte Villas Mishima et al.
Cashew nut oil adds value to the production chain of this Brazilian oilseed. It is a good source of monounsaturated and polyunsaturated fatty acids and bioactive compounds, such as phenolics. This study investigated the effects of cashew nu...