Reframing Surgical Decision-Making When Treating Severe Pulmonary Hypertension: Beyond the Binary of Lungs Alone versus Combined Heart-Lung Transplantation [0.03%]
严重肺动脉高压外科治疗决策的再思考:单一肺移植和心肺联合移植之外的选择
Norihisa Shigemura,Chadi A Hage
Norihisa Shigemura
Emilia Maria Swietlik
Emilia Maria Swietlik
Comparative Outcomes of Bilateral Lung and Heart-Lung Transplantation in Primary Pulmonary Arterial Hypertension: A UNOS Database Study [0.03%]
原发性肺动脉高压患者双侧肺移植和心肺联合移植的对比研究:来自美国器官共享系统数据库的研究
Baharan Zarrabian,Kelly M Pennington,Hector R Cajigas et al.
Baharan Zarrabian et al.
Background: In end-stage primary pulmonary arterial hypertension (PAH), chronically elevated pulmonary vascular resistance leads to right ventricular (RV) hypertrophy, dilation, and failure, complicating transplant decisi...
Lung Cancer After Lung Transplantation: Early Detection and Curative Surgery Drive Long-Term Survival [0.03%]
肺移植后的肺癌:早期检测和根治性手术驱动长期生存率
Sophie Saing,Kinan El Husseini,Clément Picard et al.
Sophie Saing et al.
Background: Lung cancer (LC) after lung transplantation (LTx) is a rare but severe complication whose treatment and outcomes remain unclear. Methods: ...
Considerations for Endpoints in Lung Transplant Clinical Trials: An ISHLT Consensus Statement [0.03%]
肺移植临床试验终点的考虑事项:ISHLT共识声明
John R Greenland,Michael Perch,Kieran Halloran et al.
John R Greenland et al.
Clinical trials in lung transplantation have been hindered by a lack of clarity on the formulation and significance of endpoints for evaluating therapeutic efficacy. To address this challenge, a multidisciplinary working group from the Inte...
Author Insights on the ISHLT Perioperative Utilization of ECLS In Lung Transplantation Consensus [0.03%]
国际心肺移植协会围手术期体外膜氧合在肺移植中应用共识专家解读
Archer Kilbourne Martin,Olaf Mercier,Brandi Bottiger et al.
Archer Kilbourne Martin et al.
The International Society for Heart and Lung Transplantation Consensus for Perioperative Utilization of Extracorporeal Life Support in Lung Transplantation consists of 111 Delphi-derived statements across 3 separate manuscripts. These state...
Distinct Plasma Proteome in Severe Pulmonary Hypertension Associated with Chronic Lung Disease [0.03%]
与慢性肺疾病相关的严重肺动脉高压的血浆蛋白组学特征不同
Adelaida Bosacoma,Agustín R Garcia,Juan-José Lozano et al.
Adelaida Bosacoma et al.
Background: The mechanisms underlying the development and severity of pulmonary hypertension (PH) in chronic lung diseases (CLD) remain incompletely understood. To identify relevant pathobiological pathways, we analyzed t...
Enhanced Detection of Antibody-Mediated Rejection Using the Tissue-Based Molecular Microscope Diagnostic System (MMDx) [0.03%]
基于组织的分子显微镜诊断系统(MMDx)在抗体介导的排斥反应检测中的应用优势
Andrea Fernandez Valledor,Cathrine M Moeller,Daniel Oren et al.
Andrea Fernandez Valledor et al.
Background: Advances in rejection diagnostics are reshaping post-transplant surveillance. The Molecular Microscope Diagnostic System (MMDx), which analyzes biopsy-derived transcriptomic profiles, may address limitations o...
Ioannis Dimarakis,Jay D Pal
Ioannis Dimarakis
Less RV Contractility but More Afterload after LVAD: How Two Wrongs Ache the Right [0.03%]
右心收缩功能减低但左心室辅助装置术后负荷增加:两“错”得其“正”的原理如何?
Paul J Scheel rd,Steven Hsu
Paul J Scheel rd