Michael Krathen
Michael Krathen
The detection of cutaneous melanoma still largely relies on clinical suspicion, skin biopsy, and histopathologic evaluation. New technologies are being evaluated to bypass the skin biopsy in the detection of melanoma. The quest for reliable...
Update and clinical use of imaging technologies for pigmented lesions of the skin [0.03%]
皮肤色素病变的影像技术更新及临床应用
Allison T O&#x;Donnell,Caroline C Kim
Allison T O&#x;Donnell
The incidence of melanoma is on the rise, and early detection of disease is imperative to reduce mortality. Dermatologists are key players in the early detection of melanoma; however, some clinicians rely on their clinical examination witho...
Wound healing update [0.03%]
伤口愈合的新进展
Laurel M Morton,Tania J Phillips
Laurel M Morton
The management of acute and chronic wounds has drastically changed within the past 20 years. This update focuses on the most recent recommendations for acute wound care as well as new technologies that are available for chronic wounds. ...
Brian Poligone,Peter Heald
Brian Poligone
In the management of patients with cutaneous T-cell lymphoma (CTCL), there are numerous distinct therapy options. Each of these therapies is discussed in terms of when to use it, what factors limit the success of the treatment, and what to ...
Advances in management of atopic dermatitis: new therapies and novel uses of existing treatments [0.03%]
特应性皮炎的治疗进展：新疗法及现有疗法的新应用
Elizabeth P Chase,April W Armstrong
Elizabeth P Chase
Atopic dermatitis (AD) is a chronic inflammatory skin condition marked by intensely pruritic, eczematous changes. First-line therapy includes topical corticosteroids during an exacerbation and long-term emollient use, followed by topical ca...
M Shane Chapman
M Shane Chapman
Vitamin A is required for the proper functioning of many important metabolic and physiologic activities, including vision, gene transcription, the immune system and skin cell differentiation. Both excessive and deficient levels of vitamin A...
Jennifer G Powers,Barbara A Gilchrest
Jennifer G Powers
"Vitamin D" is the term commonly used to denote the lipid-soluble hormone critical for calcium homeostasis and skeletal maintenance. A precursor to the active compound is found in many plants and animal tissues and can be absorbed from the ...
Brooke C Sikora
Brooke C Sikora
Elucidating the role of molecular signaling pathways in the tumorigenesis of basal cell carcinoma [0.03%]
阐明分子信号通路在基底细胞癌发生中的作用
Jean Y Tang
Jean Y Tang
The Hedgehog signaling pathway has been identified as fundamentally important to normal embryonic development in living organisms ranging from fruit flies to mammals. Postdevelopmentally, it remains active in hair and skin cells. Abnormal a...
Jean Y Tang,Ashfaq A Marghoob
Jean Y Tang
A number of therapies that target components of the Hedgehog signaling pathway currently are in clinical trials. The specific molecules that seem most promising in basal cell carcinoma and a number of other cancers are those that target the...