The vitamin D receptor: new paradigms for the regulation of gene expression by 1,25-dihydroxyvitamin D(3) [0.03%]
维生素D受体：对1,25-二羟基维生素D3调节基因表达的新概念
J Wesley Pike,Mark B Meyer
J Wesley Pike
The actions of the vitamin D hormone 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) are mediated by the vitamin D receptor (VDR), a ligand-activated transcription factor that functions to control gene expression. After ligand activation, the ...
Vitamin D: metabolism [0.03%]
维生素D：代谢
Sylvia Christakos,Dare V Ajibade,Puneet Dhawan et al.
Sylvia Christakos et al.
The biologically active metabolite of vitamin D, 1,25(OH)(2)D(3), affects mineral homeostasis and has numerous other diverse physiologic functions including effects on growth of cancer cells and protection against certain immune disorders. ...
Sol Epstein
Sol Epstein
Derek Leroith
Derek Leroith
The human genome and sport, including epigenetics, gene doping, and athleticogenomics [0.03%]
人类基因组与体育运动（包括表观遗传学、基因兴奋剂和运动基因组学）
N C Craig Sharp
N C Craig Sharp
Hugh Montgomery's discovery of the first of more than 239 fitness genes together with rapid advances in human gene therapy have created a prospect of using genes, genetic elements, and cells that have the capacity to enhance athletic perfor...
Martin Flueck,Wouter Eilers
Martin Flueck
Endurance athletes demonstrate an exceptional resistance to fatigue when exercising at high intensity. Much research has been devoted to the contribution of aerobic capacity for the economy of endurance performance. Important aspects of the...
Geoffrey Goldspink,Barbara Wessner,Harald Tschan et al.
Geoffrey Goldspink et al.
This article discusses the inevitable use of growth factors for enhancing muscle strength and athletic performance. Much effort has been expended on developing a treatment of muscle wasting associated with a range of diseases and aging. Fra...
Anorexia, bulimia, and the female athlete triad: evaluation and management [0.03%]
厌食症、暴食症及女性运动员三联征的评价和处理
Felicia A Mendelsohn,Michelle P Warren
Felicia A Mendelsohn
The female athlete triad is an increasingly prevalent condition involving disordered eating, amenorrhea, and osteoporosis. An athlete can suffer from all 3 components of the triad, or just 1 or 2 of the individual conditions. The main eleme...
Procedures for monitoring recombinant erythropoietin and analogs in doping [0.03%]
重组促红细胞生成素和类似物的兴奋剂检测方法
Séverine Lamon,Neil Robinson,Martial Saugy
Séverine Lamon
Hemoglobin concentration is one of the principal factors of aerobic power and, consequently, of performance in many types of physical activities. The use of recombinant human erythropoietin is, therefore, particularly powerful for improving...
Dehydroepiandrosterone to enhance physical performance: myth and reality [0.03%]
脱氢表雄酮对提高体能的作用：神话与现实
Stefanie Hahner,Bruno Allolio
Stefanie Hahner
Dehydroepiandrosterone (DHEA) is secreted by the zona reticularis of the adrenal cortex and is converted into potent sex steroids in peripheral target cells. As oral DHEA administration can lead to dose-dependent increases in circulating an...