Medication Prescribing Patterns at a Youth Mental Health Service: A Single Center Retrospective Cross-sectional Study [0.03%]
青年心理健康服务机构的药物处方模式：一项单中心回顾性横断面研究
Angela Dinh,Sarira El-Den,Jack C Collins et al.
Angela Dinh et al.
Objective: Rates of mental illness among young people remain elevated, and the utilization of youth mental health services is expected to increase. Yet, there is limited knowledge on real-world medication usage and prescribing at these serv...
Psychiatric Polygenic Risk Scores and Week-by-Week Symptomatic Status in Youth with Bipolar Disorder: An Exploratory Study [0.03%]
精神疾病多基因风险评分与双相情感障碍青少年的每周症状状态：一项探索性研究
Xinyue Jiang,Clement C Zai,John Merranko et al.
Xinyue Jiang et al.
Introduction: Prior studies have demonstrated that, in both adults and youth, bipolar disorder (BD) is a polygenic illness. However, no studies have examined polygenic risk scores (PRSs) in relation to the longitudinal course of mood sympto...
Treat to Sedation: Managing Intravenous Placement for Electroconvulsive Therapy in Autism with Intellectual Disability and Hyperactive Catatonia [0.03%]
镇静治疗：如何在自闭症、智力障碍和过度活跃的木僵状态中进行电休克疗法的静脉置管管理
Aparna Srinivasan,James Luccarelli,Rafael Tamargo et al.
Aparna Srinivasan et al.
Purpose: Catatonia is a severe psychomotor and mood-related disorder, which can significantly impact the quality of life for autistic individuals. Often, electroconvulsive therapy (ECT) is required for treatment of catatonia in autism. Howe...
Myths of Randomized Controlled Trial Analysis in Pediatric Psychopharmacology [0.03%]
儿童精神药物学中随机对照试验分析的误区
Jeffrey A Mills,Jeffrey R Strawn
Jeffrey A Mills
Viloxazine Extended-Release Administered With Psychostimulants in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder: A Phase 4, Open-Label Trial [0.03%]
在注意缺陷/多动障碍儿童和青少年中进行的viloxazine缓释剂与拟交感神经药物联合用药的临床四期开放标签试验
Ann Childress,Kobby Asubonteng,Georgette Cox et al.
Ann Childress et al.
Introduction: Viloxazine extended-release (VLX-ER) is effective as monotherapy for attention-deficit/hyperactivity disorder (ADHD), and is often tried as an add-on treatment when psychostimulant therapy fails to provide an adequate treatmen...
From the Editor-in-Chief's Desk: Psychedelic Therapeutics-Something Old and Something New [0.03%]
总编辑手记： psychedelic治疗药物的新老动态
Paul E Croarkin
Paul E Croarkin
Safety Outcomes from a Long-Term, Prospective Study of Sertraline Use in Children and Adolescents: The Sertraline Pediatric Registry for the Evaluation of Safety [0.03%]
长期前瞻性研究儿童和青少年使用舍曲林的安全结果：舍曲林儿科登记评估安全性的应用
Sara Ramaker,Francesca Kolitsopoulos,Lisa Ludwig et al.
Sara Ramaker et al.
Objectives: To describe the Sertraline Pediatric Registry for the Evaluation of Safety (SPRITES) safety results, including adverse events (AEs) (serious and nonserious, including suicide-related events) following long-term treatment with se...
Safety and Efficacy of Brexpiprazole in the Treatment of Irritability Associated with Autism Spectrum Disorder: An 8-Week, Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial and 26-Week Open-Label Extension in Children and Adolescents [0.03%]
布雷哌唑治疗与自闭症谱系障碍相关易怒的安全性和有效性：一项为期8周的3期随机双盲安慰剂对照试验及儿童和青少年的26周开放标签扩展研究
Caroline Ward,Ann Childress,Krista Martinko et al.
Caroline Ward et al.
Introduction: The effective management of irritability is a key need in young people with autism spectrum disorder (ASD). We evaluated the efficacy and safety of brexpiprazole in children and adolescents with irritability associated with AS...
Predictors of Placebo Response in the Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors [0.03%]
自闭症研究中预测安慰剂对改善双向社交行为的oxytocin影响因素
Alyssa Verdes,Suvekcha Bhattachan,Alexander Kolevzon et al.
Alyssa Verdes et al.
Background: Although randomized clinical trials (RCTs) have investigated several treatments for social communication difficulties and repetitive behavior in autism, none has yet shown consistent superiority over placebo. Placebo response in...
The Safety and Clinical Effects of Amisulpride in Children and Adolescents with Psychiatric Disorders: A Case Series [0.03%]
阿米舒必利在患有精神疾病的儿童和青少年中的安全性和临床效果：病例系列研究
Osman Özdemir
Osman Özdemir
Objectives: The objective of this study was to explore the safety and clinical effects of amisulpride in children and adolescents with psychiatric disorders. Methods: This case series included six patients, aged 11 to 19 years, diagnosed wi...