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Rebuttal to Flaws in the Paper 'Nearly Instantaneous Time-Varying Reproduction Number for Contagious Diseases-a Direct Approach Based on Nonlinear Regression' [0.03%]
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Jūratė Šaltytė Benth
Chenyang Yuan,Shunzhou Jiang,Songyun Li et al.
Chenyang Yuan et al.
With the rapid development of single-cell RNA sequencing (scRNA-seq) technology, researchers can now investigate gene expression at the individual cell level. Identifying cell types via unsupervised clustering is a fundamental challenge in ...
The Asymptotic Distribution of the k-Robinson-Foulds Dissimilarity Measure on Labeled Trees [0.03%]
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Michael Fuchs,Mike Steel
Michael Fuchs
Motivated by applications in medical bioinformatics, Khayatian et al. (2024) introduced a family of metrics on Cayley trees [the k-Robinson-Foulds (RF) distance, for k = 0, . . . ,n-2] and explored their distribution on pairs of random Cayl...
Pablo M Redondo,Reza Mousapour,Wayne B Hayes
Pablo M Redondo
Community detection is a long-standing problem with applications from social networks to biology. Given its popularity and that it is NP-complete, heuristics abound, though no gold standard exists-there is even disagreement on the technical...
MFF-HPO: Protein-Phenotype Associations Prediction Based on Sequence Using Multi-Feature Fusion [0.03%]
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Xuehua Bi,Zhuocheng Ji,Linlin Zhang et al.
Xuehua Bi et al.
Protein abnormalities disrupt various cellular and contribute to disease development. Identifying disease-associated proteins is crucial for precision medicine, but traditional methods are time-consuming and costly, necessitating computatio...
A Innovative Strategy for Identifying Subtypes Through the Analysis of Multi-Omics Data with Adversarial Autoencoders [0.03%]
基于对抗自编码器的多组学数据亚型识别方法
Xia Chen,Hao Nie,Quanwei Chen et al.
Xia Chen et al.
Cancer is a disease that is both complex and diverse, and effective diagnosis and treatment require an accurate depiction of tumor subtypes. Traditional methods of cancer identification, which rely on clinical and histopathological criteria...
Leyi Hu,Xuan Liu,Xiangyu Qu et al.
Leyi Hu et al.
Biogeography-based optimization (BBO) is an intelligent evolutionary algorithm based on biological populations, increasing the optimization search ability by adaptive migration operation. However, the original BBO is only feasible for conti...
Counterfactual Debiased Co-Embedding Model for Enhanced Drug-Drug Interaction Prediction [0.03%]
一种改进药物相互作用预测的反事实去偏置共嵌入模型
Xue Pan,Chunping Ouyang,Linlin Zhang et al.
Xue Pan et al.
Predicting drug-drug interactions (DDIs) is critical to drug discovery and development because adverse interactions pose serious health risks. Most of the existing studies utilize the properties of drugs or network topology information of D...
RNAS-sgRNA: Recurrent Neural Architecture Search for Detection of On-Target Effects in Single Guide RNA [0.03%]
基于循环神经网络的sgRNA脱靶效应预测模型
Shehla Rafiq,Assif Assad
Shehla Rafiq
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 is a leading genomic editing tool, but its effectiveness is limited by considerable heterogeneity in target efficiency among different single guide RNAs (sgRNA). This s...