Sayali A Ranadive,Stephen M Rosenthal
Sayali A Ranadive
Fluid homeostasis requires adequate water intake, regulated by an intact thirst mechanism and appropriate free water excretion by the kidneys, mediated by appropriate secretion of arginine vasopressin (AVP, also known as antidiuretic hormon...
Robert Rapaport
Robert Rapaport
Derek LeRoith
Derek LeRoith
Recombinant human insulin-like growth factor-1 treatment: ready for primetime [0.03%]
重组人生长激素类似物IGF-1的治疗：准备就绪
George M Bright,Jessica R Mendoza,Ron G Rosenfeld
George M Bright
The combination of targeted gene knockout studies in animals and human mutational analysis has demonstrated the key role of the IGF system in mammalian growth, both in utero and postnatally. The concept of IGF deficiency as a diagnostic cat...
Strategies for maximizing growth in puberty in children with short stature [0.03%]
儿童身材矮小/pubertal期促进生长的策略
Nelly Mauras
Nelly Mauras
The approach to the child with growth retardation who is in puberty remains an important clinical challenge. The use of high-dose growth hormone (GH), suppression of puberty with GnRH analogs in combination with GH, and the use of selective...
Sherry L Franklin,Mitchell E Geffner
Sherry L Franklin
Growth hormone is a widely used hormone. This article describes its historical use, current indications and studies for possible future uses.
Galia Gat-Yablonski,Michal Yackobovitch-Gavan,Moshe Phillip
Galia Gat-Yablonski
Children's growth is a hallmark of their normal development and the association between nutrition and linear growth in children is well accepted. Growth requires an adequate supply of many different nutritional factors, some form the "build...
Metabolic syndrome in pediatrics: old concepts revised, new concepts discussed [0.03%]
儿科代谢综合征：重新审视旧概念，讨论新概念
Ebe D&#x;Adamo,Nicola Santoro,Sonia Caprio
Ebe D&#x;Adamo
The worldwide epidemic of childhood obesity in the last decades is responsible for the occurrence in pediatrics of disorders once mainly found in adults, such as the metabolic syndrome. A key factor in the pathogenesis of metabolic syndrome...
Melissa K Crocker,Jack A Yanovski
Melissa K Crocker
This article reviews factors that contribute to excessive weight gain in children and outlines current knowledge regarding approaches for treating pediatric obesity. Most of the known genetic causes of obesity primarily increase energy inta...
Perinatal endocrinology: common endocrine disorders in the sick and premature newborn [0.03%]
围生期内分泌学：危重新生儿和早产儿的常见内分泌疾病
Sharon J Hyman,Yeray Novoa,Ian Holzman
Sharon J Hyman
Endocrine disorders are common in infants in the neonatal ICU. They often are associated with prematurity, low birth weight or very low birth weight, and small size for gestational age. They also frequently occur in infants who are critical...