Michael A Spinner,Ranjana H Advani
Michael A Spinner
Hodgkin lymphoma is the most common hematologic malignancy diagnosed during pregnancy, attributed to overlapping peak incidence with the reproductive years. Management during pregnancy requires a multidisciplinary team including hematology/...
Hanan Alharthy,Sairah Ahmed
Hanan Alharthy
Stem cell transplantation remains a cornerstone in managing relapsed/refractory classic Hodgkin lymphoma, though its role is evolving with the integration of targeted therapies. Autologous stem cell transplantation achieves cure rates of 50...
New Standards in Advanced-stage Hodgkin Lymphoma: Selecting a Novel Regimen [0.03%]
经典复发难治霍奇金淋巴瘤的治疗进展及选择
Hunter Cassidy Cochran,Nancy L Bartlett
Hunter Cassidy Cochran
The management of advanced-stage Hodgkin lymphoma has entered an era defined by immune-based therapy. Nivolumab-AVD has become the preferred frontline regimen, delivering high cure rates with minimal toxicity across age groups. BrECADD rema...
Circulating Tumor DNA Assessment in Classic Hodgkin Lymphoma: Ready for Primetime? [0.03%]
经典霍奇金淋巴瘤的循环肿瘤DNA检测：准备就绪了吗？
Tanja Zamrik,Bastian von Tresckow,Stefan K Alig
Tanja Zamrik
Circulating tumor DNA (ctDNA) has emerged as a promising biomarker in classic Hodgkin lymphoma (cHL). Abundant ctDNA shedding from Hodgkin/Reed-Sternberg cells enables comprehensive molecular profiling directly from plasma. Recent studies h...
Selection of a Salvage Regimen for Relapsed or Refractory Classic Hodgkin Lymphoma in the Era of Novel Therapies [0.03%]
新型疗法时代复发/难治性经典型霍奇金淋巴瘤挽救方案的选择
Annie Xiao,Matthew Mei
Annie Xiao
The treatment landscape of classical Hodgkin lymphoma continues to evolve with earlier use of novel agents. Most recently, the addition of PD-1 inhibitors into frontline therapy has improved cure rates but introduced new challenges at relap...
Matthew C Perez,Jonathan S Zager
Matthew C Perez
Approximately 10% of patients with melanoma develop in-transit disease (ITM). Although resection may be performed in patients with limited, fully resectable disease, many patients with ITM present with bulky, unresectable disease, which can...
Kristen E Limbach,Darrell Fan,Laleh G Melstrom
Kristen E Limbach
Remote monitoring and telehealth platforms have been of increasing interest since the beginning of the Corona Virus disease-2019 pandemic, with rising rates of implementation. Surgical oncology patients are a unique population that may deri...
Tommaso Pollini,Paul Wong,Ajay V Maker
Tommaso Pollini
Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are a common entity with a prevalence in the general population that increases with age. Depending on the involvement of the main pancreatic duct, they can be divided into mai...
Shannon K Swisher,Keith A Delman
Shannon K Swisher
Standard use of adjuvant immunotherapy has significantly improved clinical outcomes in melanoma. Neoadjuvant immunotherapy has further enhanced these benefits in the setting of advanced disease. Lack of a reliable biomarker to monitor treat...
Lauren M Janczewski,Jeffrey D Wayne
Lauren M Janczewski
Dermatofibrosarcoma protuberans is a rare, low-grade sarcoma characterized by lateral tentacle-like extensions into the surrounding subcutaneous tissue. Although surgical resection remains that mainstay of treatment, achieving negative marg...