A generalized dSpliceType framework to detect differential splicing and differential expression events using RNA-Seq [0.03%]
一个使用RNA序检测差异拼接和差异表达事件的广义dSpliceType框架
Dongxiao Zhu,Nan Deng,Changxin Bai
Dongxiao Zhu
Transcriptomes are routinely compared in term of a list of differentially expressed genes followed by functional enrichment analysis. Due to the technology limitations of microarray, the molecular mechanisms of differential expression is po...
A computational method for prediction of saliva-secretory proteins and its application to identification of head and neck cancer biomarkers for salivary diagnosis [0.03%]
一种预测唾液分泌蛋白的计算方法及其在寻找头颈部癌症生物标志物中的应用以实现唾液诊断
Ying Sun,Wei Du,Chunguang Zhou et al.
Ying Sun et al.
Human saliva is rich in proteins, which have been used for disease detection such as oral diseases and systematic diseases. In this paper, we present a computational method for predicting secretory proteins in human saliva based on two sets...
A Touch-Communication Framework for Drug Delivery Based on a Transient Microbot System [0.03%]
一种基于瞬态微机器人系统的药物递送触觉通信框架
Yifan Chen,Panagiotis Kosmas,Putri Santi Anwar et al.
Yifan Chen et al.
Recent progress in bioresorbable radio frequency electronics and engineered bacteria has promised the prospect of realizing a transient microbot (TM) system for therapeutic applications. The inorganic or organic miniature robots will dissol...
Network output controllability-based method for drug target identification [0.03%]
基于网络输出可控性的药物靶点识别方法
Lin Wu,Yichao Shen,Min Li et al.
Lin Wu et al.
Biomolecules do not perform their functions alone, but interactively with one another to form so called biomolecular networks. It is well known that a complex disease stems from the malfunctions of corresponding biomolecular networks. There...
Motility of actin filaments on micro-contact printed myosin patterns [0.03%]
微接触印刷肌球蛋白图案上肌动蛋白(filament)的运动性研究
J Hajne,K L Hanson,H van Zalinge et al.
J Hajne et al.
Protein molecular motors, which convert, directly and efficiently, chemical energy into motion, are excellent candidates for integration in hybrid dynamic nanodevices. To integrate and use the full potential of molecular motors in these dev...
Identifying Intracellular pDNA Losses From a Model of Nonviral Gene Delivery [0.03%]
非病毒基因传递模型的细胞内pDNA损失识别方法
Timothy Michael Martin,Beata Joanna Wysocki,Tadeusz Antoni Wysocki et al.
Timothy Michael Martin et al.
Nonviral gene delivery systems are a type of nanocommunication system that transmit plasmid packets (i.e., pDNA packets) that are programmed at the nanoscale to biological systems at the microscopic cellular level. This engineered nanocommu...
Nematic colloidal swarms assembled and transported on photosensitive surfaces [0.03%]
在光敏表面上组装和运输向列型胶体群集
Sergi Hernàndez-Navarro,Pietro Tierno,Jordi Ignés-Mullol et al.
Sergi Hernàndez-Navarro et al.
We demonstrate a novel method to assemble and transport swarms of colloidal particles by combining liquid crystal enabled electrophoresis and photo-sensitive surface patterning. Colloidal particles are propelled in a nematic liquid crystal ...
Xiao-Bo Li,Forbes Burkowski
Xiao-Bo Li
Elastic network interpolation (ENI) is an efficient method for generating intermediate conformations between two end protein conformations. Its current formulation uses interatomic distance. We show how this can be generalized to interatomi...
Detecting SNP combinations discriminating human populations from HapMap data [0.03%]
基于Hapmap数据鉴定区分人类群体的SNP组合
XiaoJun Ding,Min Li,HaiHua Gu et al.
XiaoJun Ding et al.
The genomes of different human beings are similar. There are only a relatively small number of genetic differences between people. The genetic differences between people are very worthy of study. Researchers have proposed the fixation index...
Heterogeneous network model to infer human disease-long intergenic non-coding RNA associations [0.03%]
一种用于推断人类疾病与长非编码RNA关联的异网模型
Gamage Upeksha Ganegoda,Min Li,Weiping Wang et al.
Gamage Upeksha Ganegoda et al.
With the knowledge of molecular biology it is highlighting that long non-coding RNAs (lncRNAs) play a critical role in many important biological processes, such as imprinting control, cell differentiation, immune responses, human diseases, ...