Suresh Kotagal
Suresh Kotagal
Lourdes M DelRosso,Maria P Mogavero,Oliviero Bruni et al.
Lourdes M DelRosso et al.
Pediatric Restless Sleep Disorder (RSD) is emerging as a distinct entity in sleep medicine, characterized by restless and disruptive sleep patterns in children and adolescents. RSD presents unique challenges in diagnosis and management due ...
Therapy of Childhood Restless Legs Syndrome and Periodic Limb Movement Disorder [0.03%]
儿童不安腿综合征和周期性肢体不宁的治疗
Maria P Mogavero,Lourdes M DelRosso,Giuseppe Lanza et al.
Maria P Mogavero et al.
This article describes the complex landscape of pediatric Restless Legs Syndrome (RLS) and Periodic Limb Movement Disorder (PLMD); prevalent sleep disorders posing challenges to affected children and healthcare providers. It emphasizes a mu...
Iron Metabolism and the Role of Iron Therapy in Pediatric Restless Leg Syndrome [0.03%]
铁代谢及铁剂治疗在儿童不安腿综合征中的作用
Thomas Dye,Narong Simakajornboon
Thomas Dye
Iron metabolism in the body is strictly regulated and organ specific. Intestinal iron absorption is mediated through complex mechanisms and is mainly regulated by a peptide called hepcidin that controls iron fluxes into plasma. Iron is tran...
Anne Marie Morse
Anne Marie Morse
Many medical disorders coexist with restless leg syndrome (RLS) and frequently have a bidirectional relationship. Specific examination of these relationships can help in more timely identification and intervention of RLS, as well as more co...
Valeria Mammarella,Maria Breda,Dario Esposito et al.
Valeria Mammarella et al.
Recent research reported an association between pediatric Restless Leg Syndrome (RLS) and psychiatric disorders, in particular attention-deficit hyperactivity disorder in which shared symptoms, such as restlessness and difficulty concentrat...
Rosalia Silvestri,Irene Aricò
Rosalia Silvestri
Restless legs syndrome (RLS), also known as Willis-Ekbom Disease (WED), has several mimicking conditions that closely resemble many, if not all, of its characteristics. Some of these mimics are particularly prevalent in pediatric population...
Genetics of Restless Legs Syndrome: Insights from Genome-Wide Association Studies [0.03%]
基因组-wide关联研究对不安腿综合征的遗传学研究见解
Barbara Schormair
Barbara Schormair
Genome-wide association studies (GWAS) of common and low-frequency variants have discovered 164 genetic risk loci for restless legs syndrome (RLS) in adult populations of European ancestry. Sex-specific GWAS meta-analyses revealed largely o...
Sangeetha Yoganathan,Biswaroop Chakrabarty
Sangeetha Yoganathan
Pediatric Restless Legs Syndrome (RLS)/Willis Ekbom Disease is prevalent at around 2% with onset around the end of first decade. There is a strong genetic predisposition and no gender preference till late adolescence, with a female preponde...
Periodic Limb Movements of Sleep and Periodic Limb Movement Disorder in Children [0.03%]
儿童睡眠周期性肢体不宁及周期性肢体运动障碍
Julie M Baughn,Christine A Matarese
Julie M Baughn
This article will review the definitions and diagnoses of periodic limb movements of sleep and periodic limb movement disorder (PLMD) in children. This article will highlight the challenges in the diagnosis and treatment of children with PL...