Thyroid and Aging [0.03%]
甲状腺与衰老
Jennifer S R Mammen
Jennifer S R Mammen
Older adults are more vulnerable to the negative effects of excess thyroid hormone and may even be protected by lower levels of thyroid hormone. The diagnosis and management of thyroid disease in older adults needs to account for aging-rela...
Male Reproduction and Aging [0.03%]
男性生育与衰老
Maria Gabriela Figueiredo,Thiago Gagliano-Jucá,Shehzad Basaria
Maria Gabriela Figueiredo
Recent publications of well-conducted population studies have informed us that the syndromic prevalence of age-related low testosterone, also known as late-onset hypogonadism, is quite low. Several well-conducted trials in middle-aged and o...
Catherine Kim,Melissa Wellons
Catherine Kim
Natural menopause is defined as the cessation of menstruation among women who have not undergone hysterectomy or bilateral oophorectomy. The implications of menopause management are particularly important with the aging of the population an...
Betul A Hatipoglu
Betul A Hatipoglu
Diabetes Remission [0.03%]
糖尿病缓解
Adriana G Ioachimescu
Adriana G Ioachimescu
Samantha Paul,Christian Kim,Mohamed Kamel Soliman et al.
Samantha Paul et al.
The prevalence of diabetic retinopathy is steadily increasing as the population of patients with diabetes grows. In the past decade, the development of anti-VEGF agents has dramatically changed the treatment landscape for diabetic retinopat...
Remission with an Intervention: Is Metabolic Surgery the Ultimate Solution? [0.03%]
干预下的缓解：代谢手术是最终解决方案吗？
Zubaidah Nor Hanipah,Francesco Rubino,Philip R Schauer
Zubaidah Nor Hanipah
Long-term remission of type 2 diabetes following lifestyle intervention or pharmacotherapy, even in patients with mild disease, is rare. Long-term remission following metabolic surgery however, is common and occurs in 23% to 98% depending o...
Physiology Reconfigured: How Does Bariatric Surgery Lead to Diabetes Remission? [0.03%]
生理重塑：代谢手术何以逆转糖尿病？
Vance L Albaugh,Christopher Axelrod,Kathryn P Belmont et al.
Vance L Albaugh et al.
Bariatric surgery improves glucose homeostasis and glycemic control in patients with type 2 diabetes. Over the past 20 years, a breadth of studies has been conducted in humans and rodents aimed to identify the regulatory nodes responsible f...
Intervention with Therapeutic Agents, Understanding the Path to Remission to Type 2 Diabetes: Part 2 [0.03%]
药物干预，理解2型糖尿病缓解的路径：第二部分
Shuai Hao,Guillermo E Umpierrez,Priyathama Vellanki
Shuai Hao
Type 2 diabetes is characterized by progressive decline in pancreatic β-cell function. Newer agents, such as glucagon-like peptide-1 receptor agonist (GLP-1RA) and dual incretin agonists, can augment β-cell function and delay the need for...
Intervention with Therapeutic Agents, Understanding the Path to Remission in Type 2 Diabetes: Part 1 [0.03%]
治疗药物干预，2型糖尿病缓解路径探索（上篇）
Shuai Hao,Guillermo E Umpierrez,Tanicia Daley et al.
Shuai Hao et al.
Type 2 diabetes is characterized by progressive decline in pancreatic β-cell function. Studies in adult subjects with newly diagnosed type 2 diabetes have reported that intensive insulin therapy followed by various antihyperglycemic medica...