Subtype-Specific Causal Effects of C16 and C24 Ceramides on Heart Failure: Evidence From Univariable and Multivariable Mendelian Randomization Analyses [0.03%]
基于单变量和多变量孟德尔随机化分析的C16和C24鞘氨醇脂肪酸亚型特异性因果效应在心力衰竭中的作用证据研究
Zeda Wang,Yakui Xue,Kaishan Han
Zeda Wang
Ceramides (Cer) are bioactive lipids implicated in cardiovascular disease (CVD), yet their subtype-specific causal effects remain unclear. We performed a two-sample Mendelian randomization (MR) analysis using publicly available GWAS summary...
First Report of Δ5,8,11,14,17-Octadecapentaenoic Acid (18:5n-1) in Diatoms (Bacillariophyceae: Thalassiosirales) [0.03%]
首次在硅藻中发现五顺式芥酸(18:5ω-1)
Ksenia Chadova
Ksenia Chadova
In this study, we report the first detection of a unique Δ5,8,11,14,17-octadecapentaenoic acid (18:5n-1) in six diatom species (Thalassiosirales). The fatty acid was detected by GC-MS and GC-FID analyses using nonpolar capillary column SH-...
Impact of Heated Versus Unheated Cooking Oil on Postprandial Vascular Function and Metabolism [0.03%]
加热与非加热的烹饪油对餐后血管功能和代谢的影响研究
Rosiered Brownson-Smith,Jo Bruce,Esmat Abbas et al.
Rosiered Brownson-Smith et al.
The impact of repeated heating of seed-based culinary oils on cardiometabolic health has not been well established. Heating oils to high temperatures (> 150°C) causes lipid peroxidation, thus generating potentially harmful compounds that m...
Compound-Specific Stable Isotope Analysis Improves the Association Between Dairy Fatty Acid Biomarkers and Dairy Intake: A Secondary Analysis [0.03%]
基于特定化合物的稳定同位素分析改善了乳脂酸类生物标志物与乳制品摄入关联性:二次分析
Camilla Parzanini,Marisa Soo,Shirley Vien et al.
Camilla Parzanini et al.
Increasing evidence suggests that dairy consumption may decrease the risk of chronic diseases. However, this association remains unclear due to methodological limitations. As a part of a secondary analysis, we used compound-specific stable ...
Lipid Profile in Primary Aldosteronism: Cross-Sectional and Post-Treatment Analyses [0.03%]
原发性醛固酮增多症的血脂谱:横断面和治疗后分析
Meriem Yazidi,Arige Abid,Chayma Bel Hadj Sliman et al.
Meriem Yazidi et al.
The relationship between primary aldosteronism (PA) and lipid metabolism remains controversial, with inconsistent findings reported in the literature. This study aimed to clarify PA's impact on the lipid profile using both a cross-sectional...
The Role of Obesity in the Association Between Alcohol Consumption and HDL-c Levels: Baependi Heart Study [0.03%]
酒精摄入与HDL-C水平的相关性中肥胖扮演的角色:Baependi心脏研究
Larissa Esthefani Barros Cirino,Divanei Zaniqueli,Oscar Geovanny Enriquez-Martinez et al.
Larissa Esthefani Barros Cirino et al.
Cardiovascular diseases (CVD) are a leading cause of global mortality, with dyslipidemia playing a central role in their pathogenesis. The influence of alcohol consumption on lipid profiles, particularly high-density lipoprotein cholesterol...
Maternal Fatty Acid Desaturase Indices in Early Pregnancy and Risk of Low Birth Weight [0.03%]
早期妊娠期母亲脂肪酸去饱和酶指标与新生儿低出生体重风险的关系
Juhi Nema,Karuna Randhir,Hemlata Pisal et al.
Juhi Nema et al.
Long chain polyunsaturated fatty acids are an important determinant of the birth weight of the baby. Studies have reported altered fatty acid desaturase indices (Δ5 and Δ6 desaturases) from early pregnancy in women with pregnancy complica...
Association Between Neutrophil-To-HDL Cholesterol Ratio and Insulin Resistance in Individuals With Obesity: Cross-Sectional Study of Chinese and U.S. Cohorts [0.03%]
基于中国和美国队列的肥胖人群的中性粒细胞与高密度脂蛋白胆固醇比值与胰岛素抵抗的相关性横断面研究
Zhenguang Mo,Yuzhou Yang,Zhenpeng Wu et al.
Zhenguang Mo et al.
This study aimed to evaluate whether the neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) is independently associated with Insulin Resistance (IR) among individuals with obesity and to examine the robustness of this associatio...
Triacylglycerol-Based Insulin Resistance Indices and Post-Transplantation Diabetes Mellitus After Liver Transplantation [0.03%]
基于三酰甘油的胰岛素抵抗指标与肝移植后糖尿病 mellitus
Mateo Chvatal-Medina,Yakun Li,Adrian Post et al.
Mateo Chvatal-Medina et al.
Background: Post-transplant diabetes mellitus (PTDM) is a common complication following liver transplant (LT) and is associated with adverse outcomes. The triacylglycerol-glucose product (TyG) and the triacylglycerol-to-h...
Association of DNA Methylation-Derived C-Reactive Protein Predictors With All-Cause Mortality and Blood Lipids in Adults Aged ≥ 50 Years in the United States [0.03%]
基于DNA甲基化推导的C-反应蛋白预测因素与美国≥50岁成年人全因死亡率和血液脂质的关系
Yu Yan,Zhipeng Gong,Shuangliang Ma
Yu Yan
Chronic low-grade inflammation contributes to aging, metabolic dysfunction, and age-related diseases. High-sensitivity C-reactive protein (HsCRP) is widely used but limited by short-term variability. DNA methylation-based CRPMort derived fr...