Leonard M Freeman,M Donald Blaufox
Leonard M Freeman
Physiology and pathophysiology of incidental findings detected on FDG-PET scintigraphy [0.03%]
氟脱氧葡萄糖正电子发射断层扫描的偶然发现的生理和病理生理学
Yiyan Liu,Nasrin V Ghesani,Lionel S Zuckier
Yiyan Liu
A routine feature of positron emission tomography/computed tomography (PET/CT) imaging is whole-body acquisition that results in many unexpected findings identified outside of the primary region of abnormality. Furthermore, (18)F-fluorodeox...
Altered biodistribution on FDG-PET with emphasis on brown fat and insulin effect [0.03%]
FDG-PET影像异常摄取的分布：关于棕色脂肪组织及胰岛素的影响
Christian Cohade
Christian Cohade
(18)F-fluorodeoxyglucose (FDG) is the radiotracer used in the vast majority of positron emission tomography (PET) cancer studies. FDG is a powerful radiotracer that provides valuable data in many cancer types. Normal FDG biodistribution is ...
Altered biodistribution and incidental findings on gallium and labeled leukocyte/bone marrow scans [0.03%]
镓和标记白细胞/骨髓扫描的生物分布改变及偶然发现
Charito Love,Christopher J Palestro
Charito Love
Gallium-67 citrate and labeled leukocyte imaging are established procedures for diagnosing inflammation and infection. Knowledge of the normal biodistribution of these tracers, variations, and unusual disease presentations improves the accu...
Altered biodistribution and incidental findings on myocardial perfusion imaging [0.03%]
心肌灌注显像的生物分布改变及偶然发现
Murthy Chamarthy,Mark I Travin
Murthy Chamarthy
Myocardial perfusion studies routinely are performed to evaluate for the presence and extent of coronary artery disease. The findings have prognostic and therapeutic implications. Routine display of the raw projection images allows visualiz...
Lionel S Zuckier,Leonard M Freeman
Lionel S Zuckier
Uptake in nonosseous, nonurologic tissues is occasionally found in the performance of bone scintigraphy. Proper interpretation of these cases depends on identifying the involved organs and appreciating the significance of the uptake. Becaus...
Altered biodistribution of radiopharmaceuticals: role of radiochemical/pharmaceutical purity, physiological, and pharmacologic factors [0.03%]
放射性药物生物分布改变：放射化学/药用纯度、生理和药理因素的作用
Shankar Vallabhajosula,Ronan P Killeen,Joseph R Osborne
Shankar Vallabhajosula
One of the most common problems associated with radiopharmaceuticals is an unanticipated or altered biodistribution, which can have a significant clinical impact on safety, scan interpretation, and diagnostic imaging accuracy. In their most...
Letter from the editors [0.03%]
编者来信
Leonard M Freeman,M Donald Blaufox
Leonard M Freeman
Preclinical and clinical studies of peptide receptor radionuclide therapy [0.03%]
肽受体放射性核素治疗的临床前和临床研究
Stefan E Pool,Eric P Krenning,Gerben A Koning et al.
Stefan E Pool et al.
In the 1980s, the (111)In-labeled somatostatin analog OctreoScan (Covidien, Hazelwood, MO) was developed for imaging of somatostatin receptor subtype 2 (sst(2)) overexpressing tumors. On the basis of this success, peptide receptor radionucl...
Ekaterina Dadachova
Ekaterina Dadachova
Actively targeted alpha-particles offer specific tumor cell killing action with less collateral damage to surrounding normal tissues than beta-emitters. During the last decade, radiolabeled peptides that bind to different receptors on the t...