When Black and White Turns Gray: Navigating the Ethical Challenges of Implementing Shared Infant Feeding Decisions for Persons Living with Human Immunodeficiency Virus in the United States [0.03%]
当黑白变灰：在美国为感染人类免疫缺陷病毒的人实施共享婴儿喂养决策的伦理挑战导航
Kira J Nightingale,Elizabeth D Lowenthal,Marielle S Gross
Kira J Nightingale
In 2023, US guidelines for feeding perinatally human immunodeficiency virus (HIV)-exposed infants were revised to encourage collaborative decision-making in lieu of categorical proscription of breastfeeding. This change advances autonomy an...
Human Immunodeficiency Virus and Breastfeeding: Clinical Considerations and Mechanisms of Transmission in the Modern Era of Combined Antiretroviral Therapy [0.03%]
联合抗逆转录病毒治疗时代的人类免疫缺陷病毒与母乳喂养：临床注意事项及传播机制
Jenna S Powers,Medrine Kihanga,Lisa Marie Cranmer
Jenna S Powers
Combined antiretroviral therapy has significantly reduced perinatal human immunodeficiency virus (HIV) transmission risk through breastfeeding, prompting shifts in clinical guidance to support breastfeeding for women with HIV who have susta...
Krithika P Karthigeyan,Christian Binuya,Kenneth Vuong et al.
Krithika P Karthigeyan et al.
Despite increased uptake of antiretroviral therapy (ART) among pregnant people living with human immunodeficiency virus (HIV), vertical transmission remains the most important route of pediatric HIV acquisition. The numbers of HIV acquisiti...
Lynda Stranix-Chibanda,Kristina Brooks,Ahizechukwu C Eke
Lynda Stranix-Chibanda
Managing human immunodeficiency virus (HIV) during pregnancy requires attention to psychosocial aspects of maternal health in addition to providing medical and obstetric care. Ideal care plans promote sustained HIV suppression and optimize ...
Lina F Chalak
Lina F Chalak
Lucky Jain
Lucky Jain
Pipeline to Neonatal Clinical Transformation: The Importance of Preclinical Data [0.03%]
从临床前数据到新生儿临床转化的途径：临床前数据的重要性
Sandra E Juul,Thomas R Wood
Sandra E Juul
Historically, neonatal neuroscience boasted a robust and successful preclinical pipeline for therapeutic interventions, in particular for the treatment of hypoxic-ischemic encephalopathy (HIE). However, since the successful translation of t...
Ethical and Legal Perspectives on the Treatment of Hypoxic Ischemic Encephalopathy in the Newborn [0.03%]
新生儿缺氧缺血性脑病的治疗伦理和法律观点
Alice C Baker,Mark R Mercurio,Steven M Donn et al.
Alice C Baker et al.
Hypoxic ischemic encephalopathy (HIE) in neonates can cause severe, life-long functional impairments or death. Treatment of these neonates can involve ethically challenging questions about if, when, and how it may be appropriate to limit li...
Communicating with Parents About Therapeutic Hypothermia and Hypoxic Ischemic Encephalopathy: Integrating a Palliative Care Approach into Practice [0.03%]
有关治疗性降温和缺氧-缺血性脑病的亲子沟通：将姑息治疗融入实践体系中
Alexa K Craig,Sara Munoz-Blanco,Betsy Pilon et al.
Alexa K Craig et al.
Parents of newborns with hypoxic ischemic encephalopathy (HIE) can face communication challenges in the neonatal intensive care unit. Both specialty palliative care and primary palliative care trained clinicians can assist parents as they n...
Simone L Huntingford,Stephanie M Boyd,Sarah J McIntyre et al.
Simone L Huntingford et al.
Hypoxic ischemic encephalopathy (HIE) is the most common cause of neonatal encephalopathy and results in significant morbidity and mortality. Long-term outcomes of the condition encompass impairments across all developmental domains. While ...