Myths of Randomized Controlled Trial Analysis in Pediatric Psychopharmacology [0.03%]
儿童精神药物学中随机对照试验分析的误区
Jeffrey A Mills,Jeffrey R Strawn
Jeffrey A Mills
Viloxazine Extended-Release Administered With Psychostimulants in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder: A Phase 4, Open-Label Trial [0.03%]
在注意缺陷/多动障碍儿童和青少年中进行的viloxazine缓释剂与拟交感神经药物联合用药的临床四期开放标签试验
Ann Childress,Kobby Asubonteng,Georgette Cox et al.
Ann Childress et al.
Introduction: Viloxazine extended-release (VLX-ER) is effective as monotherapy for attention-deficit/hyperactivity disorder (ADHD), and is often tried as an add-on treatment when psychostimulant therapy fails to provide an adequate treatmen...
From the Editor-in-Chief's Desk: Psychedelic Therapeutics-Something Old and Something New [0.03%]
总编辑手记： psychedelic治疗药物的新老动态
Paul E Croarkin
Paul E Croarkin
Safety Outcomes from a Long-Term, Prospective Study of Sertraline Use in Children and Adolescents: The Sertraline Pediatric Registry for the Evaluation of Safety [0.03%]
长期前瞻性研究儿童和青少年使用舍曲林的安全结果：舍曲林儿科登记评估安全性的应用
Sara Ramaker,Francesca Kolitsopoulos,Lisa Ludwig et al.
Sara Ramaker et al.
Objectives: To describe the Sertraline Pediatric Registry for the Evaluation of Safety (SPRITES) safety results, including adverse events (AEs) (serious and nonserious, including suicide-related events) following long-term treatment with se...
Safety and Efficacy of Brexpiprazole in the Treatment of Irritability Associated with Autism Spectrum Disorder: An 8-Week, Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial and 26-Week Open-Label Extension in Children and Adolescents [0.03%]
布雷哌唑治疗与自闭症谱系障碍相关易怒的安全性和有效性：一项为期8周的3期随机双盲安慰剂对照试验及儿童和青少年的26周开放标签扩展研究
Caroline Ward,Ann Childress,Krista Martinko et al.
Caroline Ward et al.
Introduction: The effective management of irritability is a key need in young people with autism spectrum disorder (ASD). We evaluated the efficacy and safety of brexpiprazole in children and adolescents with irritability associated with AS...
Predictors of Placebo Response in the Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors [0.03%]
自闭症研究中预测安慰剂对改善双向社交行为的oxytocin影响因素
Alyssa Verdes,Suvekcha Bhattachan,Alexander Kolevzon et al.
Alyssa Verdes et al.
Background: Although randomized clinical trials (RCTs) have investigated several treatments for social communication difficulties and repetitive behavior in autism, none has yet shown consistent superiority over placebo. Placebo response in...
The Safety and Clinical Effects of Amisulpride in Children and Adolescents with Psychiatric Disorders: A Case Series [0.03%]
阿米舒必利在患有精神疾病的儿童和青少年中的安全性和临床效果：病例系列研究
Osman Özdemir
Osman Özdemir
Objectives: The objective of this study was to explore the safety and clinical effects of amisulpride in children and adolescents with psychiatric disorders. Methods: This case series included six patients, aged 11 to 19 years, diagnosed wi...
False Positives for Criterion A Trauma Events and Posttraumatic Stress Disorder Symptoms with Questionnaires Are Common in Children and Adolescents and Could Not be Eliminated with Enhanced Instructions [0.03%]
儿童和青少年创伤事件及 PTSD 症状问卷的假阳性率较高且增强指令无法消除此类现象
Michael S Scheeringa
Michael S Scheeringa
Objective: Self-report questionnaires are common for measuring posttraumatic stress disorder (PTSD). The experience of life threat-Criterion A-serves a gatekeeper function for diagnosing PTSD, and evidence suggests false positives are commo...
The Aberrant Behavior Checklist for Fragile X Syndrome: A Qualitative Clinician Evaluation of Content Validity [0.03%]
脆性X综合征行为清单的临床内容效度评价
Lindsay M Oberman,Elizabeth Berry-Kravis,Dejan B Budimirovic et al.
Lindsay M Oberman et al.
Objective: The current intense period of drug development for fragile X syndrome (FXS) and other neurodevelopmental disorders (NDDs) indications has highlighted the importance of behavioral outcome measures with strong psychometric properti...
Rett Syndrome Behaviour Questionnaire: Variability of Scores and Related Factors [0.03%]
雷特综合征行为问卷：评分变异及影响因素分析
Walter E Kaufmann,Lindsay M Oberman,Jenny Downs et al.
Walter E Kaufmann et al.
Objective: Rett syndrome (RTT) is a severe neurodevelopmental disorder affecting predominantly females and associated with variants in the MECP2 gene. Recent success in clinical trials have resulted in an expanded use of the Rett Syndrome B...