Daniel Szvarca,Kunal Jajoo
Daniel Szvarca
Biliary tract neoplasms comprise a heterogeneous group of malignancies associated with diagnostic complexity, and high morbidity and mortality. Hence, timely diagnosis, accurate staging, and effective therapeutic modalities are crucial to p...
Molecularly Guided Therapy in Hepatobiliary Cancers: Current Standards and Emerging Horizons [0.03%]
分子指导的肝胆道癌症治疗：现行标准与未来前景
Jorge Adeva,Valerie S Kalluri,Fen Saj et al.
Jorge Adeva et al.
Hepatobiliary malignancies constitute a major global oncologic burden, encompassing a heterogeneous spectrum of tumors comprised of hepatocellular carcinoma (HCC) and biliary tract cancers (BTC). While precision oncology has transformed BTC...
Lily V Saadat,William R Jarnagin
Lily V Saadat
Biliary tract malignancies, including perihilar and distal cholangiocarcinoma and gallbladder cancer, are anatomically complex tumors for which resection remains the only curative treatment. Optimal management requires multidisciplinary eva...
Advances in Pediatric Oncology: Enhancements in Risk Stratification, Targeted Therapeutics, and Cancer Survivorship Care [0.03%]
儿科肿瘤学进展：危险因素分层、靶向治疗和癌症幸存者护理的改善
Sara Zarnegar-Lumley
Sara Zarnegar-Lumley
Kirk D Wyatt,Samuel L Volchenboum
Kirk D Wyatt
Proposed uses of "big data" in pediatric oncology are growing alongside the notoriety that big data has achieved from uses outside of medicine. While big data approaches hold promise to revolutionize how we collect, analyze, and act upon bi...
Subsequent Malignant Neoplasms in Childhood Cancer Survivors: Identifying Risks and Screening Recommendations [0.03%]
儿童癌症幸存者继发恶性肿瘤的风险评估及筛查建议
Kerri Becktell,Kelly Cotchett,Rebecca Volmy et al.
Kerri Becktell et al.
A subsequent malignant neoplasm (SMN) is defined as a distinctly new histologic malignant neoplasm that occurs after completion of treatment of a primary malignancy or hematopoietic stem cell transplant. The risk for SMNs in survivors is es...
Neurocognitive Late Effects Among Childhood Cancer Survivors: A Holistic Review of Clinical Risk Factors [0.03%]
儿童癌症幸存者的神经认知晚期效应：临床危险因素的全面回顾
Rachel S Werk,Katharine Rae Lange
Rachel S Werk
Childhood cancer survivors are at risk for neurocognitive deficits because of the past treatment received and, if involving the central nervous system, the malignancy itself. It is vital to maintain a holistic perspective in caring for chil...
Oncofertility in Pediatric and Adolescent Patients: Current Practice and Future Directions [0.03%]
儿科和青少年肿瘤生殖医学的现状与未来方向
Rohini Chakravarthy,Monica M Laronda,Sara Zarnegar-Lumley
Rohini Chakravarthy
Childhood cancer survivors cite reproductive health and future fertility as important to their quality of life in survivorship. The discipline of oncofertility has made significant progress in recent decades. With the development of risk st...
William F Hartsell,Alexander A Harris,Stephan A Mihalcik et al.
William F Hartsell et al.
Radiation therapy is an integral part of treatment of many pediatric cancers, but is associated with long-term side effects. Recent advances in radiation therapy, and in particular in the use of particle therapy with protons, have allowed t...
Advances in Pediatric Hodgkin Lymphoma with an Eye on Disparities and Vulnerable Populations [0.03%]
儿童霍奇金淋巴瘤研究进展及对不平等和弱势人群的关注
Jennifer A Belsky,Jamie Shoag,Paul D Harker-Murray et al.
Jennifer A Belsky et al.
Advances in pediatric and adolescent young adult Hodgkin lymphoma (HL), including the incorporation of targeted therapy and immunotherapy have resulted in excellent cure rates with survival greater than 90%, including patients with advanced...