Chimeric SCID-hu Model as a Human Hematopoietic Stem Cell Host That Recapitulates the Effects of HIV-1 on Bone Marrow Progenitors in Infected Patients [0.03%]
嵌合SCID-hu模型可作为人类造血干细胞宿主重现HIV-1感染患者骨髓祖细胞的变化
I Birgitta Sundell,Prasad S Koka
I Birgitta Sundell
The chimeric small animal model system wherein the severe combined immunodeficient mouse is transplanted with human fetal thymus and liver tissues (SCID-hu Thy/Liv) has been used in different areas of experimental research [1]. A living mod...
Natural Killer Cell Receptor NKG2A/HLA-E Interaction Dependent Differential Thymopoiesis of Hematopoietic Progenitor Cells Influences the Outcome of HIV Infection [0.03%]
造血干细胞中天然杀伤细胞受体NKG2A/HLA-E相互作用依赖的胸腺生成差异影响艾滋病病毒感染后的预后
Edmond J Yunis,Viviana Romero,Felipe Diaz-Giffero et al.
Edmond J Yunis et al.
HIV infection and its outcome is complex because there is great heterogeneity not only in clinical presentation, incomplete clinical information of markers of immunodeficiency and in measurements of viral loads. Also, there many gene varian...