Effective Integration of Single-Cell Multi-Omics Data Using Improved Network-Based Integrative Clustering with Multigraph Regularization [0.03%]
基于改进的多重图正则化网络整合聚类的有效单细胞多组学数据集成方法
Shunqin Zhang,Wei Kong,Shuaiqun Wang et al.
Shunqin Zhang et al.
The purpose of integrating different omics data is to study cellular heterogeneity at the level of transcriptional regulation from different gene levels, which can effectively identify cell types and reveal the pathogenesis of Alzheimer's d...
XVir: A Transformer-Based Architecture for Identifying Viral Reads from Cancer Samples [0.03%]
XVir：一种基于Transformer的从癌症样本中识别病毒读段的架构
Shorya Consul,John Robertson,Haris Vikalo
Shorya Consul
It is estimated that approximately 15% of cancers worldwide can be linked to viral infections. The viruses that can cause or increase the risk of cancer include human papillomavirus, hepatitis B and C viruses, Epstein-Barr virus, and human ...
Comparative Performance Evaluation of Large Language Models for Extracting Molecular Interactions and Pathway Knowledge [0.03%]
大型语言模型提取分子互作和信号通路知识的性能评估研究
Gilchan Park,Byung-Jun Yoon,Xihaier Luo et al.
Gilchan Park et al.
Understanding the interactions and regulatory relationships among biomolecules is essential for deciphering complex biological systems and elucidating the mechanisms behind diverse biological functions. Traditionally, the collection of such...
Special Section: 12th International Computational Advances in Bio and Medical Sciences (ICCABS 2023) [0.03%]
第十二届国际生物和医学科学计算进展研讨会（ICCABS 2023）特邀专题讲座
Mukul S Bansal,Wei Chen,Yury Khudyakov et al.
Mukul S Bansal et al.
Paulo Henrique Ribeiro,Jorge Francisco Cutigi,Rodrigo Henrique Ramos et al.
Paulo Henrique Ribeiro et al.
Cancer is a complex disease caused by mutations in the genome of cells. Genetic mutations can be divided into driver mutations, which are significant for the initiation and progression of cancer, and passenger mutations, which have a neutra...
Natalie Wang,Casey Overby Taylor
Natalie Wang
Polypharmacy, the concurrent use of multiple drugs to treat a single condition, is common in patients managing multiple or complex conditions. However, as more drugs are added to the treatment plan, the risk of adverse drug events (ADEs) ri...
Martí Cortada Garcia,Adrià Diéguez Moscardó,Marta Casanellas
Martí Cortada Garcia
We introduce GenPhylo, a Python module that simulates nucleotide sequence data along a phylogeny avoiding the restriction of continuous-time Markov processes. GenPhylo uses directly a general Markov model and therefore naturally incorporate...
Effloc: An Efficient Locating Algorithm for Mass-Occurrence Biological Patterns with FM-Index [0.03%]
利用FM索引的大规模生物模式高效定位算法EFFLOC研究
Li-Lu Guo
Li-Lu Guo
Pattern locating is a crucial step in various biological sequence analysis tasks. As a compressed full-text indexing technology, full-text minute-space index has been introduced for biological pattern locating over ultra-long genomes, with ...
VTrans: A VAE-Based Pre-Trained Transformer Method for Microbiome Data Analysis [0.03%]
基于变分自编码器的预训练变换器方法在微生物组数据分析中的应用(VTrans)
Xinyuan Shi,Fangfang Zhu,Wenwen Min
Xinyuan Shi
Predicting the survival outcomes and assessing the risk of patients play a pivotal role in comprehending the microbial composition across various stages of cancer. With the ongoing advancements in deep learning, it has been substantiated th...