Debate: Improvements in Systemic Therapies for Liver Metastases Will Increase the Role of Locoregional Treatments [0.03%]
debate:系统性疗法在肝转移治疗中的改善将会增加局部治疗的作用
Yoshikuni Kawaguchi,Mario De Bellis,Elena Panettieri et al.
Yoshikuni Kawaguchi et al.
The benefit of resection of liver metastases depends on primary diseases. Neuroendocrine tumors are associated with favorable prognosis after resection of liver metastases. Gastric cancer has worse tumor biology, and resection of gastric li...
Systemic Therapy Improvements Will Render Locoregional Treatments Obsolete for Patients with Cancer with Liver Metastases [0.03%]
系统疗法的改善将使得肝转移癌患者的局部区域治疗过时
Satya Das,Jordan Berlin
Satya Das
Hepatic metastases are a major cause of morbidity and mortality for patients with cancer. Apart from curative resection, which offers patients the potential for long-term survival, an array of locoregional therapies, with limited evidence o...
Hepatic Perfusion for Diffuse Metastatic Cancer to the Liver: Open and Percutaneous Techniques [0.03%]
肝转移癌的肝灌注治疗：开放手术与经皮技术
H Richard Alexander Jr,Virginia Devi-Chou
H Richard Alexander Jr
The management of patients with diffuse liver metastases remains a significant clinical challenge. In many cancer patients, metastatic disease may be isolated to the liver or the liver may be the dominant site of progressive metastatic canc...
Paul B Romesser,Brian P Neal,Christopher H Crane
Paul B Romesser
Stereotactic ablative radiotherapy (SABR) commonly is used for small liver metastases. Modern conformal radiotherapy techniques, including 3-dimensional conformal radiotherapy and intensity-modulated radiation therapy, enable the safe deliv...
Louise C Connell,Nancy E Kemeny
Louise C Connell
Colorectal cancer (CRC) is one of the leading cancers globally in terms of both incidence and cancer-related mortality. Liver metastatic disease is the main prognostic driver for patients with CRC. The management options for liver metastati...
Is There a Role for Locoregional Therapies for Non-colorectal Gastrointestinal Malignancies? [0.03%]
局部治疗在非结直肠胃肠恶性肿瘤中的作用是什么？
Gilton Marques Fonseca,Maria Ignez Freitas Melro Braghiroli,Jaime Arthur Pirola Kruger et al.
Gilton Marques Fonseca et al.
The liver is the most common site of metastases from solid gastrointestinal tract tumors. Over the past few decades, the role of locoregional therapies, resection and thermal ablation, for neuroendocrine and colorectal liver metastases has ...
Diederik J Höppener,Dirk J Grünhagen,Alexander M M Eggermont et al.
Diederik J Höppener et al.
An overview of all liver-directed locoregional therapies, including surgical resection for melanoma liver metastases (MLMs), is provided. MLM patients are divided by their primary melanoma location; cutaneous, uvea (eye), and mucosal melano...
Chandrasekhar Padmanabhan,Daniel P Nussbaum,Michael D&#x;Angelica
Chandrasekhar Padmanabhan
Approximately 50% of colorectal cancer patients develop liver metastases. Hepatic metastases represent the most common cause of colorectal cancer-related mortality. Metastasectomy, if possible, represents the most effective treatment strate...
Kevin M Elias,Ross S Berkowitz,Neil S Horowitz
Kevin M Elias
Ultra high-risk gestational trophoblastic neoplasia (GTN) refers to patients with World Health Organization prognostic risk scores of at least 13. The mortality risk for these patients averages 30%. Ultra high-risk GTN more frequently prese...
Initial Diagnosis and Treatment of Low-Risk Gestational Trophoblastic Neoplasia [0.03%]
低危妊娠滋养细胞肿瘤的初始诊断与处理
Stephanie Alimena,Kevin M Elias,Neil S Horowitz et al.
Stephanie Alimena et al.
Gestational trophoblastic neoplasia (GTN) is a rare form of cancer that is treated according to the World Health Organization (WHO) risk score, which predicts responsiveness to single-agent chemotherapy. Patients with WHO risk scores ≤6 ha...