Future of Sleep Medicine: Novel Approaches and Measures Derived from Physiologic Systems Dynamics (Part I) [0.03%]
睡眠医学的未来：基于生理系统动力学的新型方法和措施（一）
Plamen Ch Ivanov,Ronny P Bartsch
Plamen Ch Ivanov
We review recent progress in understanding fundamental aspects of physiologic regulation during wake and sleep based on modern data-driven, analytical, and computational approaches with a focus on the complex dynamics of individual physiolo...
Allan Pack
Allan Pack
All areas of medicine are focused on developing a personalized approach to diagnosis and treatment of specific conditions. This is based on the fundamental concept that all subjects with apparently the same disorder are different. There are...
Gonzalo Labarca,Mario Henríquez-Beltrán,Ludovico Messineo
Gonzalo Labarca
Obstructive sleep apnea (OSA) is a common condition linked with multiple comorbidities. Continuous positive airway pressure (CPAP) devices, though the gold standard for OSA treatment, often do not address the entirety of the disorder. Vario...
Daniil Lisik,Ding Zou
Daniil Lisik
Obstructive sleep apnea (OSA) is a heterogeneous condition characterized by diverse endotypic traits and clinical phenotypes. A recent randomized controlled trial evaluating a glucagon-like peptide-1 receptor agonist showed promising result...
Meir H Kryger,Robert Joseph Thomas
Meir H Kryger
The past of sleep medicine is rich with seminal discoveries, from the recognition of clinical syndromes to measurement of sleep itself to classic and novel therapeutics. Advances in neurobiology have mapped a number of sleep circuits, descr...
Melissa P Knauert
Melissa P Knauert
Olurotimi Adekolu,Muneeb Ahsan,Andira I Anwar et al.
Olurotimi Adekolu et al.
Sleep deficiency in patients with obstructive sleep apnea (OSA) includes abnormal quality, timing and duration of sleep, and the presence of other comorbid conditions. These include insomnia, circadian misalignment disorders, and periodic l...
Bernie Y Sunwoo,Robert L Owens
Bernie Y Sunwoo
With sleep occupying up to one-third of every adult's life, addressing sleep is essential to overall health. Sleep disturbance and deficiency are common in patients with chronic lung diseases and associated with worse clinical outcomes and ...
Roo Killick,Lachlan Stranks,Camilla M Hoyos
Roo Killick
Epidemiologic studies have demonstrated that short sleep duration is associated with an increased risk of cardio-metabolic health outcomes including cardiovascular disease mortality, coronary heart disease, type 2 diabetes mellitus, hyperte...
Effects of Sleep Deficiency on Risk, Course, and Treatment of Psychopathology [0.03%]
睡眠不足对心理疾病风险、病程和治疗的影响
Molly E Atwood
Molly E Atwood
This article reviews the literature on the relationship between sleep deficiency and unipolar and bipolar depression, anxiety disorders, and posttraumatic stress disorder. We consider the evidence for sleep as a contributory causal factor i...