Selection of a Salvage Regimen for Relapsed or Refractory Classic Hodgkin Lymphoma in the Era of Novel Therapies [0.03%]
新型疗法时代复发/难治性经典型霍奇金淋巴瘤挽救方案的选择
Annie Xiao,Matthew Mei
Annie Xiao
The treatment landscape of classical Hodgkin lymphoma continues to evolve with earlier use of novel agents. Most recently, the addition of PD-1 inhibitors into frontline therapy has improved cure rates but introduced new challenges at relap...
Matthew C Perez,Jonathan S Zager
Matthew C Perez
Approximately 10% of patients with melanoma develop in-transit disease (ITM). Although resection may be performed in patients with limited, fully resectable disease, many patients with ITM present with bulky, unresectable disease, which can...
Kristen E Limbach,Darrell Fan,Laleh G Melstrom
Kristen E Limbach
Remote monitoring and telehealth platforms have been of increasing interest since the beginning of the Corona Virus disease-2019 pandemic, with rising rates of implementation. Surgical oncology patients are a unique population that may deri...
Tommaso Pollini,Paul Wong,Ajay V Maker
Tommaso Pollini
Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas are a common entity with a prevalence in the general population that increases with age. Depending on the involvement of the main pancreatic duct, they can be divided into mai...
Shannon K Swisher,Keith A Delman
Shannon K Swisher
Standard use of adjuvant immunotherapy has significantly improved clinical outcomes in melanoma. Neoadjuvant immunotherapy has further enhanced these benefits in the setting of advanced disease. Lack of a reliable biomarker to monitor treat...
Lauren M Janczewski,Jeffrey D Wayne
Lauren M Janczewski
Dermatofibrosarcoma protuberans is a rare, low-grade sarcoma characterized by lateral tentacle-like extensions into the surrounding subcutaneous tissue. Although surgical resection remains that mainstay of treatment, achieving negative marg...
Alexa J Hughes,Alexandria D McDow,Hadley E Ritter et al.
Alexa J Hughes et al.
Adrenocortical carcinoma is a rare, aggressive cancer with a poor prognosis. Management of early-stage disease relies on surgical resection, which remains the only potentially curative therapy. Open surgery remains the standard of care, wit...
Rachel Hae-Soo Joung,Jeffrey D Wayne
Rachel Hae-Soo Joung
Retroperitoneal sarcoma is composed of a heterogeneous group of mesenchymal neoplasms that has poor prognosis. Although surgery remains the mainstay of treatment, achieving complete surgical resection with adequate margins is challenging, g...
Hepatic Artery Infusion Pump Therapy in Unresectable and Resectable Liver Tumors [0.03%]
不可手术和可手术肝肿瘤的肝动脉灌注泵治疗
Lauren M Janczewski,Ryan P Merkow
Lauren M Janczewski
Hepatic artery infusion (HAI) chemotherapy is a regional, intra-arterial treatment of hepatic malignancies, delivering high-dose floxuridine directly to the liver. The rationale for HAI is based on the dominant blood supply of liver tumors ...
Neoadjuvant Chemotherapy for Nonmetastatic Breast Cancer: How Response Impacts Locoregional and Adjuvant Systemic Therapy Decision Making [0.03%]
新辅助化疗在非转移性乳腺癌中的应用:如何根据疗效反应决定局部区域和术后全身治疗方案的选择
Giacomo Montagna,Emanuela Ferraro,Melissa L Pilewskie
Giacomo Montagna
Neoadjuvant chemotherapy is now considered standard of care for most of the patients with clinically node-positive disease, and for a large proportion of triple-negative breast cancer and HER2-positive tumors. Here we reviewed the benefit o...