The itch of liver disease [0.03%]
肝病的痒感
Nora V Bergasa
Nora V Bergasa
Itch is a complication of liver disease. It is hypothesized that this type of itch is mediated, at least in part, by increased central opioidergic tone; a peripheral component may coexist. The role of serotonin, bile acids, substance P, and...
Neuropathic itch [0.03%]
神经性瘙痒症
Anne Louise Oaklander
Anne Louise Oaklander
Chronic itch can be caused by dysfunctions of itch-sensing neurons that produce sensory hallucinations of pruritogenic stimuli. The cellular and molecular mechanisms are still unknown. All neurological disease categories have been implicate...
Judith Hong,Joerg Buddenkotte,Timothy G Berger et al.
Judith Hong et al.
Atopic dermatitis is a common, pruritic, inflammatory skin disorder. Chronic, localized, or even generalized pruritus is the diagnostic hallmark of atopic dermatitis, and its management remains a challenge for physicians. The threshold for ...
Akihiko Ikoma,Ferda Cevikbas,Cordula Kempkes et al.
Akihiko Ikoma et al.
Itch has been described for many years as an unpleasant sensation that evokes the urgent desire to scratch. Studies of the neurobiology, neurophysiology, and cellular biology of itch have gradually been clarifying the mechanism of itch both...
Timothy G Berger,Martin Steinhoff
Timothy G Berger
The role of targeted molecular inhibitors in the management of advanced nonmelanoma skin cancer [0.03%]
靶向分子抑制剂在晚期非黑色素瘤皮肤癌治疗中的作用
Kevin W O&#x;Bryan,Desiree Ratner
Kevin W O&#x;Bryan
Surgical treatment remains the standard of care for nonmelanoma skin cancer and is successful for the vast majority of patients with these tumors. The treatment of patients with metastatic or unresectable nonmelanoma skin cancer, however, h...
Timothy S Wang,Patrick J Byrne,Lisa K Jacobs et al.
Timothy S Wang et al.
Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal cutaneous malignancy that is not usually suspected at the time of biopsy. Because of its increasing incidence and the discovery of a possible viral association, interest in ...
Current approaches to skin cancer management in organ transplant recipients [0.03%]
器官移植受者皮肤癌管理的现行方法
Meena K Singh,Jerry D Brewer
Meena K Singh
Approximately 225,000 people are living with organ transplants in the United States. Organ transplant recipients have a greater risk of developing skin cancer, including basal cell carcinoma, squamous cell carcinoma, and malignant melanoma,...
Nicole R LeBoeuf,Chrysalyne D Schmults
Nicole R LeBoeuf
Cutaneous squamous cell carcinoma (CSCC) is the second most common malignancy occurring in white patients in the United States and incidence rates are increasing. While the majority of the 87,000-760,000 cases that occur yearly in the U.S. ...
Lori Brightman,Melanie Warycha,Robert Anolik et al.
Lori Brightman et al.
Novel strategies are urgently needed to address the millions of nonmelanoma skin cancers treated in the United States annually. The need is greatest for those patients who are poor surgical candidates or those prone to numerous nonmelanoma ...