Romelie Rieu,Dawn Carnell,Melvin L K Chua et al.
Romelie Rieu et al.
Particle therapy's distinct depth-dose profile may reduce normal-tissue dose while maintaining intensity-modulated radiotherapy-comparable target coverage, thereby potentially lowering treatment-related toxicity and/or enabling safe dose es...
Sujana S Chandrasekhar
Sujana S Chandrasekhar
Somiah Siddiq,Satya V R Garikipati,Tania Kalsi et al.
Somiah Siddiq et al.
The management of head and neck squamous cell cancer in older adults requires an individualized approach that integrates oncologic efficacy with geriatric considerations. Chronological age alone should not preclude curative-intent therapy; ...
Harnessing Artificial Intelligence in Head and Neck Oncology Practice: Data, Diagnosis, and Therapy [0.03%]
头颈肿瘤学中的数据、诊断和治疗的人工智能应用
Karthik N Rao,Claudia F E Kirsch,Hanya Mahmood et al.
Karthik N Rao et al.
Artificial intelligence (AI) has emerged as a transformative tool across the various domains of head and neck oncology. From early screening and risk stratification to diagnosis, staging, personalized treatment, rehabilitation, and research...
Evolving Neoadjuvant, Adjuvant, and Concurrent Systemic Therapy Strategies in Head and Neck Squamous Carcinoma [0.03%]
头颈部鳞癌新辅助、辅助和同期系统治疗策略的演变
Nandini Menon
Nandini Menon
The role of cytotoxic chemotherapy in the neoadjuvant setting has not been well established by older studies, except in the case of larynx preservation. Novel neoadjuvant strategies are being explored, such as the incorporation of immune ch...
Evan M Graboyes,Nosayaba Osazuwa-Peters
Evan M Graboyes
Social determinants of health (SDOH) and health-related social risks can be measured in the clinical and research realms through patient self-report, composite neighborhood level measures of disadvantage, and Z-codes. Among patients with he...
Surgically Based Deintensification for Oropharyngeal Cancer: Current Concepts and Future Directions [0.03%]
基于手术的喉咽癌去强化治疗：当前概念与未来方向
Michael C Topf,Thomas Kjaergaard,Catherine Po Ling Chan et al.
Michael C Topf et al.
The paradigm for management of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (HPV + OPC) has evolved significantly in recent years. Following the interim futility analysis of NRG HN005, which reaffirmed standar...
Ajith George,Theofano Tikka,David Conway
Ajith George
Diagnosis, positioned between disease prevention and treatment, is essential for head and neck cancer management. Delays in diagnosis contribute to disease upstaging, leading to more complex treatment with poorer survival and functional out...
Stephanie A Joe
Stephanie A Joe
Times of distress and personal setbacks can diminish a person's confidence. Such periods of adversity can disrupt emotional and physical well-being. In these situations, seeking support can feel embarrassing or uncomfortable. Building perso...
Novel Treatment Approaches in Recurrent/Metastatic Squamous Head and Neck Cancer [0.03%]
复发/转移性 squamous head and neck cancer的新治疗策略
Sandra Llop,Pablo Jiménez-Labaig,Ilaria Micheletto et al.
Sandra Llop et al.
The prognosis of recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) remains poor, with most patients presenting with primary or acquired resistance to immune checkpoint inhibitors (ICIs). Upon progression on ICIs, the only s...