Christopher Chase,Radhey S Kaushik
Christopher Chase
This article discusses key concepts important for mucosal immunity. The mucosa is the largest immune organ of the body. The mucosal barrier (the tight junctions and the "kill zone") along with the mucosa epithelial cells maintaining an anti...
Genetic and Epigenetic Regulation of Immune Response and Resistance to Infectious Diseases in Domestic Ruminants [0.03%]
家养反刍动物免疫反应及抵抗传染性疾病发生的遗传和表观遗传调控研究进展
Mehdi Emam,Alexandra Livernois,Marlene Paibomesai et al.
Mehdi Emam et al.
Infectious diseases are the outcome of complex interactions between the host, pathogen, and environment. After exposure to a pathogen, the host immune system uses various mechanisms to remove the pathogen. However, environmental factors and...
Alan J Young
Alan J Young
Vaccination is a critical tool in modern animal production and key to maintaining animal health. Adjuvants affect the immune response by increasing the rate, quantity, or quality of the protective response generated by the target antigens. ...
Rick N Funston,J Travis Mulliniks
Rick N Funston
Devin Broadhead,J Travis Mulliniks,Rick N Funston
Devin Broadhead
Beef production is a complex system, in which cows are expected to perform in varied environmental conditions. In cattle, the most commonly reported developmental programming influence is nutrient restriction during the prenatal period due ...
Adam F Summers,Eric J Scholljegerdes
Adam F Summers
Stimuli experienced in utero can have a lasting impact on livestock growth, reproduction, and performance. Variations in environment, production system, and management strategies lead to discrepancies in the literature regarding how specifi...
Multigenerational Effects [0.03%]
跨世代效应
Andrew J Roberts,El Hamidi Hay
Andrew J Roberts
Environmental influences resulting in epigenetic mediation of gene expression can affect multiple generations via direct effect (first generation); direct or maternally mediated effects on the fetus (second generation), or gonadal cell line...
In Utero Heat Stress Programs Reduced Performance and Health in Calves [0.03%]
母体热应激影响犊牛生长性能和健康编程效应的研究进展
Geoffrey E Dahl,Amy L Skibiel,Jimena Laporta
Geoffrey E Dahl
Heat stress during late gestation adversely impacts the developing calf. Calves that experience heat stress are born at a lower bodyweight and those deficits persist at least until puberty. In utero heat stress reduces passive transfer and ...
Reinaldo F Cooke
Reinaldo F Cooke
The concept of developmental programming was established using epidemiologic studies that investigated chronic illnesses in humans, such as coronary heart disease and hypertension. In livestock species, the impacts of developmental programm...
Robert A Cushman,George A Perry
Robert A Cushman
Developmental programming became an area of interest to understand negative environmental impacts on progeny performance. Recently, the concept that we may be able to harness developmental programming to target animals to their niche in the...