Insomnia with Short Sleep Duration: Nosological, Diagnostic, and Treatment Implications [0.03%]
短睡眠性失眠的诊断及治疗含义
Alexandros N Vgontzas,Julio Fernandez-Mendoza
Alexandros N Vgontzas
The diagnosis of insomnia is based solely on subjective complaints. This has contributed to the low reliability and validity of the current nosology of insomnia as well as to its lack of firm association with clinically relevant outcomes su...
Jason C Ong,Megan R Crawford
Jason C Ong
Optimizing the Pharmacologic Treatment of Insomnia: Current Status and Future Horizons [0.03%]
失眠症药物治疗的现状与未来展望
Jared Minkel,Andrew D Krystal
Jared Minkel
A number of medications are available for treating patients with insomnia. These medications include agents approved as insomnia therapies by the U.S. Food and Drug Administration (FDA), agents approved by the FDA for another condition that...
Edmond H L Chau,Babak Mokhlesi,Frances Chung
Edmond H L Chau
Christina S McCrae,Joseph M Dzierzewski,Daniel Kay
Christina S McCrae
Christopher J Watson,Helen A Baghdoyan,Ralph Lydic
Christopher J Watson
The development of sedative/hypnotic molecules has been empiric rather than rational. The empiric approach has produced clinically useful drugs but for no drug is the mechanism of action completely understood. All available sedative/hypnoti...
Bradley F Boeve
Bradley F Boeve
Keith C Summa,Fred W Turek
Keith C Summa
Sleep is a fundamental behavior in higher animals that has been firmly established to be under substantial genetic control. However, the identification of individual genes responsible for primary sleep-wake traits has largely eluded researc...
David M Raizen,John E Zimmerman
David M Raizen