Derek LeRoith
Derek LeRoith
John Lyons rd,Catherine T Anthony,Eugene A Woltering
John Lyons rd
The first studies to assess in vitro angiogenesis in neuroendocrine tumors used animal-based assays to study the antiangiogenic properties of somatostatin analogs. Current technologies enable investigators to directly appraise the in vitro ...
Vay Liang W Go,Priya Srihari,Leigh Anne Kamerman Burns
Vay Liang W Go
Gastroenteropancreatic (GEP) neuroendocrine tumors (NETs) are relatively rare neoplasms that characteristically synthesize and secrete an excess of a variety of regulatory peptides, hormones, and neuroamines, which regulate gut and pancreat...
Novel anticancer agents in clinical trials for well-differentiated neuroendocrine tumors [0.03%]
用于分化良好神经内分泌肿瘤的临床试验新抗肿瘤药物
Sandrine Faivre,Marie-Paule Sablin,Chantal Dreyer et al.
Sandrine Faivre et al.
Neuroendocrine tumors (NETs) are rare malignancies that arise from endocrine cells located in various anatomic locations, with a dramatic increase in incidence during the last 30 years. Limited therapeutic options are currently available fo...
Barbara Zarebczan,Herbert Chen
Barbara Zarebczan
Although neuroendocrine tumors are rare, the more common types such as gastrointestinal and pancreatic carcinoids, medullary thyroid cancers, and small cell lung cancers have been studied in detail during the last few years. Data published ...
Glucagonlike peptide-1 receptor: an example of translational research in insulinomas: a review [0.03%]
GLP-1受体：胰岛素瘤转化研究的一个例子：综述
Emanuel Christ,Damian Wild,Jean Claude Reubi
Emanuel Christ
Glucagonlike peptide-1 receptors (GLP-1R) play an increasingly important role in endocrine gastrointestinal tumor management. In particular, virtually all benign insulinomas express GLP-1R in high density. Exendin-4 is a GLP-1 analog that h...
Circulating biomarkers in neuroendocrine tumors of the enteropancreatic tract: application to diagnosis, monitoring disease, and as prognostic indicators [0.03%]
肠胰神经内分泌肿瘤的循环生物标志物：在诊断、监测疾病和预后指标中的应用
Joy E S Ardill,Thomas M O&#x;Dorisio
Joy E S Ardill
Neuroendocrine tumors (NETs) are difficult to diagnose. Their symptoms may be vague or intermittent, and are frequently associated with much more common diseases; many of the tumors may be asymptomatic. Therefore, diagnosis can be delayed f...
David A Taylor-Fishwick,Gary L Pittenger
David A Taylor-Fishwick
Building on the elaborate research studies that have helped map out key decision points in the process of pancreas development, reprogramming of pluripotent embryonic stem cells or induced pluripotent stem cells offers the possibility of ov...
Jessica Chang,Christopher K Rayner,Karen L Jones et al.
Jessica Chang et al.
Diabetes is the most common cause of gastroparesis and it is now recognized that the relationship between gastric emptying and glycemia is complex and intertwined. Postprandial blood glucose levels influence, and are influenced by, the rate...
Katherine A Simpson,Stephen R Bloom
Katherine A Simpson
Precise automatic control of food intake and energy expenditure maintains a steady weight and is fundamental to survival. The brainstem and hypothalamus are key areas within the brain that integrate peripheral signals from the gut and adipo...