Zebrafish as Versatile Model for Assessing Animal Venoms and Toxins: Current Applications and Future Prospects [0.03%]
斑马鱼在评估动物毒液和毒素中的多功能模型作用：当前应用及未来前景
Fajar Sofyantoro,Nur Indah Septriani,Donan Satria Yudha et al.
Fajar Sofyantoro et al.
Animal venoms and toxins hold promise as sources of novel drug candidates, therapeutic agents, and biomolecules. To fully harness their potential, it is crucial to develop reliable testing methods that provide a comprehensive understanding ...
Optimization of Zebrafish Larvae 6-OHDA Exposure for Neurotoxin Induced Dopaminergic Marker Reduction [0.03%]
斑马鱼幼鱼多巴胺能神经元损伤的6-OHDA优化诱导方案
Adrian Romero,Armando Sanchez,Jocelyn D Jones et al.
Adrian Romero et al.
Parkinson's disease (PD) is a neurodegenerative disorder that is clinically assessed by motor symptoms associated with the loss of midbrain dopaminergic neurons affecting the quality of life for over 8.5 million people worldwide. The neurot...
Heritable CRISPR Mutagenesis of Essential Maternal Effect Genes as a Simple Tool for Sustained Population Suppression of Invasive Species in a Zebrafish Model [0.03%]
利用斑马鱼模型在重要母体作用基因中可遗传的CRISPR突变作为抑制入侵物种种群的持久性工具的一种简单方法
Christopher J Krueger,Zhifei Dai,Cheng Zhu et al.
Christopher J Krueger et al.
Invasive species control is important for ecological and agricultural management. Genetic methods can provide species specificity for population control. We developed heritable maternal effect embryo lethality (HMEL), a novel strategy allow...
Eric Paulissen,Benjamin L Martin
Eric Paulissen
An effective method for tissue-specific ablation in zebrafish is the nitroreductase (NTR)/metronidazole (MTZ) system. Expressing bacterial NTR in the presence of nitroimidazole compounds causes apoptotic cell death, which can be useful for ...
Initial Steps of XY Sex Chromosome Differentiation in the Armored Catfish Hypostomus albopunctatus (Siluriformes: Loricariidae) Revealed by Heterochromatin Accumulation [0.03%]
甲壳鲶(Hypostomus albopunctatus)XY性染色体分化的初期步骤：异染色质的积累(Siluriformes: Loricariidae)
Ligia Carla Balini,Carlos Alexandre Fernandes,Ana Luiza de Brito Portela-Castro et al.
Ligia Carla Balini et al.
In fish species, heterochromatinization is one process that could trigger sex chromosome differentiation. The present article describes a nascent XX/XY sex chromosome system evidenced by heterochromatin accumulation and microsatellite (GATA...
Modified Procedure for Simple and Rapid Collection of Zebrafish Fluid Samples for Biochemical Analyses [0.03%]
斑马鱼体液样本的简化快速收集方法的改进及生化分析
Ana Paula Apolinário da Silva,João Xavier da Silva Neto,José Ytalo Gomes da Silva et al.
Ana Paula Apolinário da Silva et al.
This study addresses the challenge of collecting blood samples from zebrafish for biochemical analysis. Traditional methods are cumbersome due to low blood flow and rapid coagulation. Based on a previously published technique, we simplified...
Katherine M Silvius,Genevieve C Kendall
Katherine M Silvius
The tp53M214K zebrafish mutant is a versatile platform with which to model a diverse spectrum of human diseases. However, currently available genotyping methods for this mutant require lengthy hands-on processes such as restriction digests ...
Correction to: In Vitro Storage of Functional Sperm at Room Temperature in Zebrafish and Medaka Zebrafish 2023;20(6):229-235; doi: 10.1089/zeb.2023.0054 [0.03%]
校正：斑马鱼和中麻鱼在室温下体外保存有功能的精子斑马鱼 2023;20(6):229-235; doi: 10.1089/zeb.2023.0054
Published Erratum
Zebrafish. 2024 Feb;21(1):69. DOI:10.1089/zeb.2023.0054.correx 2024
Chemical and Visual Cues as Modulators of the Stress Response to Social Isolation in the Marine Medaka, Oryzias melastigma [0.03%]
化学和视觉线索作为调节海洋斑胎带鱼(Oryzias melastigma)社会隔离应激反应的调控因子
Alexandre Lebel,Libin Zhang,David Gonçalves
Alexandre Lebel
The marine medaka is emerging as a potential behavioral model organism for ocean studies, namely on marine ecotoxicology. However, not much is known on the behavior of the species and behavioral assays lack standardization. This study asses...
Current Status of the Zebrafish Euthanasia and Humane Endpoint in the Republic of Korea and Guideline Suggestion from Nationwide Expert Elicitation: A Model for Other Countries [0.03%]
韩国斑马鱼安乐死和人道终点的现状以及全国专家咨询的指南建议：其他国家可以借鉴的模型
Sang Wha Kim,Won Joon Jung,Seung Hee Han et al.
Sang Wha Kim et al.
Since its introduction as a model organism in the 1980s, the use of zebrafish (Danio rerio) in research has expanded worldwide. Despite its now widespread use in research, guidelines to safeguard the ethical treatment of zebrafish, particul...